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View Structure Prediction Details

Protein: RDI1
Organism: Saccharomyces cerevisiae
Length: 202 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RDI1.

Description E-value Query
Range
Subject
Range
gi|7245832 - gi|7245832|pdb|1DOA|A Chain A, Structure Of The Rho Family Gtp-Binding Protein Cdc42 In Complex With...
2.0E-80 [1..202] [16..216]
GDIR1_BOVIN - Rho GDP-dissociation inhibitor 1 OS=Bos taurus GN=ARHGDIA PE=1 SV=3
2.0E-80 [1..202] [1..201]
gi|13435747 - gi|13435747|gb|AAH04732.1| Rho GDP dissociation inhibitor (GDI) alpha [Mus musculus]
5.0E-79 [1..202] [1..201]
RDI1 - Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p
GDIR_YEAST - Rho GDP-dissociation inhibitor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RDI1 PE=1...
gi|190405139 - gi|190405139|gb|EDV08406.1| rho GDP-dissociation inhibitor [Saccharomyces cerevisiae RM11-1a]
gi|151941866 - gi|151941866|gb|EDN60222.1| rho GDP dissociation inhibitor [Saccharomyces cerevisiae YJM789]
gi|207347049 - gi|207347049|gb|EDZ73358.1| YDL135Cp-like protein [Saccharomyces cerevisiae AWRI1631]
1.0E-70 [1..202] [1..202]

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Predicted Domain #1
Region A:
Residues: [1-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEESTDFSQ FEEERNNDQY KVSAKKTVDE YKNLDAEDES LAKWKESLGL SSDVLPLEFP  60
   61 GDKRKVVVQK IQLLVNTEPN PITFDLTNEK TIKELASKRY KIKENSIYKL KIVFKVQHEI 120
  121 ITGLRYVQYI KKAGIAVDKI DDHLGSYAPN TKTKPFYEVE LPESEAPSGF LARGNYSAVS 180
  181 KFIDDDKTNH LTLNWGVEIV KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 376.450636
Match: 1doaB_
Description: Rho GDP-dissociation inhibitor 1, RhoGDI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 4.21900602727099 bayes_pls_golite062009
cytoskeletal protein binding 3.82728537491772 bayes_pls_golite062009
voltage-gated cation channel activity 2.79599274364249 bayes_pls_golite062009
voltage-gated ion channel activity 2.7120102542099 bayes_pls_golite062009
voltage-gated channel activity 2.70863932585459 bayes_pls_golite062009
potassium channel activity 2.69685666968196 bayes_pls_golite062009
voltage-gated potassium channel activity 2.69627305312298 bayes_pls_golite062009
binding 2.65544526722793 bayes_pls_golite062009
cation channel activity 2.65302958856525 bayes_pls_golite062009
gated channel activity 2.52278796517374 bayes_pls_golite062009
transporter activity 2.46466249895824 bayes_pls_golite062009
substrate-specific transporter activity 2.37642404692102 bayes_pls_golite062009
transmembrane transporter activity 2.37262306131842 bayes_pls_golite062009
substrate-specific channel activity 2.32502571419352 bayes_pls_golite062009
channel activity 2.3181005726144 bayes_pls_golite062009
passive transmembrane transporter activity 2.3181005726144 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.31677709260544 bayes_pls_golite062009
ion transmembrane transporter activity 2.28077016868353 bayes_pls_golite062009
ion channel activity 2.2553711462771 bayes_pls_golite062009
cation transmembrane transporter activity 2.23522391314947 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.15379228421204 bayes_pls_golite062009
inward rectifier potassium channel activity 1.86598930407084 bayes_pls_golite062009
ligand-gated ion channel activity 1.81486809950722 bayes_pls_golite062009
ligand-gated channel activity 1.81486809950722 bayes_pls_golite062009
Rho GDP-dissociation inhibitor activity 1.67374100547551 bayes_pls_golite062009
actin filament binding 1.67203076960313 bayes_pls_golite062009
small GTPase regulator activity 1.55727555528218 bayes_pls_golite062009
protein binding 1.50286160643298 bayes_pls_golite062009
GTPase regulator activity 1.44225801859996 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.42486878565247 bayes_pls_golite062009
clathrin binding 1.23902179002817 bayes_pls_golite062009
molecular transducer activity 1.12993648323166 bayes_pls_golite062009
signal transducer activity 1.12993648323166 bayes_pls_golite062009
enzyme regulator activity 1.05880190577068 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.580608094701522 bayes_pls_golite062009

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