| Protein: | SPT6 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1451 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPT6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1451] | [1..1451] |
|
|
0.0 | [400..1438] | [30..1115] |
|
|
0.0 | [639..1438] | [1..865] |
|
|
0.0 | [3..1438] | [9..1485] |
|
|
0.0 | [274..1437] | [26..1193] |
|
Region A: Residues: [1-336] |
1 11 21 31 41 51
| | | | | |
1 MEETGDSKLV PRDEEEIVND NDETKAPSEE EEGEDVFDSS EEDEDIDEDE DEARKVQEGF 60
61 IVNDDDENED PGTSISKKRR KHKRREREED DRLSEDDLDL LMENAGVERT KASSSSGKFK 120
121 RLKRVGDEGN AAESESDNVA ASRQDSTSKL EDFFSEDEEE EESGLRNGRN NEYGRDEEDH 180
181 ENRNRTADKG GILDELDDFI EDDEFSDEDD ETRQRRIQEK KLLREQSIKQ PTQITGLSSD 240
241 KIDEMYDIFG DGHDYDWALE IENEELENGN DNNEAEEEEI DEETGAIKST KKKISLQDIY 300
301 DLEDLKKNLM TEGDMKIRKT DIPERYQELR AGITDY
|
| Detection Method: |  |
| Confidence: | 31.0 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [337-658] |
1 11 21 31 41 51
| | | | | |
1 GNMSSEDQEL ERNWIAEKIS VDKNFDANYD LTEFKEAIGN AIKFITKENL EVPFIYAYRR 60
61 NYISSREKDG FLLTEDDLWD IVSLDIEFHS LVNKKDYVQR FYAELHIDDP IVTEYFKNQN 120
121 TASIAELNSL QDIYDYLEFK YANEINEMFI NHTGKTGKKH LKNSSYEKFK ASPLYQAVSD 180
181 IGISAEDVGE NISSQHQIHP PVDHPSSKPV EVIESILNAN SGDLQVFTSN TKLAIDTVQK 240
241 YYSLELSKNT KIREKVRSDF SKYYLADVVL TAKGKKEIQK GSLYEDIKYA INRTPMHFRR 300
301 DPDVFLKMVE AESLNLLSVK LH
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| nucleic acid binding | 3.95080521324016 | bayes_pls_golite062009 |
| DNA binding | 3.71771169141041 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.90653390639682 | bayes_pls_golite062009 |
| binding | 2.85946414867169 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.51555240517937 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 2.42617682290608 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.13063800565247 | bayes_pls_golite062009 |
| transcription regulator activity | 2.10110937001387 | bayes_pls_golite062009 |
| RNA binding | 2.07864328706376 | bayes_pls_golite062009 |
| structural molecule activity | 1.9177190829469 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.81524862921454 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.62996999055328 | bayes_pls_golite062009 |
| transcription repressor activity | 1.30343463892105 | bayes_pls_golite062009 |
| excinuclease ABC activity | 1.24466762466323 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| ribonuclease activity | 1.19236946227657 | bayes_pls_golite062009 |
| transcription factor activity | 1.14242112812892 | bayes_pls_golite062009 |
| endonuclease activity | 0.991569665925888 | bayes_pls_golite062009 |
| damaged DNA binding | 0.95191912850966 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.85691075793641 | bayes_pls_golite062009 |
| endoribonuclease activity, producing 5'-phosphomonoesters | 0.708753843279937 | bayes_pls_golite062009 |
| endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.598360955770972 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.583085644017496 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| protein binding | 0.420735403363425 | bayes_pls_golite062009 |
| translation regulator activity | 0.31332179848255 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.263197317040851 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 0.24906263529692 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.2080607201312 | bayes_pls_golite062009 |
| chromatin binding | 0.19409870825073 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 0.125256208482441 | bayes_pls_golite062009 |
| telomerase inhibitor activity | 0.111973370145519 | bayes_pls_golite062009 |
| exoribonuclease activity | 0.109774918833391 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.09423425042945 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.0189279348688405 | bayes_pls_golite062009 |
| endoribonuclease activity | 0.016619833072142 | bayes_pls_golite062009 |
|
Region A: Residues: [659-870] |
1 11 21 31 41 51
| | | | | |
1 MSSQAQYIEH LFQIALETTN TSDIAIEWNN FRKLAFNQAM DKIFQDISQE VKDNLTKNCQ 60
61 KLVAKTVRHK FMTKLDQAPF IPNVRDPKIP KILSLTCGQG RFGADAIIAV YVNRKGDFIR 120
121 DYKIVDNPFD KTNPEKFEDT LDNIIQSCQP NAIGINGPNP KTQKFYKRLQ EVLHKKQIVD 180
181 SRGHTIPIIY VEDEVAIRYQ NSERAAQEFP NK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 3.01525273025469 | bayes_pls_golite062009 |
| transcription regulator activity | 2.33050919783116 | bayes_pls_golite062009 |
| nucleic acid binding | 2.10577358908602 | bayes_pls_golite062009 |
| protein binding | 1.97939552458783 | bayes_pls_golite062009 |
| DNA binding | 1.9368694231327 | bayes_pls_golite062009 |
| transcription factor activity | 1.23187486844263 | bayes_pls_golite062009 |
| molecular adaptor activity | 0.136743230957381 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 0.0218958138395108 | bayes_pls_golite062009 |
|
Region A: Residues: [871-1001] |
1 11 21 31 41 51
| | | | | |
1 PPLVKYCIAL ARYMHSPLLE YANLTSEEVR SLSIHPHQNL LSSEQLSWAL ETAFVDIVNL 60
61 VSVEVNKATD NNYYASALKY ISGFGKRKAI DFLQSLQRLN EPLLARQQLI THNILHKTIF 120
121 MNSAGFLYIS W
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1002-1114] |
1 11 21 31 41 51
| | | | | |
1 NEKRQKYEDL EHDQLDSTRI HPEDYHLATK VAADALEYDP DTIAEKEEQG TMSEFIELLR 60
61 EDPDRRAKLE SLNLESYAEE LEKNTGLRKL NNLNTIVLEL LDGFEELRND FHP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1115-1222] |
1 11 21 31 41 51
| | | | | |
1 LQGDEIFQSL TGESEKTFFK GSIIPVRVER FWHNDIICTT NSEVECVVNA QRHAGAQLRR 60
61 PANEIYEIGK TYPAKVIYID YANITAEVSL LDHDVKQQYV PISYSKDP
|
| Detection Method: | |
| Confidence: | 14.39794 |
| Match: | 1sro__ |
| Description: | S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1223-1374] |
1 11 21 31 41 51
| | | | | |
1 SIWDLKQELE DAEEERKLMM AEARAKRTHR VINHPYYFPF NGRQAEDYLR SKERGEFVIR 60
61 QSSRGDDHLV ITWKLDKDLF QHIDIQELEK ENPLALGKVL IVDNQKYNDL DQIIVEYLQN 120
121 KVRLLNEMTS SEKFKSGTKK DVVKFIEDYS RV
|
| Detection Method: | |
| Confidence: | 7.21 |
| Match: | 1fu5A |
| Description: | Phosphatidylinositol 3-kinase, p85-alpha subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1375-1451] |
1 11 21 31 41 51
| | | | | |
1 NPNKSVYYFS LNHDNPGWFY LMFKINANSK LYTWNVKLTN TGYFLVNYNY PSVIQLCNGF 60
61 KTLLKSNSSK NRMNNYR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
