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View Structure Prediction Details

Protein: PDR3
Organism: Saccharomyces cerevisiae
Length: 976 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR3.

Description E-value Query
Range
Subject
Range
gi|7706833 - gi|7706833|gb|AAD13897.2|S58126_111111 Unknown [Saccharomyces cerevisiae]
0.0 [5..969] [36..1058]
gi|1706177 - sp|P52959|CT1B_FUSSO CUTINASE TRANSCRIPTION FACTOR 1 BETA
CTF1B_FUSSO - Cutinase transcription factor 1 beta OS=Fusarium solani subsp. pisi GN=CTF1-BETA PE=2 SV=1
2.0E-59 [296..517] [231..431]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-42 [417..579] [321..501]
SPAC3C7.04 - transcription factor
YF54_SCHPO - Uncharacterized transcriptional regulatory protein C3C7.04 OS=Schizosaccharomyces pombe (strain 972 ...
1.0E-42 [2..324] [27..386]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVKKSTRSK VSTACVNCRK RKIKCTGKYP CTNCISYDCT CVFLKKHLPQ KEDSSQSLPT  60
   61 TAVAPPSSHA NVEASADVQH LDTAIKLDNQ YYFKLMNDLI QTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.144602
Match: 1ajyA_
Description: PUT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
sequence-specific DNA binding 2.98081393153291 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 2.24483536326713 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [104-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSPSATHAPD TSNNPTNDNN ILFKDDSKYQ NQLVTYQNIL TNLYALPPCD DTQLLIDKTK  60
   61 SQLNNLINSW NPEINYPKLS SFSPRPQRSI ETYLLTNKYR NKIHMTRFSF WTDQMVKSQS 120
  121 PDSFLATTPL VDEVFGLFSP IQAFSLRGIG YLIKKNIENT GSSMLIDTKE TIYLILRLFD 180
  181 LCYEHLIQGC ISISNPLENY LQKIKQTPTT TASASLPTSP APLSNDLVIS VIHQLPQPFI 240
  241 QSITGFTTTQ LIENLHDSFS MFRIVTQMYA QHRKRFAEFL NQAFSLPHQE KSVLFSSFCS 300
  301 S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [405-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYLLSTLCYA YYNVTLYHML DINTLDYLEI LVSLLEIQNE IDERFGFEKM LEVAVTCSTK  60
   61 MGLSRWEYYV GIDENTAERR RKIWWKIYSL EKRFLTDLGD LSLINEHQMN CLLPKDFRDM 120
  121 GFINHKEFLT KIGT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.396 0.375 regulation of transcription from RNA polymerase II promoter a.74.1 Cyclin-like
View Download 0.571 0.047 transcription activator activity a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.330 0.006 DNA binding a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.315 0.001 transcription activator activity a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.313 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.304 N/A N/A d.110.4 SNARE-like
View Download 0.301 N/A N/A a.74.1 Cyclin-like
View Download 0.299 N/A N/A d.58.26 GHMP Kinase, C-terminal domain
View Download 0.267 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.266 N/A N/A c.116.1 alpha/beta knot
View Download 0.256 N/A N/A a.90.1 Transcription factor STAT-4 N-domain
View Download 0.243 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.241 N/A N/A a.26.1 4-helical cytokines
View Download 0.237 N/A N/A a.185.1 Gametocyte protein Pfg27
View Download 0.236 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.231 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.226 N/A N/A d.110.2 GAF domain-like
View Download 0.224 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.212 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.210 N/A N/A a.3.1 Cytochrome c
View Download 0.202 N/A N/A d.110.4 SNARE-like

Predicted Domain #4
Region A:
Residues: [539-976]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLSPSSPKL KNLSLSRLIE YGELAIAQIV GDFFSETLYN EKFTSLEVSV KPTIIRQKLL  60
   61 EKVFEDIESF RLKLAKIKLH TSRVFQVAHC KYPEYPKNDL IEAAKFVSYH KNTWFSILGA 120
  121 VNNLIARLSE DPEVITEQSM KYANEMFQEW REINQFLIQV DTDFIVWACL DFYELIFFVM 180
  181 ASKFYVEDPH ITLEDVINTL KVFKRITNII SFFNNNLDEK DYDCQTFREF SRSSSLVAIS 240
  241 IRIIFLKYCY AEQIDRAEFI ERLKEVEPGL SDLLREFFDT RSFIYRYMLK SVEKSGFHLI 300
  301 IRKMLESDYK FLYRDKLATG NIPDQGNSSQ ISQLYDSTAP SYNNASASAA NSPLKLSSLL 360
  361 NSGEESYTQD ASENVPCNLR HQDRSLQQTK RQHSAPSQIS ANENNIYNLG TLEEFVSSGD 420
  421 LTDLYHTLWN DNTSYPFL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.571 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.396 a.74.1 Cyclin-like
View Download 0.330 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.315 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.313 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain

Predicted Domain #5
Region A:
Residues: [525-754]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFINHKEFLT KIGTSSLSPS SPKLKNLSLS RLIEYGELAI AQIVGDFFSE TLYNEKFTSL  60
   61 EVSVKPTIIR QKLLEKVFED IESFRLKLAK IKLHTSRVFQ VAHCKYPEYP KNDLIEAAKF 120
  121 VSYHKNTWFS ILGAVNNLIA RLSEDPEVIT EQSMKYANEM FQEWREINQF LIQVDTDFIV 180
  181 WACLDFYELI FFVMASKFYV EDPHITLEDV INTLKVFKRI TNIISFFNNN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [755-976]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDEKDYDCQT FREFSRSSSL VAISIRIIFL KYCYAEQIDR AEFIERLKEV EPGLSDLLRE  60
   61 FFDTRSFIYR YMLKSVEKSG FHLIIRKMLE SDYKFLYRDK LATGNIPDQG NSSQISQLYD 120
  121 STAPSYNNAS ASAANSPLKL SSLLNSGEES YTQDASENVP CNLRHQDRSL QQTKRQHSAP 180
  181 SQISANENNI YNLGTLEEFV SSGDLTDLYH TLWNDNTSYP FL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle