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View Structure Prediction Details

Protein: PMT1
Organism: Saccharomyces cerevisiae
Length: 817 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PMT1.

Description E-value Query
Range
Subject
Range
PMT1 - Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to prote...
PMT1_YEAST - Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 2...
0.0 [1..817] [1..817]
PMT1_CANAL - Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC ...
PMT1_CANAL - Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Candida albicans GN=PMT1 PE=3 SV=1
0.0 [14..769] [31..789]
gi|14625800 - gi|14625800|gb|AAK71510.1| dolichyl-phosphate-mannose:protein mannosyltransferase [Emericella nidula...
gi|49095562, gi|... - gi|67537870|ref|XP_662709.1| hypothetical protein AN5105.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
0.0 [12..727] [30..736]
gi|32415215, gi|... - gi|9368945|emb|CAB99175.1| probable dolichyl-phosphate-mannose--protein mannosyltransferase [Neurosp...
gi|85079003 - gi|85079003|ref|XP_956270.1| probable dolichyl-phosphate-mannose--protein mannosyltransferase [MIPS]...
0.0 [14..727] [18..744]
gi|15011522 - gi|15011522|gb|AAK77607.1|AF396953_1 protein O-mannosyl transferase [Aspergillus awamori]
0.0 [30..727] [43..737]
PMT1_SCHPO - Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 /...
ogm1 - protein O-mannosyltransferase Ogm1
0.0 [38..774] [22..763]
rt-PA - The gene rotated abdomen is referred to in FlyBase by the symbol Dmel\rt (CG6097, FBgn0003292). It i...
0.0 [20..729] [144..877]
POMT2 - protein-O-mannosyltransferase 2
0.0 [24..729] [22..750]

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Predicted Domain #1
Region A:
Residues: [1-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEKTYKRV EQDDPVPELD IKQGPVRPFI VTDPSAELAS LRTMVTLKEK LLVACLAVFT  60
   61 AVIRLHGLAW PDSVVFDEVH FGGFASQYIR GTYFMDVHPP LAKMLYAGVA SLGGFQGDFD 120
  121 FENIGDSFPS TTPYVLMRFF SASLGALTVI LMYMTLRYSG VRMWVALMSA ICFAVENSYV 180
  181 TISRYILLDA PLMFFIAAAV YSFKKYEMYP ANSLNAYKSL LATGIALGMA SSSKWVGLFT 240
  241 VTWVGLLCIW RLWFMIGDLT KSSKSIFKVA FAKLAFLLGV PFALYLVFFY IHFQSLTLDG 300
  301 DGASFFSPEF RSTLKNNKI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 100.619789
Match: PF02366
Description: Dolichyl-phosphate-mannose-protein mannosyltransferase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [320-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQNVVADVGI GSIISLRHLS TMGGYLHSHS HNYPAGSEQQ QSTLYPHMDA NNDWLLELYN  60
   61 APGES

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 16.0
Match: PF02815
Description: MIR domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [385-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTTFQNLTDG TKVRLFHTVT RCRLHSHDHK PPVSESSDWQ KEVSCYGYSG FDGDANDDWV  60
   61 VEIDKKNSAP GVA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 19.823909
Match: PF02815
Description: MIR domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
dolichyl-phosphate-mannose-protein mannosyltransferase activity 7.33543412640964 bayes_pls_golite062009
mannosyltransferase activity 6.32966341675541 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.60661923349025 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.57555885876017 bayes_pls_golite062009
receptor activity 1.99332745476324 bayes_pls_golite062009
binding 1.86366637427031 bayes_pls_golite062009
molecular transducer activity 1.71523634580131 bayes_pls_golite062009
signal transducer activity 1.71523634580131 bayes_pls_golite062009
cation channel activity 1.66500687404195 bayes_pls_golite062009
ion channel activity 1.61859406934521 bayes_pls_golite062009
substrate-specific channel activity 1.57127083095499 bayes_pls_golite062009
passive transmembrane transporter activity 1.55374970486978 bayes_pls_golite062009
channel activity 1.55374970486978 bayes_pls_golite062009
inositol-1,4,5-trisphosphate receptor activity 1.28298370923705 bayes_pls_golite062009
transferase activity 0.981084601370981 bayes_pls_golite062009
calcium channel activity 0.85901349040585 bayes_pls_golite062009
catalytic activity 0.659936859803906 bayes_pls_golite062009
calcium-release channel activity 0.65133561512386 bayes_pls_golite062009
gated channel activity 0.53737429019655 bayes_pls_golite062009
ligand-gated ion channel activity 0.52162184692236 bayes_pls_golite062009
ligand-gated channel activity 0.52162184692236 bayes_pls_golite062009
protein binding 0.405144403982597 bayes_pls_golite062009
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0.152598505509111 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [458-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QERVIALDTK FRLRHAMTGC YLFSHEVKLP AWGFEQQEVT CASSGRHDLT LWYVENNSNP  60
   61 LLPEDTKRIS YKPASFISKF IESHKKMWHI 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 19.508638
Match: PF02815
Description: MIR domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [548-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKNLVEPHVY ESQPTSWPFL LRGISYWGEN NRNVYLLGNA IVWWAVTAFI GIFGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.960 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac

Predicted Domain #6
Region A:
Residues: [603-743]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVITELFSWQ LGKPILKDSK VVNFHVQVIH YLLGFAVHYA PSFLMQRQMF LHHYLPAYYF  60
   61 GILALGHALD IIVSYVFRSK RQMGYAVVIT FLAASVYFFK SFSPIIYGTP WTQELCQKSQ 120
  121 WLSGWDYNCN TYFSSLEEYK N

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [744-817]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTLTKRESQP AATSTVEEIT IEGDGPSYED LMNEDGKKIF KDTEGNELDP EVVKKMLEEE  60
   61 GANILKVEKR AVLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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