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View Structure Prediction Details

Protein: HAP3
Organism: Saccharomyces cerevisiae
Length: 144 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAP3.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 8.0E-47 [6..138] [23..153]
ENSMMUT000000317... - null, null
NFYB - nuclear transcription factor Y, beta
ENSCJAT00000028469 - null
gi|123993257, gi... - gi|60656481|gb|AAX32804.1| nuclear transcription factor Y beta [synthetic construct], gi|208966894|d...
 7.0E-46 [6..137] [25..154]
gi|579588|emb|CA... - unnamed protein product [Homo sapiens]
NFYB_RAT - Nuclear transcription factor Y subunit beta OS=Rattus norvegicus GN=Nfyb PE=1 SV=1
NFYB_MOUSE - Nuclear transcription factor Y subunit beta OS=Mus musculus GN=Nfyb PE=1 SV=1
 1.0E-45 [6..137] [25..154]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 2.0E-45 [6..137] [25..154]
NFYB_CHICK - Nuclear transcription factor Y subunit beta OS=Gallus gallus GN=NFYB PE=2 SV=2
 7.0E-45 [6..136] [23..151]
gi|147901227, gi... - gi|3170225|gb|AAC82336.1| nuclear Y/CCAAT-box binding factor B subunit NF-YB [Xenopus laevis], gi|14...
 2.0E-44 [6..136] [23..152]
gi|203355 - gi|203355|gb|AAA40888.1| CCAAT binding transcription factor-B subunit
 2.0E-39 [20..137] [1..116]

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Predicted Domain #1
Region A:
Residues: [1-144] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNESEHVS TSPEDTQENG GNASSSGSLQ QISTLREQDR WLPINNVARL MKNTLPPSAK  60
   61 VSKDAKECMQ ECVSELISFV TSEASDRCAA DKRKTINGED ILISLHALGF ENYAEVLKIY 120
  121 LAKYRQQQAL KNQLMYEQDD EEVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.08661
Match: 1jfiB_
Description: Negative cofactor 2, NC2, beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.24625687315724 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 4.04353148658823 bayes_pls_golite062009
nucleic acid binding 3.93473976418251 bayes_pls_golite062009
binding 3.84636641231951 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
transcription factor activity 2.31114764804139 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
protein binding 0.978906971260821 bayes_pls_golite062009
transcription repressor activity 0.72554769377984 bayes_pls_golite062009
transcription initiation factor activity 0.0945459819298291 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle