






| Protein: | HMO1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 246 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMO1.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-44 | [4..227] | [5..234] |
|
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1.0E-44 | [4..227] | [5..229] |
|
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4.0E-44 | [4..227] | [5..232] |
|
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7.0E-44 | [4..227] | [5..232] |
|
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9.0E-44 | [4..227] | [5..232] |
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1.0E-43 | [4..227] | [5..232] |
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1.0E-43 | [4..227] | [5..232] |
|
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1.0E-43 | [4..227] | [5..229] |
|
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2.0E-43 | [4..227] | [5..232] |
|
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2.0E-43 | [4..227] | [5..232] |
|
Region A: Residues: [1-92] |
1 11 21 31 41 51
| | | | | |
1 MTTDPSVKLK SAKDSLVSSL FELSKAANQT ASSIVDFYNA IGDDEEEKIE AFTTLTESLQ 60
61 TLTSGVNHLH GISSELVNPI DDDKDAIIAA PV
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.932 | 0.014 | RNA polymerase I transcription factor activity | a.7.5 | Tubulin chaperone cofactor A |
|
Region A: Residues: [93-246] |
1 11 21 31 41 51
| | | | | |
1 KAVRRKIERD PNAPKKPLTV FFAYSAYVRQ ELREDRQKAG LPPLSSTEIT QEISKKWKEL 60
61 SDNEKEKWKQ AYNVELENYQ REKSKYLEAK KNGTLPPASL ENGPTHAPVP IPFSLQHAAE 120
121 PPVEKRPHDD DGSSEKKKKK KKKDKKKDKS NSSI
|
| Detection Method: | |
| Confidence: | 44.325697 |
| Match: | 1k99A_ |
| Description: | Upstream binding factor |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| DNA binding | 5.15324651287773 | bayes_pls_golite062009 |
| nucleic acid binding | 5.01228762819617 | bayes_pls_golite062009 |
| transcription regulator activity | 4.9607192917135 | bayes_pls_golite062009 |
| transcription factor activity | 3.82658263870186 | bayes_pls_golite062009 |
| binding | 3.6211482127468 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.96229555092695 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.75319687398598 | bayes_pls_golite062009 |
| chromatin binding | 1.64428658020027 | bayes_pls_golite062009 |
| transcription activator activity | 1.62744929149746 | bayes_pls_golite062009 |
| transcription repressor activity | 1.53825678633232 | bayes_pls_golite062009 |
| protein binding | 1.131658134984 | bayes_pls_golite062009 |
| transcription factor binding | 1.10315330167937 | bayes_pls_golite062009 |
| DNA bending activity | 0.87985209274756 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.261169200304829 | bayes_pls_golite062009 |
| RNA polymerase I transcription factor activity | 0.0772111539778018 | bayes_pls_golite062009 |