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View Structure Prediction Details

Protein: TAF10
Organism: Saccharomyces cerevisiae
Length: 206 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF10.

Description E-value Query
Range
Subject
Range
TAF10 - Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiatio...
gi|151942149 - gi|151942149|gb|EDN60505.1| TFIID subunit [Saccharomyces cerevisiae YJM789]
TAF10_YEAST - Transcription initiation factor TFIID subunit 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
gi|207346649 - gi|207346649|gb|EDZ73087.1| YDR167Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190404879 - gi|190404879|gb|EDV08146.1| transcription initiation factor TFIID subunit 10 [Saccharomyces cerevisi...
4.0E-68 [1..206] [1..206]
gi|220942412, gi... - gi|220952646|gb|ACL88866.1| Taf10-PA [synthetic construct], gi|220942412|gb|ACL83749.1| Taf10-PA [sy...
Taf10-PA - The gene TBP-associated factor 10 is referred to in FlyBase by the symbol Dmel\Taf10 (CG2859, FBgn00...
5.0E-49 [21..205] [11..166]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-40 [74..205] [116..218]
gi|61363275, gi|... - gi|61363578|gb|AAX42413.1| TAF10 RNA polymerase II TATA box binding protein-associated factor [synth...
TAF10 - TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
2.0E-40 [74..205] [116..217]
gi|16944608 - gi|16944608|emb|CAC28563.2| related to transcription factor TAF25 [Neurospora crassa]
7.0E-37 [56..206] [46..211]
TAF10_SCHPO - Transcription initiation factor TFIID subunit 10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...
taf10 - transcription factor TFIID complex subunit Taf10
4.0E-36 [8..206] [19..215]
gi|19074883, gi|... - gi|19074883|ref|NP_586389.1| similarity to TRANSCRIPTION INITIATION FACTOR TFIID 30kDa SUBUNIT [Ence...
gi|19074883 - gi|19074883|ref|NP_586389.1| similarity to TRANSCRIPTION INITIATION FACTOR TFIID 30kDa SUBUNIT [Ence...
2.0E-32 [70..205] [27..132]
TAF10_ARATH - Transcription initiation factor TFIID subunit 10 OS=Arabidopsis thaliana GN=TAF10 PE=1 SV=1
2.0E-30 [71..205] [15..119]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR EAVVDDGSEN  60
   61 AFGIPE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.354 d.50.1 dsRNA-binding domain-like
View Download 0.312 a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.234 a.2.3 Chaperone J-domain
View Download 0.284 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.266 a.5.4 Elongation factor TFIIS domain 2
View Download 0.220 a.64.1 Saposin
View Download 0.217 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.214 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.210 a.64.1 Saposin
View Download 0.209 f.13.1 Family A G protein-coupled receptor-like
View Download 0.209 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 8.88482968293417 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
histone acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
N-acetyltransferase activity 4.49084162254966 bayes_pls_golite062009
DNA binding 4.24660531286828 bayes_pls_golite062009
N-acyltransferase activity 4.2172829451557 bayes_pls_golite062009
nucleic acid binding 4.14026521609645 bayes_pls_golite062009
transcription regulator activity 3.91807454227165 bayes_pls_golite062009
acetyltransferase activity 3.91533222675137 bayes_pls_golite062009
transcription initiation factor activity 3.78067108255869 bayes_pls_golite062009
acyltransferase activity 3.38996237245502 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.35419529667223 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.18312128320637 bayes_pls_golite062009
binding 3.14832737946099 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.02428691626433 bayes_pls_golite062009
transcription factor activity 2.39322722597434 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.83714729861923 bayes_pls_golite062009
transcription activator activity 1.12739348005764 bayes_pls_golite062009
nucleotidyltransferase activity 1.03060091158028 bayes_pls_golite062009
protein binding 1.01897642648285 bayes_pls_golite062009
transcription factor binding 1.01773884290535 bayes_pls_golite062009
transcription coactivator activity 0.976797801726735 bayes_pls_golite062009
transcription cofactor activity 0.840442755533537 bayes_pls_golite062009
transcription repressor activity 0.621482805601238 bayes_pls_golite062009
histone binding 0.184823910505751 bayes_pls_golite062009
sequence-specific DNA binding 0.0585868733603467 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [67-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTRKDKTLEE ILEMMDSTPP IIPDAVIDYY LTKNGFNVAD VRVKRLLALA TQKFVSDIAK  60
   61 DAYEYSRIRS SVAVSNANNS QARARQLLQG QQQPGVQQIS QQQHQQNEKT TASKVVLTVN 120
  121 DLSSAVAEYG LNIGRPDFYR 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 36.619789
Match: PF03540
Description: Transcription initiation factor TFIID 23-30kDa subunit

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle