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View Structure Prediction Details

Protein: TFG1
Organism: Saccharomyces cerevisiae
Length: 735 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFG1.

Description E-value Query
Range
Subject
Range
gi|639700 - gi|639700|gb|AAA61640.1| transcription initiation factor TFIIF large subunit
0.0 [1..735] [1..735]
tfg1 - transcription factor TFIIF complex alpha subunit Tfg1
gi|19075967 - gi|19075967|ref|NP_588467.1| hypothetical protein SPCC1620.09c [Schizosaccharomyces pombe 972h-]
2.0E-95 [297..563] [95..356]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-4 [185..338] [33..195]
T2FA_XENLA - General transcription factor IIF subunit 1 OS=Xenopus laevis GN=gtf2f1 PE=2 SV=1
0.004 [349..416] [97..167]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRNPPGSR NGGGPTNASP FIKRDRMRRN FLRMRMGQNG SNSSSPGVPN GDNSRGSLVK  60
   61 KDDPEYAEER EKMLLQIGVE ADAGRSNVKV KDEDPNEYNE FPLRAIPKED LENMRTHLLK 120
  121 FQSKKKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [128-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPVTDFHLPV RLHRKDTRNL QFQLTRAEIV QRQKEISEYK KKAEQERSTP NSGGMNKSGT  60
   61 VSLNNTVKDG SQTPTVDSVT KDNTANGVNS SIPTVTGSSV PPASPTTVSA VESNGLSNGS 120
  121 TSAANGLDGN ASTANLANGR PLVTKLEDAG PAEDPTKVGM VKYDGKEVTN EPEFEEGTMD 180
  181 PLADVAPDGG GRAKRGNLRR KTRQLKVLDE NAKKLRFEE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 9.80911813987926 bayes_pls_golite062009
transcription initiation factor activity 5.81303336834294 bayes_pls_golite062009
transcription regulator activity 3.74982553633054 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.72386143594717 bayes_pls_golite062009
binding 2.67974220661654 bayes_pls_golite062009
transcription coactivator activity 1.13156484215109 bayes_pls_golite062009
protein binding 1.02443871942815 bayes_pls_golite062009
transcription activator activity 0.71834071764197 bayes_pls_golite062009
transcription factor binding 0.590528155685771 bayes_pls_golite062009
transcription cofactor activity 0.322693099994972 bayes_pls_golite062009
catalytic activity 0.315768210630189 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [347-735]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYPWVMEDFD GYNTWVGSYE AGNSDSYVLL SVEDDGSFTM IPADKVYKFT ARNKYATLTI  60
   61 DEAEKRMDKK SGEVPRWLMK HLDNIGTTTT RYDRTRRKLK AVADQQAMDE DDRDDNSEVE 120
  121 LDYDEEFADD EEAPIIDGNE QENKESEQRI KKEMLQANAM GLRDEEAPSE NEEDELFGEK 180
  181 KIDEDGERIK KALQKTELAA LYSSDENEIN PYLSESDIEN KENESPVKKE EDSDTLSKSK 240
  241 RSSPKKQQKK ATNAHVHKEP TLRVKSIKNC VIILKGDKKI LKSFPEGEWN PQTTKAVDSS 300
  301 NNASNTVPSP IKQEEGLNST VAEREETPAP TITEKDIIEA IGDGKVNIKE FGKFIRRKYP 360
  361 GAENKKLMFA IVKKLCRKVG NDHMELKKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [552-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENEINPYLSE SDIENKENES PVKKEEDSDT LSKSKRSSPK KQQKKATNAH VHKEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [607-735]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLRVKSIKNC VIILKGDKKI LKSFPEGEWN PQTTKAVDSS NNASNTVPSP IKQEEGLNST  60
   61 VAEREETPAP TITEKDIIEA IGDGKVNIKE FGKFIRRKYP GAENKKLMFA IVKKLCRKVG 120
  121 NDHMELKKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle