| Protein: | HEM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 548 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEM1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..548] | [1..548] |
|
|
0.0 | [6..546] | [14..562] |
|
|
0.0 | [27..547] | [54..569] |
|
|
0.0 | [8..528] | [70..602] |
|
|
0.0 | [10..527] | [74..603] |
|
|
0.0 | [2..489] | [69..540] |
|
|
0.0 | [20..534] | [42..560] |
|
|
0.0 | [36..527] | [6..484] |
|
|
0.0 | [10..498] | [65..549] |
|
|
0.0 | [32..490] | [99..541] |
|
Region A: Residues: [1-66] |
1 11 21 31 41 51
| | | | | |
1 MQRSIFARFG NSSAAVSTLN RLSTTAAPHA KNGYATATGA GAAAATATAS STHAAAAAAA 60
61 AANHST
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.574 | a.4.1 | Homeodomain-like |
| View | Download | 0.696 | a.2.7 | tRNA-binding arm |
| View | Download | 0.777 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.691 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.689 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.537 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.497 | a.4.1 | Homeodomain-like |
| View | Download | 0.451 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.425 | a.4.1 | Homeodomain-like |
| View | Download | 0.424 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.407 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.399 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.398 | a.159.2 | FF domain |
| View | Download | 0.389 | a.3.1 | Cytochrome c |
| View | Download | 0.389 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.383 | d.58.17 | Metal-binding domain |
| View | Download | 0.368 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.360 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.360 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.347 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.346 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.343 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.333 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.327 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.316 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.315 | a.112.1 | Description not found. |
| View | Download | 0.311 | a.5.3 | N-terminal domain of phosphatidylinositol transfer protein sec14p |
| View | Download | 0.309 | a.112.1 | Description not found. |
| View | Download | 0.302 | a.112.1 | Description not found. |
| View | Download | 0.300 | a.77.1 | DEATH domain |
| View | Download | 0.288 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.286 | a.74.1 | Cyclin-like |
| View | Download | 0.286 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.284 | a.39.1 | EF-hand |
| View | Download | 0.283 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.280 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.275 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.272 | a.5.2 | UBA-like |
| View | Download | 0.254 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.253 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.248 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.245 | c.47.1 | Thioredoxin-like |
| View | Download | 0.241 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.241 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.232 | a.2.3 | Chaperone J-domain |
| View | Download | 0.232 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.229 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.221 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.219 | a.39.1 | EF-hand |
| View | Download | 0.217 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.208 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.203 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.202 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.201 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.200 | a.35.1 | lambda repressor-like DNA-binding domains |
| Term | Confidence | Notes |
| L-aspartate:2-oxoglutarate aminotransferase activity | 3.359406422625 | bayes_pls_golite062009 |
| 5-aminolevulinate synthase activity | 3.15163480353521 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| transferase activity | 1.88724762473867 | bayes_pls_golite062009 |
| N-succinyltransferase activity | 1.81799375593294 | bayes_pls_golite062009 |
| threonine aldolase activity | 1.80396420390785 | bayes_pls_golite062009 |
| adenosylmethionine-8-amino-7-oxononanoate transaminase activity | 1.74778109525713 | bayes_pls_golite062009 |
| glycine dehydrogenase (decarboxylating) activity | 1.63055151623667 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 1.63055151623667 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 1.19150094103499 | bayes_pls_golite062009 |
| transcription regulator activity | 1.07873942461292 | bayes_pls_golite062009 |
| glycine C-acetyltransferase activity | 0.935794708043259 | bayes_pls_golite062009 |
| DNA binding | 0.886628214497634 | bayes_pls_golite062009 |
| nucleic acid binding | 0.814403324199462 | bayes_pls_golite062009 |
| structural molecule activity | 0.754675308623467 | bayes_pls_golite062009 |
| carbon-sulfur lyase activity | 0.698312655247044 | bayes_pls_golite062009 |
| binding | 0.661198018681765 | bayes_pls_golite062009 |
| intramolecular transferase activity, transferring amino groups | 0.659071155545801 | bayes_pls_golite062009 |
| transcription factor activity | 0.615294010373048 | bayes_pls_golite062009 |
| cystathionine beta-lyase activity | 0.15938456446406 | bayes_pls_golite062009 |
| sulfurtransferase activity | 0.0450490929307473 | bayes_pls_golite062009 |
|
Region A: Residues: [67-121] |
1 11 21 31 41 51
| | | | | |
1 QESGFDYEGL IDSELQKKRL DKSYRYFNNI NRLAKEFPLA HRQREADKVT VWCSN
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Region B: Residues: [393-548] |
1 11 21 31 41 51
| | | | | |
1 SQQKHTMYVK KAFHELGIPV IPNPSHIVPV LIGNADLAKQ ASDILINKHQ IYVQAINFPT 60
61 VARGTERLRI TPTPGHTNDL SDILINAVDD VFNELQLPRV RDWESQGGLL GVGESGFVEE 120
121 SNLWTSSQLS LTNDDLNPNV RDPIVKQLEV SSGIKQ
|
| Detection Method: | |
| Confidence: | 570.512579 |
| Match: | 1fc4A_ |
| Description: | 2-amino-3-ketobutyrate CoA ligase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [122-392] |
1 11 21 31 41 51
| | | | | |
1 DYLALSKHPE VLDAMHKTID KYGCGAGGTR NIAGHNIPTL NLEAELATLH KKEGALVFSS 60
61 CYVANDAVLS LLGQKMKDLV IFSDELNHAS MIVGIKHANV KKHIFKHNDL NELEQLLQSY 120
121 PKSVPKLIAF ESVYSMAGSV ADIEKICDLA DKYGALTFLD EVHAVGLYGP HGAGVAEHCD 180
181 FESHRASGIA TPKTNDKGGA KTVMDRVDMI TGTLGKSFGS VGGYVAASRK LIDWFRSFAP 240
241 GFIFTTTLPP SVMAGATAAI RYQRCHIDLR T
|
| Detection Method: | |
| Confidence: | 570.512579 |
| Match: | 1fc4A_ |
| Description: | 2-amino-3-ketobutyrate CoA ligase |
| Matching Structure (courtesy of the PDB): |
|
