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View Structure Prediction Details

Protein: PCF11
Organism: Saccharomyces cerevisiae
Length: 626 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCF11.

Description E-value Query
Range
Subject
Range
PCF11 - mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA)...
PCF11_YEAST - Protein PCF11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCF11 PE=1 SV=2
0.0 [1..626] [1..626]
YD14_SCHPO - Uncharacterized protein C4G9.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC4G9.0...
SPAC4G9.04c - cleavage and polyadenylation specificity factor
0.0 [11..620] [7..575]
PCFS1_ARATH - Polyadenylation and cleavage factor homolog 1 OS=Arabidopsis thaliana GN=PCFS1 PE=1 SV=1
6.0E-86 [224..605] [36..392]
gi|18642418 - gi|18642418|emb|CAC81237.1| putative PCF11 protein [Brassica napus]
3.0E-85 [236..609] [38..365]
gi|13435542 - gi|13435542|gb|AAH04648.1| Pcf11 protein [Mus musculus]
1.0E-83 [153..618] [61..488]
gi|6069478 - gi|6069478|dbj|BAA85453.1| S-locus protein 4 [Brassica rapa]
4.0E-81 [236..609] [38..401]
PCF11 - PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
3.0E-78 [153..618] [1157..1596]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHDTEVIVK DFNSILEELT FNSRPIITTL TKLAEENISC AQYFVDAIES RIEKCMPKQK  60
   61 LYAFYALDSI CKNVGSPYTI YFSRNLFNLY KRTYLLVDNT TRTKLINMFK LWLNPND

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 3.44539235794744 bayes_pls_golite062009
transcription regulator activity 2.34092044533955 bayes_pls_golite062009
protein binding 1.97365365208963 bayes_pls_golite062009
nucleic acid binding 1.74252996786746 bayes_pls_golite062009
DNA binding 1.73786982174918 bayes_pls_golite062009
transcription factor activity 1.0565013251721 bayes_pls_golite062009
clathrin binding 0.196939581490181 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [118-460]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGLPLFEGSA LEKIEQFLIK ASALHQKNLQ AMLPTPTVPL LLRDIDKLTC LTSERLKNQP  60
   61 NDEKLKMKLL VLSQLKQELK REKLTLNALK QVQMQLRQVF SQDQQVLQER MRYHELQQQQ 120
  121 QQQQQQQQQQ QQQQQQYHET KDMVGSYTQN SNSAIPLFGN NSDTTNQQNS LSSSLFGNIS 180
  181 GVESFQEIEK KKSLNKINNL YASLKAEGLI YTPPKESIVT LYKKLNGHSN YSLDSHEKQL 240
  241 MKNLPKIPLL NDILSDCKAY FATVNIDVLN NPSLQLSEQT LLQENPIVQN NLIHLLYRSK 300
  301 PNKCSVCGKR FGNSESEKLL QNEHLDWHFR INTRIKGSQN TAN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [461-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGISNSNLNT TTTRKNIQSR NWYLSDSQWA AFKDDEITST KHKNDYTDPH ANKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [515-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDKSALNIHA DENDEGSVDN TLGSDRSNEL EIRGKYVVVP ETSQDMAFKC PICKETVTGV  60
   61 YDEESGEWVW KNTIEVNGKY FHSTCYHETS QNSSKSNSGK VGLDDLKKLV TK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle