| Protein: | HEM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 548 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEM1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..548] | [1..548] |
|
|
0.0 | [6..546] | [14..562] |
|
|
0.0 | [27..547] | [54..569] |
|
|
0.0 | [8..528] | [70..602] |
|
|
0.0 | [10..527] | [74..603] |
|
|
0.0 | [2..489] | [69..540] |
|
|
0.0 | [20..534] | [42..560] |
|
|
0.0 | [36..527] | [6..484] |
|
|
0.0 | [10..498] | [65..549] |
|
|
0.0 | [32..490] | [99..541] |
|
Region A: Residues: [1-66] |
1 11 21 31 41 51
| | | | | |
1 MQRSIFARFG NSSAAVSTLN RLSTTAAPHA KNGYATATGA GAAAATATAS STHAAAAAAA 60
61 AANHST
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| L-aspartate:2-oxoglutarate aminotransferase activity | 3.359406422625 | bayes_pls_golite062009 |
| 5-aminolevulinate synthase activity | 3.15163480353521 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| transferase activity | 1.88724762473867 | bayes_pls_golite062009 |
| N-succinyltransferase activity | 1.81799375593294 | bayes_pls_golite062009 |
| threonine aldolase activity | 1.80396420390785 | bayes_pls_golite062009 |
| adenosylmethionine-8-amino-7-oxononanoate transaminase activity | 1.74778109525713 | bayes_pls_golite062009 |
| glycine dehydrogenase (decarboxylating) activity | 1.63055151623667 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 1.63055151623667 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 1.19150094103499 | bayes_pls_golite062009 |
| transcription regulator activity | 1.07873942461292 | bayes_pls_golite062009 |
| glycine C-acetyltransferase activity | 0.935794708043259 | bayes_pls_golite062009 |
| DNA binding | 0.886628214497634 | bayes_pls_golite062009 |
| nucleic acid binding | 0.814403324199462 | bayes_pls_golite062009 |
| structural molecule activity | 0.754675308623467 | bayes_pls_golite062009 |
| carbon-sulfur lyase activity | 0.698312655247044 | bayes_pls_golite062009 |
| binding | 0.661198018681765 | bayes_pls_golite062009 |
| intramolecular transferase activity, transferring amino groups | 0.659071155545801 | bayes_pls_golite062009 |
| transcription factor activity | 0.615294010373048 | bayes_pls_golite062009 |
| cystathionine beta-lyase activity | 0.15938456446406 | bayes_pls_golite062009 |
| sulfurtransferase activity | 0.0450490929307473 | bayes_pls_golite062009 |
|
Region A: Residues: [67-121] |
1 11 21 31 41 51
| | | | | |
1 QESGFDYEGL IDSELQKKRL DKSYRYFNNI NRLAKEFPLA HRQREADKVT VWCSN
|
|
Region B: Residues: [393-548] |
1 11 21 31 41 51
| | | | | |
1 SQQKHTMYVK KAFHELGIPV IPNPSHIVPV LIGNADLAKQ ASDILINKHQ IYVQAINFPT 60
61 VARGTERLRI TPTPGHTNDL SDILINAVDD VFNELQLPRV RDWESQGGLL GVGESGFVEE 120
121 SNLWTSSQLS LTNDDLNPNV RDPIVKQLEV SSGIKQ
|
| Detection Method: | |
| Confidence: | 570.512579 |
| Match: | 1fc4A_ |
| Description: | 2-amino-3-ketobutyrate CoA ligase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [122-392] |
1 11 21 31 41 51
| | | | | |
1 DYLALSKHPE VLDAMHKTID KYGCGAGGTR NIAGHNIPTL NLEAELATLH KKEGALVFSS 60
61 CYVANDAVLS LLGQKMKDLV IFSDELNHAS MIVGIKHANV KKHIFKHNDL NELEQLLQSY 120
121 PKSVPKLIAF ESVYSMAGSV ADIEKICDLA DKYGALTFLD EVHAVGLYGP HGAGVAEHCD 180
181 FESHRASGIA TPKTNDKGGA KTVMDRVDMI TGTLGKSFGS VGGYVAASRK LIDWFRSFAP 240
241 GFIFTTTLPP SVMAGATAAI RYQRCHIDLR T
|
| Detection Method: | |
| Confidence: | 570.512579 |
| Match: | 1fc4A_ |
| Description: | 2-amino-3-ketobutyrate CoA ligase |
| Matching Structure (courtesy of the PDB): |
|
