YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: YDR266C
Organism: Saccharomyces cerevisiae
Length: 639 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR266C.

Description E-value Query
Range
Subject
Range
ZNF347 - zinc finger protein 347
gi|208968133 - gi|208968133|dbj|BAG73905.1| zinc finger protein 347 [synthetic construct]
0.0 [5..476] [317..784]
ZN252_CANLF - Zinc finger protein 252 OS=Canis lupus familiaris GN=ZNF252 PE=2 SV=1
0.0 [7..476] [374..839]
gi|15929737, gi|... - gi|21703954|ref|NP_663458.1| zinc finger protein 160 [Mus musculus], gi|15929737|gb|AAH15291.1| Zinc...
0.0 [3..476] [172..641]

Back

Predicted Domain #1
Region A:
Residues: [1-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESVKENVT PTRNFRRTQG PQNNTKPHND RKNFRRKQKK NNLSAEPNLT TSSADDTDEE  60
   61 NELCVICARK LTYVSLTPCH HKTCHICGFR QRALYNKKSC LICRTENEEV MFTDRIDGDI 120
  121 SDKYNFCEKN EKYGINFTSE EVATETLNLL KFFCPLSKDE QVCDFGSFKK YNEHLKSEHN 180
  181 R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1meyC_
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [182-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MICLICATHK HAFPCELEIF TQNQLRNHQT KGNSEGFKGH PMCAFCSGKR FYSDDELYIH  60
   61 MRNQHEKCHI CDKMNPASPQ YFKDYNQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 2gliA_
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [270-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDHFKHSHYV CTVQTCLDNK FVVFKDELEL QAHILQEHGN ILKGKPKFFQ SELSTFISAP  60
   61 SRVIRERDDY DLPSISSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 2gliA_
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.56793851778364 bayes_pls_golite062009
DNA binding 3.54020314355238 bayes_pls_golite062009
nucleic acid binding 3.5199046417859 bayes_pls_golite062009
binding 2.67810465561307 bayes_pls_golite062009
transcription factor activity 2.55187755119308 bayes_pls_golite062009
transcription activator activity 1.42994934871119 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.39866271783743 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
RNA binding 0.938541269618281 bayes_pls_golite062009
transcription repressor activity 0.929401148394889 bayes_pls_golite062009
sequence-specific DNA binding 0.72547620392762 bayes_pls_golite062009
transcription factor binding 0.70656389852666 bayes_pls_golite062009
chromatin binding 0.67474205629207 bayes_pls_golite062009
mRNA binding 0.529908848614478 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.26938915748667 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription cofactor activity 0.0675941993292299 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [348-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGSSSGSRTD VRSASSPEES RLRLAERAKY YLENSKEDFN KFSSYNEDYS KGRLSAEKLL  60
   61 ESYKLLFTKP NADVYLLIHN LAETFPKNSS KYNNLNAIYE QREQTLARQT SLPSLSSDSS 120
  121 LSMSIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1f2iG_
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [474-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGHWGGTNDG GSAGAALGVR NIKNLPTLKS PSASYDPFAT TVKKNTLRPV QNIKRTTPQS  60
   61 VSYRTSTNTV AFSPTYLESK KGSSSTSLNN SKDKLKSLNL PQLPPPKPKV QIPGLNRPQI 120
  121 ADPKQWGKKS STQDTNVHDN LRELNTTSGG NKKKGKQKQL LFHIGV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle