| Protein: | SIZ1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 904 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIZ1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..904] | [1..904] |
|
|
0.0 | [26..508] | [3..490] |
|
|
0.0 | [26..508] | [3..490] |
|
|
0.0 | [33..508] | [1..481] |
|
Region A: Residues: [1-106] |
1 11 21 31 41 51
| | | | | |
1 MINLEDYWED ETPGPDREPT NELRNEVEET ITLMELLKVS ELKDICRSVS FPVSGRKAVL 60
61 QDLIRNFLQN ALVVGKSDPY RVQAVKFLIE RIRKNEPLPV YKDLWN
|
| Detection Method: |  |
| Confidence: | 10.236572 |
| Match: | PF02037 |
| Description: | SAP domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| SUMO ligase activity | 7.09211721404578 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.19208367271658 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.23914967265256 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 2.74673402515898 | bayes_pls_golite062009 |
| binding | 2.26662406320154 | bayes_pls_golite062009 |
| protein binding | 1.60046728943053 | bayes_pls_golite062009 |
| nucleic acid binding | 1.45346081057303 | bayes_pls_golite062009 |
| DNA binding | 1.3220534257427 | bayes_pls_golite062009 |
| transcription regulator activity | 1.24563554819776 | bayes_pls_golite062009 |
| transcription factor binding | 0.6524624181863 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.55208373081056 | bayes_pls_golite062009 |
| catalytic activity | 0.454272578060498 | bayes_pls_golite062009 |
| ligase activity | 0.36302660895622 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.11065840905983 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.0906176057893404 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.0808240821039099 | bayes_pls_golite062009 |
| transcription activator activity | 0.0459673376823702 | bayes_pls_golite062009 |
|
Region A: Residues: [107-219] |
1 11 21 31 41 51
| | | | | |
1 ALRKGTPLSA ITVRSMEGPP TVQQQSPSVI RQSPTQRRKT STTSSTSRAP PPTNPDASSS 60
61 SSSFAVPTIH FKESPFYKIQ RLIPELVMNV EVTGGRGMCS AKFKLSKADY NLL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.344 | 0.423 | protein sumoylation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.334 | 0.033 | protein sumoylation | d.95.2 | Homing endonucleases |
| View | Download | 0.348 | 0.021 | protein sumoylation | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.477 | 0.012 | protein sumoylation | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.352 | 0.004 | protein sumoylation | d.199.1 | DNA-binding C-terminal domain of the transcription factor MotA |
| View | Download | 0.296 | N/A | N/A | d.74.1 | Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) |
| View | Download | 0.271 | N/A | N/A | d.13.1 | HIT-like |
| View | Download | 0.268 | N/A | N/A | d.68.4 | YhbY-like |
| View | Download | 0.238 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.232 | N/A | N/A | d.58.2 | Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain |
| View | Download | 0.217 | N/A | N/A | c.55.3 | Ribonuclease H-like |
| View | Download | 0.207 | N/A | N/A | a.39.1 | EF-hand |
|
Region A: Residues: [220-289] |
1 11 21 31 41 51
| | | | | |
1 SNPNSKHRLY LFSGMINPLG SRGNEPIQFP FPNELRCNNV QIKDNIRGFK SKPGTAKPAD 60
61 LTPHLKPYTQ
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.350 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.255 | a.64.1 | Saposin |
| View | Download | 0.212 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
|
Region A: Residues: [290-410] |
1 11 21 31 41 51
| | | | | |
1 QNNVELIYAF TTKEYKLFGY IVEMITPEQL LEKVLQHPKI IKQATLLYLK KTLREDEEMG 60
61 LTTTSTIMSL QCPISYTRMK YPSKSINCKH LQCFDALWFL HSQLQIPTWQ CPVCQIDIAL 120
121 E
|
| Detection Method: | |
| Confidence: | 33.60206 |
| Match: | PF02891 |
| Description: | MIZ zinc finger |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [411-529] |
1 11 21 31 41 51
| | | | | |
1 NLAISEFVDD ILQNCQKNVE QVELTSDGKW TAILEDDDDS DSDSNDGSRS PEKGTSVSDH 60
61 HCSSSHPSEP IIINLDSDDD EPNGNNPHVT NNHDDSNRHS NDNNNNSIKN NDSHNKNNN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.215 | 0.046 | protein sumoylation | d.38.1 | Thioesterase/thiol ester dehydrase-isomerase |
|
Region A: Residues: [530-904] |
1 11 21 31 41 51
| | | | | |
1 NNNNNNNNNN DNNNSIENND SNSNNKHDHG SRSNTPSHNH TKNLMNDNDD DDDDRLMAEI 60
61 TSNHLKSTNT DILTEKGSSA PSRTLDPKSY NIVASETTTP VTNRVIPEYL GNSSSYIGKQ 120
121 LPNILGKTPL NVTAVDNSSH LISPDVSVSS PTPRNTASNA SSSALSTPPL IRMSSLDPRG 180
181 STVPDKTIRP PINSNSYTAS ISDSFVQPQE SSVFPPREQN MDMSFPSTVN SRFNDPRLNT 240
241 TRFPDSTLRG ATILSNNGLD QRNNSLPTTE AITRNDVGRQ NSTPVLPTLP QNVPIRTNSN 300
301 KSGLPLINNE NSVPNPPNTA TIPLQKSRLI VNPFIPRRPY SNVLPQKRQL SNTSSTSPIM 360
361 GTWKTQDYGK KYNSG
|
| Detection Method: | |
| Confidence: | 8.34 |
| Match: | 1i3qA |
| Description: | RBP1 |
Matching Structure (courtesy of the PDB): |
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