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View Structure Prediction Details

Protein: NCB2
Organism: Saccharomyces cerevisiae
Length: 146 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NCB2.

Description E-value Query
Range		 Subject
Range
gi|147901227, gi... - gi|3170225|gb|AAC82336.1| nuclear Y/CCAAT-box binding factor B subunit NF-YB [Xenopus laevis], gi|14...
 3.0E-43 [2..132] [50..186]
ENSMMUT000000317... - null, null
NFYB - nuclear transcription factor Y, beta
ENSCJAT00000028469 - null
gi|123993257, gi... - gi|60656481|gb|AAX32804.1| nuclear transcription factor Y beta [synthetic construct], gi|208966894|d...
 2.0E-42 [2..132] [51..187]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-42 [2..132] [49..185]
gi|15231796, gi|... - gi|6729485|emb|CAB67641.1| transcription factor NF-Y, CCAAT-binding-like protein [Arabidopsis thalia...
 3.0E-42 [4..145] [28..165]
NFYB_MAIZE - Nuclear transcription factor Y subunit B OS=Zea mays GN=NFY2 PE=2 SV=1
 8.0E-42 [2..146] [28..177]
gi|579588|emb|CA... - unnamed protein product [Homo sapiens]
NFYB_RAT - Nuclear transcription factor Y subunit beta OS=Rattus norvegicus GN=Nfyb PE=1 SV=1
NFYB_MOUSE - Nuclear transcription factor Y subunit beta OS=Mus musculus GN=Nfyb PE=1 SV=1
 1.0E-41 [2..114] [51..164]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 2.0E-41 [2..114] [51..164]
gi|203355 - gi|203355|gb|AAA40888.1| CCAAT binding transcription factor-B subunit
 3.0E-41 [2..114] [13..126]

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Predicted Domain #1
Region A:
Residues: [1-11] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDSDNVSL P

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [35-101] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIIINSGIEF IMILSSMASE MADNEAKKTI APEHVIKALE ELEYNEFIPF LEEILLNFKG  60
   61 SQKVKET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 237.232149
Match: 1jfiB_
Description: Negative cofactor 2, NC2, beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.28941584139552 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.99199798564473 bayes_pls_golite062009
transcription activator activity 2.58408368884371 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
transcription repressor activity 2.3574713307436 bayes_pls_golite062009
protein binding 2.1291876005999 bayes_pls_golite062009
transcription corepressor activity 1.30859203490073 bayes_pls_golite062009
sequence-specific DNA binding 1.18653213156155 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription coactivator activity 0.0885263144317296 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [12-34] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KATVQKMISE ILDQDLMFTK DAR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [102-146] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDSKFKKSGL SEEELLRQQE ELFRQSRSRL HHNSVSDPVK SEDSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 237.232149
Match: 1jfiB_
Description: Negative cofactor 2, NC2, beta chain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle