| Protein: | GCD6 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 712 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCD6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..704] | [1..704] |
|
|
0.0 | [7..704] | [5..714] |
|
|
0.0 | [2..711] | [15..716] |
|
|
0.0 | [2..701] | [16..711] |
|
|
0.0 | [14..703] | [5..667] |
|
|
0.0 | [65..701] | [1..631] |
|
|
0.0 | [24..704] | [6..659] |
|
Region A: Residues: [1-299] |
1 11 21 31 41 51
| | | | | |
1 MAGKKGQKKS GLGNHGKNSD MDVEDRLQAV VLTDSYETRF MPLTAVKPRC LLPLANVPLI 60
61 EYTLEFLAKA GVHEVFLICS SHANQINDYI ENSKWNLPWS PFKITTIMSP EARCTGDVMR 120
121 DLDNRGIITG DFILVSGDVL TNIDFSKMLE FHKKMHLQDK DHISTMCLSK ASTYPKTRTI 180
181 EPAAFVLDKS TSRCIYYQDL PLPSSREKTS IQIDPELLDN VDEFVIRNDL IDCRIDICTS 240
241 HVPLIFQENF DYQSLRTDFV KGVISSDILG KHIYAYLTDE YAVRVESWQT YDTISQDFL
|
| Detection Method: |  |
| Confidence: | 116.917458 |
| Match: | 1hv9A_ |
| Description: | N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| uridylyltransferase activity | 3.74072767898515 | bayes_pls_golite062009 |
| transferase activity, transferring hexosyl groups | 2.70047942699289 | bayes_pls_golite062009 |
| UTP:glucose-1-phosphate uridylyltransferase activity | 2.65167602524122 | bayes_pls_golite062009 |
| UTP-monosaccharide-1-phosphate uridylyltransferase activity | 2.46432078102948 | bayes_pls_golite062009 |
| UDP-glycosyltransferase activity | 2.33861720107822 | bayes_pls_golite062009 |
| transferase activity | 2.17535315350752 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 2.00651267140641 | bayes_pls_golite062009 |
| catalytic activity | 1.88676710996045 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.49149681135671 | bayes_pls_golite062009 |
| acetylgalactosaminyltransferase activity | 1.33788133706753 | bayes_pls_golite062009 |
| acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity | 1.17181714897181 | bayes_pls_golite062009 |
| polypeptide N-acetylgalactosaminyltransferase activity | 1.10309252319727 | bayes_pls_golite062009 |
| binding | 1.09657219604879 | bayes_pls_golite062009 |
| mannosyltransferase activity | 0.91123217364068 | bayes_pls_golite062009 |
| transferase activity, transferring glycosyl groups | 0.897978517422275 | bayes_pls_golite062009 |
| acyltransferase activity | 0.741838450922005 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups other than amino-acyl groups | 0.717805296858439 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 0.555398952276587 | bayes_pls_golite062009 |
| UDP-N-acetylglucosamine diphosphorylase activity | 0.513376694534047 | bayes_pls_golite062009 |
| O-acyltransferase activity | 0.319932817519902 | bayes_pls_golite062009 |
| mannose-phosphate guanylyltransferase activity | 0.2363835251362 | bayes_pls_golite062009 |
| cytidylyltransferase activity | 0.218759888732981 | bayes_pls_golite062009 |
| guanylyltransferase activity | 0.0539392112504681 | bayes_pls_golite062009 |
|
Region A: Residues: [300-516] |
1 11 21 31 41 51
| | | | | |
1 GRWCYPLVLD SNIQDDQTYS YESRHIYKEK DVVLAQSCKI GKCTAIGSGT KIGEGTKIEN 60
61 SVIGRNCQIG ENIRIKNSFI WDDCIIGNNS IIDHSLIASN ATLGSNVRLN DGCIIGFNVK 120
121 IDDNMDLDRN TKISASPLKN AGSRMYDNES NEQFDQDLDD QTLAVSIVGD KGVGYIYESE 180
181 VSDDEDSSTE ACKEINTLSN QLDELYLSDD SISSATK
|
| Detection Method: | |
| Confidence: | 116.917458 |
| Match: | 1hv9A_ |
| Description: | N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| translation initiation factor activity | 9.37171190530754 | bayes_pls_golite062009 |
| translation regulator activity | 5.35226950142169 | bayes_pls_golite062009 |
| binding | 3.0667965351474 | bayes_pls_golite062009 |
| nucleic acid binding | 2.34284977509828 | bayes_pls_golite062009 |
| transcription regulator activity | 1.76231475025891 | bayes_pls_golite062009 |
| protein binding | 1.73688475473996 | bayes_pls_golite062009 |
| RNA cap binding | 1.73309326409609 | bayes_pls_golite062009 |
| DNA binding | 1.62032607987786 | bayes_pls_golite062009 |
| transcription factor activity | 0.923253759652909 | bayes_pls_golite062009 |
| structural molecule activity | 0.908029258648777 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.803700928110921 | bayes_pls_golite062009 |
| mRNA binding | 0.46864854653143 | bayes_pls_golite062009 |
| RNA binding | 0.40024158562931 | bayes_pls_golite062009 |
| transcription activator activity | 0.0232727461674547 | bayes_pls_golite062009 |
|
Region A: Residues: [517-626] |
1 11 21 31 41 51
| | | | | |
1 KTKKRRTMSV NSIYTDREEI DSEFEDEDFE KEGIATVERA MENNHDLDTA LLELNTLRMS 60
61 MNVTYHEVRI ATITALLRRV YHFIATQTLG PKDAVVKVFN QWGLLFKRQA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.766 | a.1.1 | Globin-like |
| View | Download | 0.704 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.663 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.631 | a.64.1 | Saposin |
| View | Download | 0.616 | a.46.1 | Methionine synthase domain |
| View | Download | 0.616 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.608 | a.24.3 | Cytochromes |
| View | Download | 0.604 | a.4.1 | Homeodomain-like |
| View | Download | 0.599 | a.112.1 | Description not found. |
| View | Download | 0.553 | d.110.4 | SNARE-like |
| View | Download | 0.534 | a.141.1 | Frizzled cystein-rich domain |
| View | Download | 0.531 | d.6.1 | Prion-like |
| View | Download | 0.528 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.526 | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.525 | a.1.1 | Globin-like |
| View | Download | 0.519 | a.5.3 | N-terminal domain of phosphatidylinositol transfer protein sec14p |
| View | Download | 0.516 | a.68.1 | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain |
| View | Download | 0.514 | a.64.1 | Saposin |
| View | Download | 0.509 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.478 | a.26.1 | 4-helical cytokines |
| View | Download | 0.464 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.452 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.450 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.445 | a.130.1 | Chorismate mutase II |
| View | Download | 0.445 | a.24.4 | Hemerythrin |
| View | Download | 0.443 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.433 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.429 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.406 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.401 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.383 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.381 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.380 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.367 | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.363 | a.4.1 | Homeodomain-like |
| View | Download | 0.358 | a.74.1 | Cyclin-like |
| View | Download | 0.356 | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.356 | c.47.1 | Thioredoxin-like |
| View | Download | 0.346 | a.3.1 | Cytochrome c |
| View | Download | 0.338 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.335 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.335 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.333 | a.29.2 | Bromodomain |
| View | Download | 0.330 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.329 | d.150.1 | 4'-phosphopantetheinyl transferase |
| View | Download | 0.325 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.323 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.318 | a.3.1 | Cytochrome c |
| View | Download | 0.316 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.316 | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.306 | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.305 | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.305 | a.39.1 | EF-hand |
| View | Download | 0.303 | a.64.1 | Saposin |
| View | Download | 0.301 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.296 | e.37.1 | Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains |
| View | Download | 0.294 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.293 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.289 | a.59.1 | PAH2 domain |
| View | Download | 0.288 | d.58.34 | Formiminotransferase domain of formiminotransferase-cyclodeaminase. |
| View | Download | 0.285 | a.1.1 | Globin-like |
| View | Download | 0.282 | d.189.1 | PX domain |
| View | Download | 0.276 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.272 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.268 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.267 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.261 | a.74.1 | Cyclin-like |
| View | Download | 0.260 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.258 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.254 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.251 | d.95.2 | Homing endonucleases |
| View | Download | 0.249 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.248 | a.74.1 | Cyclin-like |
| View | Download | 0.247 | a.54.1 | Domain of early E2A DNA-binding protein, ADDBP |
| View | Download | 0.243 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.242 | f.1.5 | Exotoxin A, middle domain |
| View | Download | 0.241 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.238 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.235 | a.47.2 | t-snare proteins |
| View | Download | 0.234 | a.134.1 | Fungal elicitin |
| View | Download | 0.232 | c.55.7 | Methylated DNA-protein cysteine methyltransferase domain |
| View | Download | 0.229 | a.118.8 | TPR-like |
| View | Download | 0.229 | a.79.1 | Antitermination factor NusB |
| View | Download | 0.229 | a.149.1 | RNase III endonuclease catalytic domain |
| View | Download | 0.227 | d.58.21 | Molybdenum cofactor biosynthesis protein C, MoaC |
| View | Download | 0.225 | a.74.1 | Cyclin-like |
| View | Download | 0.220 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.220 | a.24.3 | Cytochromes |
| View | Download | 0.219 | a.39.1 | EF-hand |
| View | Download | 0.217 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.215 | a.39.1 | EF-hand |
| View | Download | 0.214 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.214 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.212 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.211 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.209 | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.204 | a.135.1 | Tetraspanin |
| View | Download | 0.202 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.201 | a.48.1 | N-terminal domain of cbl (N-cbl) |
|
Region A: Residues: [627-712] |
1 11 21 31 41 51
| | | | | |
1 FDEEEYIDLM NIIMEKIVEQ SFDKPDLILF SALVSLYDND IIEEDVIYKW WDNVSTDPRY 60
61 DEVKKLTVKW VEWLQNADEE SSSEEE
|
| Detection Method: | |
| Confidence: | 27.60206 |
| Match: | PF02020 |
| Description: | eIF4-gamma/eIF5/eIF2-epsilon |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
