| Protein: | HFM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1187 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HFM1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1187] | [1..1187] |
|
|
0.0 | [22..1024] | [406..1430] |
|
|
0.0 | [6..1013] | [14..1036] |
|
|
0.0 | [6..1013] | [339..1361] |
|
Region A: Residues: [1-107] |
1 11 21 31 41 51
| | | | | |
1 MKTKFDRLGT GKRSRPSPNN IDFNDQSATF KRNKKNSRQP SFKVGLSYNS LLDDCDDENE 60
61 TEEIFEGRGL QFFDKDDNFS ITADDTQVTS KLFDHDLEQT PDEEAKK
|
| Detection Method: |  |
| Confidence: | 37.0 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [108-884] |
1 11 21 31 41 51
| | | | | |
1 PKKVTIRKSA KKCLSTTILP DSFRGVFKFT EFNKMQSEAF PSIYESNENC IISSPTGSGK 60
61 TVLFELAILR LIKETNSDTN NTKIIYIAPT KSLCYEMYKN WFPSFVNLSV GMLTSDTSFL 120
121 ETEKAKKCNI IITTPEKWDL LTRRWSDYSR LFELVKLVLV DEIHTIKEKR GASLEVILTR 180
181 MNTMCQNIRF VALSATVPNI EDLALWLKTN NELPANILSF DESYRQVQLT KFVYGYSFNC 240
241 KNDFQKDAIY NSKLIEIIEK HADNRPVLIF CPTRASTIST AKFLLNNHIF SKSKKRCNHN 300
301 PSDKILNECM QQGIAFHHAG ISLEDRTAVE KEFLAGSINI LCSTSTLAVG VNLPAYLVII 360
361 KGTKSWNSSE IQEYSDLDVL QMIGRAGRPQ FETHGCAVIM TDSKMKQTYE NLIHGTDVLE 420
421 SSLHLNLIEH LAAETSLETV YSIETAVNWL RNTFFYVRFG KNPAAYQEVN RYVSFHSVED 480
481 SQINQFCQYL LDTLVKVKII DISNGEYKST AYGNAMTRHY ISFESMKQFI NAKKFLSLQG 540
541 ILNLLATSEE FSVMRVRHNE KKLFKEINLS PLLKYPFLTE KKQSQIIDRV SQKVSLLIQY 600
601 ELGGLEFPSY EGASKLHQTL VQDKFLVFRH CFRLLKCMVD TFIEKSDGTS LKNTLFLLRS 660
661 LNGHCWENTP MVLRQLKTIG LVSVRRLIRH GITNLEEMGH LSDTQIEYYL NLKIGNGIKI 720
721 KNDISLLPCL NIRTKLENCK IENEELWLTF KVEISATFKS SIWHGQHLSL DIETEKS
|
| Detection Method: | |
| Confidence: | 6.522879 |
| Match: | 1gl9B_ |
| Description: | Helicase-like "domain" of reverse gyrase; Topoisomerase "domain" of reverse gyrase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.4974940028864 | bayes_pls_golite062009 |
| nucleic acid binding | 1.49633029954726 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.49611313354225 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.2155186842031 | bayes_pls_golite062009 |
| helicase activity | 1.16085745407703 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA binding | 0.967303417236485 | bayes_pls_golite062009 |
| transcription regulator activity | 0.748437190903548 | bayes_pls_golite062009 |
| DNA helicase activity | 0.72881469450553 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| microtubule motor activity | 0.38363601832205 | bayes_pls_golite062009 |
| protein binding | 0.378225828131122 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 0.3625050107782 | bayes_pls_golite062009 |
| DNA clamp loader activity | 0.27925703205288 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.249173645231486 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.22150712609541 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.0781650226500197 | bayes_pls_golite062009 |
| DNA polymerase activity | 4.95561462330096E-4 | bayes_pls_golite062009 |
|
Region A: Residues: [885-971] |
1 11 21 31 41 51
| | | | | |
1 SGELIDFRRL QVNKLQSPRG FRISAKISPK LEKIEFSIHC QEIAGLGKTI VYSTDHLASQ 60
61 FSAKTPNIRK DLNSLEKCLF YESSSDG
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.5075656948209 | bayes_pls_golite062009 |
| protein binding | 1.71025015568774 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.71818218589805 | bayes_pls_golite062009 |
| actin binding | 0.68323011536902 | bayes_pls_golite062009 |
|
Region A: Residues: [972-1187] |
1 11 21 31 41 51
| | | | | |
1 EVGKTSRVSH KDGLEESLSS DDSILDYLNE RKKSSKAVES AAVIHPEAHS SSHFSNGRQV 60
61 RSNGNYECFH SCKDKTQCRH LCCKEGIPVK YIKEKGPSSI KPVSKPDQIR QPLLAKNINT 120
121 TPHLEKRLNS KPKQWQEENT DIATVHTLPS KIYNLSQQMS SMEAGEQVLK SGPENCPEII 180
181 PIDLESSDSY SSNTAASSIS DPNGDLDFLG SDIEFE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
