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View Structure Prediction Details

Protein: TEL2
Organism: Saccharomyces cerevisiae
Length: 688 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TEL2.

Description E-value Query
Range
Subject
Range
gi|1181669 - gi|1181669|gb|AAB60317.1| Tel2p
0.0 [1..688] [1..688]
TEL2_SCHPO - DNA replication checkpoint protein tel2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=te...
SPAC458.03 - nuclear telomere cap complex subunit
0.0 [302..655] [350..742]
TELO2 - TEL2, telomere maintenance 2, homolog (S. cerevisiae)
2.0E-91 [315..658] [379..738]
gi|42602056, gi|... - gi|42602056|gb|AAS21644.1| unknown; 1200003M09Rik protein [Mus musculus], gi|15029722|gb|AAH11077.1|...
6.0E-87 [316..626] [380..704]
gi|30693041, gi|... - gi|7630034|emb|CAB88328.1| putative protein [Arabidopsis thaliana], gi|30693041|ref|NP_680117.2| EMB...
5.0E-74 [311..625] [446..837]
clk-2 - status:Confirmed UniProt:Q95YE9 protein_id:AAK85444.3
3.0E-55 [400..626] [504..739]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLETLKQGL DSSQIHEALI QLDSYPREPV DLDASMVLIK FVIPVYPSLP ERSKVILRRL  60
   61 ASKSFTFLCQ IVTFSRTISG RDGLQEIRIY QEILEDIISF EPGCLTFYLK ASTTSKADRD 120
  121 SIKALFFGSK LFNVLANRID MAKYLGYLRL QWKFLLES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NETDPPGFLG EWLVSSFLLN PVLAADMLLG ELFLLKESYF FSFQKIISAS SLIDQKRLIA  60
   61 KFLLPYIQVI VTLENLNDVR KILRRFDLDK IISLSVLFEI QSLPLKEVIV RLMSNHSSTK 120
  121 FVSALVSKFA DFTDEEVDTK TCELLVLFAV HNLNHSQREE IAHDERFL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [346-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIAKLLSGGH LKYESDFKIN IPNVKFESNS DDKIIDFQSL KNPSICNTQT DVGKDKITEV  60
   61 SGH

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.14
Match: 1h6kA
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [327-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGVTKHLGSN EREARERAM

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [409-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQSLTLDCSD SDDEDENDER EIVKRIVFLK DLMKEYEKTG ESRKAPLIPL LKQTVKLIRQ  60
   61 KADFQLEVGY YAQGILSSIV CLNNEFDEPL FEQWRINALT SILVVLPEKV NGAINILFNS 120
  121 ELSLQQRMSL LSALGLSARE LRGL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.14
Match: 1h6kA
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [553-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDPTIVKPKF DFPTNRLPWD DQSHHNSRLV EVQESTSMIK KTKTVWKSRK LGKDREKGTQ  60
   61 NRFRKYAGLF FYPLAHGWLN GIDVGTYNQL FKSHYLTTLR IIYSCANPVH DFESMTELMN 120
  121 HIISSAIEEG ISLNKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [559-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPKFDFPTNR LPWDDQSHHN SRLVEVQEST SMIKKTKTVW KSRKLGKDRE KGTQNRFRKY  60
   61 AGLFFYPLAH GWLNGIDVGT YNQLFKSHYL TTLRIIYSCA NPVHDFESMT ELMNHIISSA 120
  121 IEEGISLNKG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle