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View Structure Prediction Details

Protein: PAA1
Organism: Saccharomyces cerevisiae
Length: 191 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAA1.

Description E-value Query
Range		 Subject
Range
gi|207346780 - gi|207346780|gb|EDZ73175.1| YDR071Cp-like protein [Saccharomyces cerevisiae AWRI1631]
PAA1_YEAST - Polyamine N-acetyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PAA1 PE=...
gi|151942060 - gi|151942060|gb|EDN60416.1| polyamine acetyltransferase [Saccharomyces cerevisiae YJM789]
gi|190404961 - gi|190404961|gb|EDV08228.1| polyamine acetyltransferase [Saccharomyces cerevisiae RM11-1a]
PAA1 - Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also ...
 1.0E-34 [1..191] [1..191]
SNAT_MOUSE - Serotonin N-acetyltransferase OS=Mus musculus GN=Aanat PE=2 SV=1
 2.0E-27 [7..174] [29..188]
SNAT_MESAU - Serotonin N-acetyltransferase OS=Mesocricetus auratus GN=AANAT PE=2 SV=1
 4.0E-27 [7..174] [31..190]
SNAT_BOVIN - Serotonin N-acetyltransferase OS=Bos taurus GN=AANAT PE=1 SV=1
 1.0E-26 [7..175] [31..191]
SNAT_RAT - Serotonin N-acetyltransferase OS=Rattus norvegicus GN=Aanat PE=1 SV=1
 3.0E-26 [7..174] [29..188]
SNAT_SHEEP - Serotonin N-acetyltransferase OS=Ovis aries GN=AANAT PE=1 SV=1
 4.0E-26 [7..175] [31..191]
gi|14278224, gi|... - gi|14278225|pdb|1IB1|H Chain H, Crystal Structure Of The 14-3-3 Zeta:serotonin N- Acetyltransferase ...
gi|14278225|pdb|... - Chain G, Crystal Structure Of The 14-3-3 Zeta:serotonin N- Acetyltransferase Complex, Chain F, Cryst...
 7.0E-26 [8..175] [31..190]
SNAT_CHICK - Serotonin N-acetyltransferase OS=Gallus gallus GN=AANAT PE=2 SV=1
 3.0E-25 [7..177] [29..191]

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Predicted Domain #1
Region A:
Residues: [1-191] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSSSTLPL HMYIRPLIIE DLKQILNLES QGFPPNERAS EEIISFRLIN CPELCSGLFI  60
   61 REIEGKEVKK ETLIGHIMGT KIPHEYITIE SMGKLQVESS NHIGIHSVVI KPEYQKKNLA 120
  121 TLLLTDYIQK LSNQEIGNKI VLIAHEPLIP FYERVGFKII AENTNVAKDK NFAEQKWIDM 180
  181 ERELIKEEYD N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.9691
Match: 1kuvA_
Description: Serotonin N-acetyltranferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
N-acyltransferase activity 3.21568934984495 bayes_pls_golite062009
N-acetyltransferase activity 3.08034095767905 bayes_pls_golite062009
histone acetyltransferase activity 3.04157204238388 bayes_pls_golite062009
lysine N-acetyltransferase activity 3.04157204238388 bayes_pls_golite062009
acetyltransferase activity 2.84289106846615 bayes_pls_golite062009
catalytic activity 1.97933499002461 bayes_pls_golite062009
transferase activity 1.72447231774431 bayes_pls_golite062009
diamine N-acetyltransferase activity 1.61977223570735 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.42711272311757 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 1.24328242407788 bayes_pls_golite062009
acyltransferase activity 1.2338745976101 bayes_pls_golite062009
0.717135555516362 bayes_pls_golite062009
transcription factor binding 0.61516943067272 bayes_pls_golite062009
ornithine decarboxylase regulator activity 0.455783614765891 bayes_pls_golite062009
binding 0.437605892967756 bayes_pls_golite062009
ornithine decarboxylase inhibitor activity 0.412837976409128 bayes_pls_golite062009
protein binding 0.283213965640071 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle