| Protein: | HO |
| Organism: | Saccharomyces cerevisiae |
| Length: | 586 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HO.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..586] | [1..586] |
|
|
0.0 | [1..586] | [1..586] |
|
|
0.0 | [1..586] | [1..586] |
|
|
0.0 | [1..586] | [1..586] |
|
|
0.0 | [3..467] | [31..484] |
|
Region A: Residues: [1-56] |
1 11 21 31 41 51
| | | | | |
1 MLSENTTILM ANGEIKDIAN VTANSYVMCA DGSAARVINV TQGYQKIYNI QQKTKH
|
|
Region B: Residues: [72-186] |
1 11 21 31 41 51
| | | | | |
1 TVYQRLALQC TAGHKLSVRV PTKPLLEKSG RNATKYKVRW RNLQQCQTLD GRIIIIPKNH 60
61 HKTFPMTVEG EFAAKRFIEE MERSKGEYFN FDIEVRDLDY LDAQLRISSC IRFGP
|
|
Region C: Residues: [429-471] |
1 11 21 31 41 51
| | | | | |
1 PVYFSFTDDF QGESTVYGLT IEGHKNFLLG NKIEVKSCRG CCV
|
| Detection Method: |  |
| Confidence: | 634.221849 |
| Match: | 1ef0A_ |
| Description: | VMA1-derived endonuclease (VDE) PI-Scei intein; VMA1-derived endonuclease (VDE) PI-SceI |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| endonuclease activity | 2.88774834271613 | bayes_pls_golite062009 |
| hydrolase activity | 1.79906089282626 | bayes_pls_golite062009 |
| nucleic acid binding | 1.69943842528394 | bayes_pls_golite062009 |
| nuclease activity | 1.69431538580197 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.67894659587491 | bayes_pls_golite062009 |
| binding | 1.37674270036607 | bayes_pls_golite062009 |
| DNA binding | 1.16190065301609 | bayes_pls_golite062009 |
| catalytic activity | 1.00294942392567 | bayes_pls_golite062009 |
|
Region A: Residues: [57-71] |
1 11 21 31 41 51
| | | | | |
1 RAFEGEPGRL DPRRR
|
|
Region B: Residues: [187-428] |
1 11 21 31 41 51
| | | | | |
1 VLAGNGVLSK FLTGRSDLVT PAVKSMAWML GLWLGDSTTK EPEISVDSLD PKLMESLREN 60
61 AKIWGLYLTV CDDHVPLRAK HVRLHYGDGP DENRKTRNLR KNNPFWKAVT ILKFKRDLDG 120
121 EKQIPEFMYG EHIEVREAFL AGLIDSDGYV VKKGEGPESY KIAIQTVYSS IMDGIVHISR 180
181 SLGMSATVTT RSAREEIIEG RKVQCQFTYD CNVAGGTTSQ NVLSYCRSGH KTREVPPIIK 240
241 RE
|
| Detection Method: | |
| Confidence: | 634.221849 |
| Match: | 1ef0A_ |
| Description: | VMA1-derived endonuclease (VDE) PI-Scei intein; VMA1-derived endonuclease (VDE) PI-SceI |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 2.74510263950241 | bayes_pls_golite062009 |
| DNA binding | 2.44566855074341 | bayes_pls_golite062009 |
| nucleic acid binding | 2.43961252291181 | bayes_pls_golite062009 |
| binding | 2.27558039325716 | bayes_pls_golite062009 |
| transcription factor activity | 1.9022303099625 | bayes_pls_golite062009 |
| protein binding | 1.32615100395362 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.911347670379084 | bayes_pls_golite062009 |
| transcription activator activity | 0.879128871932985 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.839985608194026 | bayes_pls_golite062009 |
| transcription factor binding | 0.68208034120073 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 0.469723986686757 | bayes_pls_golite062009 |
| catalytic activity | 0.133319360419662 | bayes_pls_golite062009 |
|
Region A: Residues: [472-586] |
1 11 21 31 41 51
| | | | | |
1 GEQLKISQKK NLKHCVACPR KGIKYFYKDW SGKNRVCARC YGRYKFSGHH CINCKYVPEA 60
61 REVKKAKDKG EKLGITPEGL PVKGPECIKC GGILQFDAVR GPHKSCGNNA GARIC
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
