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View Structure Prediction Details

Protein: MCM6
Organism: Saccharomyces cerevisiae
Length: 1017 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM6.

Description E-value Query
Range
Subject
Range
MCM6 - minichromosome maintenance complex component 6
0.0 [172..1009] [21..821]
MCM6_MOUSE - DNA replication licensing factor MCM6 OS=Mus musculus GN=Mcm6 PE=1 SV=1
0.0 [156..1009] [8..821]
gi|2981313 - gi|2981313|gb|AAC41267.1| zygotic DNA replication factor MCM6b [Xenopus laevis]
0.0 [172..1009] [22..824]
Mcm6-PA - The gene Minichromosome maintenance 6 is referred to in FlyBase by the symbol Dmel\Mcm6 (CG4039, FBg...
0.0 [172..1008] [16..817]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [176..983] [27..793]
mcm6 - MCM complex subunit Mcm6
MCM6_SCHPO - DNA replication licensing factor mcm6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mcm6...
0.0 [70..1015] [32..889]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPFPADTP SSNRPSNSSP PPSSIGAGFG SSSGLDSQIG SRLHFPSSSQ PHVSNSQTGP  60
   61 FVNDSTQFSS QRLQTDGSAT NDMEGNEPAR SFKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RALNHVKKVD DVTGEKVREA FEQFLEDFSV QSTDTGEVEK VYRAQIEFMK IYDLNTIYID  60
   61 YQHLSMRENG ALAMAISEQY YRFLAFLQKG LRRVVRKYAP ELLNTSDSLK RSEGDEGQAD 120
  121 EDEQQDDDMN GSSLPRDSGS SAAPGNGTSA MATRSITTST SPEQTERVFQ ISFFN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [270-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTVHRIRDI RSEKIGSLLS ISGTVTRTSE VRPELYKASF TCDMCRAIVD NVEQSFKYTE  60
   61 PTFCPNPSCE NRAFWTLNVT RSRFLDWQKV RIQENANEIP TGSMPRTLDV ILRGDSVERA 120
  121 KPGDRCKFTG VEIVVPDVTQ LGLPGVKPSS TLDTRGISKT TEGLNSGVTG LRSLGVR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 7.055517
Match: PF00493
Description: MCM2/3/5 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [447-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLTYKISFLA CHVISIGSNI GASSPDANSN NRETELQMAA NLQANNVYQD NERDQEVFLN  60
   61 SLSSDEINEL KEMVKDEHIY D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1dbwA_
Description: Transcriptional regulatory protein FixJ, receiver domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [528-759]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLVRSIAPAV FGHEAVKKGI LLQMLGGVHK STVEGIKLRG DINICVVGDP STSKSQFLKY  60
   61 VVGFAPRSVY TSGKASSAAG LTAAVVRDEE GGDYTIEAGA LMLADNGICC IDEFDKMDIS 120
  121 DQVAIHEAME QQTISIAKAG IHATLNARTS ILAAANPVGG RYNRKLSLRG NLNMTAPIMS 180
  181 RFDLFFVILD DCNEKIDTEL ASHIVDLHMK RDEAIEPPFS AEQLRRYIKY AR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 1g8pA_
Description: ATPase subunit of magnesium chelatase, BchI
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [760-867]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFKPILTKEA RSYLVEKYKE LRKDDAQGFS RSSYRITVRQ LESMIRLSEA IARANCVDEI  60
   61 TPSFIAEAYD LLRQSIIRVD VDDVEMDEEF DNIESQSHAA SGNNDDND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 1g8pA_
Description: ATPase subunit of magnesium chelatase, BchI
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [868-1017]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGTGSGVITS EPPADIEEGQ SEATARPGTS EKKKTTVTYD KYVSMMNMIV RKIAEVDREG  60
   61 AEELTAVDIV DWYLLQKEND LGSLAEYWEE RRLAFKVIKR LVKDRILMEI HGTRHNLRDL 120
  121 ENEENENNKT VYVIHPNCEV LDQLEPQDSS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle