| Protein: | HIR1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 840 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIR1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [138..783] | [865..1492] |
|
|
0.0 | [1..840] | [1..840] |
|
|
0.0 | [9..576] | [823..1341] |
|
Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MKVVKFPWLA HREESRKYEI YTVDVSHDGK RLATGGLDGK IRIWSIDSIL RCMELESLTP 60
61 EIPLPQDLQM PLCSMSR
|
| Detection Method: |  |
| Confidence: | 130.67837 |
| Match: | 1gg2B_ |
| Description: | beta1-subunit of the signal-transducing G protein heterotrimer |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [78-130] |
1 11 21 31 41 51
| | | | | |
1 HTGSITCVKF SPDGKYLASG SDDRILLIWA LDEEQSSQPA FGSEHEREHW TVR
|
| Detection Method: | |
| Confidence: | 142.38764 |
| Match: | 1erjA_ |
| Description: | Tup1, C-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 6.67009948605948 | bayes_pls_golite062009 | |
| snoRNA binding | 4.78410616474982 | bayes_pls_golite062009 |
| RNA binding | 3.77273677738815 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.79445416141967 | bayes_pls_golite062009 |
| binding | 2.42570478946173 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
| transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
| dynein binding | 1.74989209255308 | bayes_pls_golite062009 |
| DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
| structural molecule activity | 1.31060431370834 | bayes_pls_golite062009 |
| protein binding | 1.21879977456466 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.19593750149343 | bayes_pls_golite062009 |
| transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
| mRNA binding | 1.05053985350578 | bayes_pls_golite062009 |
| histone binding | 0.685319917508843 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.625780732991652 | bayes_pls_golite062009 |
| actin binding | 0.529861581509437 | bayes_pls_golite062009 |
| transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
| DNA helicase activity | 0.220747580531792 | bayes_pls_golite062009 |
| chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
|
Region A: Residues: [131-535] |
1 11 21 31 41 51
| | | | | |
1 KRLVAHDNDI QDICWAPDSS ILVTVGLDRS VIVWNGSTFE KLKRFDVHQS LVKGVVFDPA 60
61 NKYFATTSDD RTMKIFRYHK TGDISFTIEH IITEPFKESP LTTYFRRPSW SPDGQHIAVP 120
121 NATNGPVSSM AIVNRGTWDT NVSLIGHDAP TEVARFNPRL FERNAGVKQK KDDDPENALV 180
181 GQNDDKVHHF DKNIDSVVAT AGQDKSLAVW STSRPRPILV AFDIANKSIT DMSWNPDGSL 240
241 LFVASLDSSI TLFKFENNEL GKPIPLEKNM EQLYRYGVDK DSLDFPESIN QLLLEDQTKS 300
301 FKHTKISTSK LGENHPTLAT NSASNQKDNN DASVSRSEHI NILIPKRKKD AILNKAVTLK 360
361 SGKKRVAPTL ISTSSSSPFS NGIKKPTLDS KRIENNVKSS TKTIN
|
| Detection Method: | |
| Confidence: | 2.221849 |
| Match: | 1k32A_ |
| Description: | Tricorn protease; Tricorn protease N-terminal domain; Tricorn protease domain 2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 6.67009948605948 | bayes_pls_golite062009 | |
| snoRNA binding | 4.78410616474982 | bayes_pls_golite062009 |
| RNA binding | 3.77273677738815 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.79445416141967 | bayes_pls_golite062009 |
| binding | 2.42570478946173 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
| transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
| dynein binding | 1.74989209255308 | bayes_pls_golite062009 |
| DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
| structural molecule activity | 1.31060431370834 | bayes_pls_golite062009 |
| protein binding | 1.21879977456466 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.19593750149343 | bayes_pls_golite062009 |
| transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
| mRNA binding | 1.05053985350578 | bayes_pls_golite062009 |
| histone binding | 0.685319917508843 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.625780732991652 | bayes_pls_golite062009 |
| actin binding | 0.529861581509437 | bayes_pls_golite062009 |
| transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
| DNA helicase activity | 0.220747580531792 | bayes_pls_golite062009 |
| chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
|
Region A: Residues: [536-607] |
1 11 21 31 41 51
| | | | | |
1 SKNTLLNVPE GVEKKISISS FPLPRLGIHS LIMGTKERSA WKISNSELEN DDADNAGGKG 60
61 SDGTSNSIDD IA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [608-840] |
1 11 21 31 41 51
| | | | | |
1 VLSEEENDFH RMTLNAKLTQ EKIWSEEPTT RCLLQSDVIP DTDVVVLEGG SLDDIAVLEI 60
61 RNGVERSIQF DSEALLDNPT RILGYQGGKR TIETFIPEVI ICAIGSKDCK CWCLASANGS 120
121 IYILSYNGQQ RIPKICLGHK VIKMVTSSKY LLVLTERGLF FAWDLLDLKL VLRNVPILPI 180
181 LNGQPIHGNK VRINKVIKCF RLDGSSCDLL LEVGDPKNVY KWTKDLGCWS LYK
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
