| Protein: | CWH43 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 953 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CWH43.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..953] | [1..953] |
|
|
0.0 | [272..953] | [8..699] |
|
|
0.0 | [272..953] | [8..699] |
|
|
6.0E-97 | [533..952] | [1..424] |
|
|
5.0E-89 | [559..952] | [1..400] |
|
|
7.0E-73 | [1..230] | [14..252] |
|
Region A: Residues: [1-242] |
1 11 21 31 41 51
| | | | | |
1 MLIINGKIIP IAHTICAFSA FFAALVTGYS LHFHKIVTNA HYTYPDEWFP SVSATIGDRY 60
61 PERSIFQILI ALTAFPRFLL LLGHYYLNQS KVCFLVGVLR TVSCGGWVYI TSTDDHDIHD 120
121 IFMITYIVLT LPWDIMITRY SSPLTSKNKG LTATIFFGTL FPMIYWYIQH SVQQRAGAYS 180
181 IYAYFEWSLI LLDIAFDAFA YADFKKIDIV LAFNEKPGNT SFFQIRDSSP INYGEEKSSE 240
241 LQ
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [243-631] |
1 11 21 31 41 51
| | | | | |
1 KSGEKKVEKE KPVARSATGS YFRFDSFFYL LTNIFNGFLF WSNVTSLLCS IWHFPLWYMG 60
61 ISGYEAAILG YLGPIFLYLP FVSEAFTQYG VLLGGIIAIG AYIVQMPELR LISVAVGTSI 120
121 TVATFVQNLR YITNAETSFS FALTWLLGLV ASVILKMGFY TNNPTWVILD ERNGGYNKTA 180
181 LVLTVLFGML SPYVNSINFE GKRNAQAKSA SLIGKLFLAV GFGSLLFGIH QLLTDSSTTI 240
241 YWAWEGYNES HGPLPWPWGA LTCTVMLFAS LSSVKFMGKP LVPCLLLLIS TAVLSARSIT 300
301 QWPKYIFGGL LYAIAMLWLV PSYFSALGQV QNIWVYVLSF SVYIIFVLAH VWVVAYAFVP 360
361 MGWVLREKIE TVLAFSSTFI IIGALTCKN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [632-953] |
1 11 21 31 41 51
| | | | | |
1 LNIQLVTMGK KFFIYVFFFA VALLSLTARF VYDIRPTGIP QPYHPDSQLI TAGIWTIHFG 60
61 LDNDMWASED RMINLIKDME LDVVGLLETD TQRITMGNRD LTSKLAHDLN MYADFGPGPN 120
121 KHTWGCVLLS KFPIVNSTHH LLPSPVGELA PAIHATLQTY NDTLVDVFVF HSGQEEDEED 180
181 RRLQSNYMAK LMGNTTRPAI LLSYLVVDPG EGNYNTYVSE TSGMHDIDPS DDDRWCEYIL 240
241 YRGLRRTGYA RVARGTITDT ELQVGKFQVL SEQALVEHSD SMYEYGHMSE PEYEDMKFPD 300
301 KFLGEGERGH FYHVFDEPRY YL
|
| Detection Method: | |
| Confidence: | 40.39794 |
| Match: | 1hd7A_ |
| Description: | DNA repair endonuclease Hap1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [501-614] |
1 11 21 31 41 51
| | | | | |
1 GALTCTVMLF ASLSSVKFMG KPLVPCLLLL ISTAVLSARS ITQWPKYIFG GLLYAIAMLW 60
61 LVPSYFSALG QVQNIWVYVL SFSVYIIFVL AHVWVVAYAF VPMGWVLREK IETV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [615-953] |
1 11 21 31 41 51
| | | | | |
1 LAFSSTFIII GALTCKNLNI QLVTMGKKFF IYVFFFAVAL LSLTARFVYD IRPTGIPQPY 60
61 HPDSQLITAG IWTIHFGLDN DMWASEDRMI NLIKDMELDV VGLLETDTQR ITMGNRDLTS 120
121 KLAHDLNMYA DFGPGPNKHT WGCVLLSKFP IVNSTHHLLP SPVGELAPAI HATLQTYNDT 180
181 LVDVFVFHSG QEEDEEDRRL QSNYMAKLMG NTTRPAILLS YLVVDPGEGN YNTYVSETSG 240
241 MHDIDPSDDD RWCEYILYRG LRRTGYARVA RGTITDTELQ VGKFQVLSEQ ALVEHSDSMY 300
301 EYGHMSEPEY EDMKFPDKFL GEGERGHFYH VFDEPRYYL
|
| Detection Method: | |
| Confidence: | 44.154902 |
| Match: | 2isiA |
| Description: | No description for 2isiA was found. |
| Term | Confidence | Notes |
| inositol or phosphatidylinositol phosphatase activity | 5.08340215818195 | bayes_pls_golite062009 |
| phosphatidylinositol bisphosphate phosphatase activity | 4.31986043742678 | bayes_pls_golite062009 |
| phosphoinositide 5-phosphatase activity | 4.20326783658706 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | 4.20326783658706 | bayes_pls_golite062009 |
| inositol-polyphosphate 5-phosphatase activity | 2.94523020814127 | bayes_pls_golite062009 |
| inositol trisphosphate phosphatase activity | 2.92493218089814 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.04540265799637 | bayes_pls_golite062009 |
| lipid phosphatase activity | 1.80791721648826 | bayes_pls_golite062009 |
| catalytic activity | 1.76511376991978 | bayes_pls_golite062009 |
| phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity | 1.54959696750258 | bayes_pls_golite062009 |
| phosphatidylinositol-4-phosphate phosphatase activity | 1.54959696750258 | bayes_pls_golite062009 |
| phosphatase activity | 1.49726164551553 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 1.44905138167792 | bayes_pls_golite062009 |
| binding | 1.31660174492743 | bayes_pls_golite062009 |
| phosphatidylinositol trisphosphate phosphatase activity | 0.731013770154616 | bayes_pls_golite062009 |
| phosphatidylinositol-3-phosphatase activity | 0.725138642234872 | bayes_pls_golite062009 |
| nucleic acid binding | 0.652905853950749 | bayes_pls_golite062009 |
| nuclease activity | 0.623968581242132 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 0.620825895803427 | bayes_pls_golite062009 |
| DNA binding | 0.524359544607599 | bayes_pls_golite062009 |
| protein binding | 0.476649214025345 | bayes_pls_golite062009 |
| transcription regulator activity | 0.312330562637603 | bayes_pls_golite062009 |
| hydrolase activity | 0.283637370318741 | bayes_pls_golite062009 |
| exonuclease activity | 0.219613338022829 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.213742479001316 | bayes_pls_golite062009 |
