YRC Public Data Repository - Protein Structure Prediction

Protein:	SDS23
Organism:	Saccharomyces cerevisiae
Length:	527 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SDS23.

Description	E-value	Query Range	Subject Range
gi\|6321382\|ref\|N... - One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implic... SDS23 - One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implic...	5.0E-78	[1..527]	[1..527]
gi\|220948160 - gi\|220948160\|gb\|ACL86623.1\| SNF4Agamma-PC [synthetic construct] SNF4Agamma-PK, S... - The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dme...	7.0E-51	[70..434]	[413..753]
PRKAG2 - protein kinase, AMP-activated, gamma 2 non-catalytic subunit	8.0E-50	[5..414]	[153..565]
gi\|19570823 - gi\|19570823\|dbj\|BAB86329.1\| Sk-SDS23 [Lachancea kluyveri]	1.0E-47	[5..391]	[23..379]
IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus GN=guaB PE=3 SV=1 IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus (strain VF5) GN=guaB PE=3 SV=1	3.0E-47	[7..411]	[5..363]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQNTRHTSI VEMLSTPPQL PNSTDLNSLS EQTDKNTEAN KSDTESLHKS ISKSSSSSSL  60
   61 STLDNTEYSN NNGNSLSTLN SQNLLSVHRQ EW

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [235-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYLWENARSF PNLKPLLDSS LEELNIGVLN AARDKPTFKQ SRVISIQGDE HLIMALHKMY  60
   61 VERISSIAVV DPQGNLIGNI SVTDVKHVTR TSQYPLLHNT CRHFVSVILN LRGLETGKDS 120
  121 FPIFHVYPTS SLARTFAKLV ATKSHRLWIV QPNDNQPTAS SEKSSSPSPS TPPVTTLPSL 180
  181 ASSYHSNTQS SRMANSPVLK SSDTSNNKIN VNINLSGPSP SQPQSPSATM PP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.09691
Match:	1zfjA_
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [93-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHTPLSNLVE QNKLIFIRGS ISVEEAFNTL VKHQLTSLPV ENFPGDMNCL TFDYNDLNAY  60
   61 LLLVLNRIKV SNDKITSDCQ NGKSVPVAEI VKLTPKNPFY KLPETENLST VIGILGSGVH 120
  121 RVAITNVEMT QIKGILSQRR LI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.09691
Match:	1zfjA_
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [467-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSPSNCPAS PTPAHFEKEY RTGKLIGVVS LTDILSVLAR KQTHHKEIDP QMARKQRGHI  60
   61 G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits