YRC Public Data Repository - Protein Structure Prediction

Protein:	BPL1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	631 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BPL1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|28921970, gi\|... - gi\|32409781\|ref\|XP_325371.1\| hypothetical protein [Neurospora crassa], gi\|28921970\|gb\|EAA31242.1\| pr... gi\|85097606 - gi\|85097606\|ref\|XP_960478.1\| hypothetical protein NCU05516 [Neurospora crassa OR74A]	449.0	[0..1]	[630..12]
gi\|238880422 - gi\|238880422\|gb\|EEQ44060.1\| hypothetical protein CAWG_02319 [Candida albicans WO-1] orf19.7645 - orf19.7645 CGDID:CAL0000887 Assembly 19, Contig19-2518 (182803, 180806) CDS, reverse complemented, t... gi\|68473197, gi\|... - gi\|68473197\|ref\|XP_719404.1\| hypothetical protein CaO19.7645 [Candida albicans SC5314], gi\|46441220\|...	442.0	[0..1]	[630..1]
gi\|42549274, gi\|... - gi\|46127903\|ref\|XP_388505.1\| hypothetical protein FG08329.1 [Gibberella zeae PH-1], gi\|42549274\|gb\|E...	435.0	[0..1]	[631..6]
gi\|145018672, gi... - gi\|39974835\|ref\|XP_368808.1\| hypothetical protein MGG_00436 [Magnaporthe grisea 70-15], gb\|EAA48778....	432.0	[0..1]	[630..6]
gi\|169783670 - gi\|169783670\|ref\|XP_001826297.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83775041 - gi\|83775041\|dbj\|BAE65164.1\| unnamed protein product [Aspergillus oryzae]	429.0	[0..2]	[630..14]
gi\|115395862, gi... - gi\|115395862\|ref\|XP_001213570.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	426.0	[0..1]	[631..11]
gi\|67539770, gi\|... - gi\|67539770\|ref\|XP_663659.1\| hypothetical protein AN6055.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	425.0	[0..10]	[630..54]
BPL1 - Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for ace... BPL1_YEAST - Biotin--protein ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BPL1 PE=1 SV=1	420.0	[0..1]	[630..1]
gi\|49652591, gi\|... - gi\|50410019\|ref\|XP_456927.1\| hypothetical protein DEHA0A14168g [Debaryomyces hansenii CBS767], gi\|49...	408.0	[0..1]	[631..1]
gi\|71001216, gi\|... - gi\|71001216\|ref\|XP_755289.1\| biotin apo-protein ligase [Aspergillus fumigatus Af293], gi\|66852927\|gb...	399.0	[0..8]	[630..40]

Back

Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVLIYNGNG ASKICLLRTF QSLLPFVVPL YAMRFVDAST LEKEPWPAST ALLVMPGGRD  60
   61 MGYCSSFNET IYRKITDFVK RGGAYLGLCA GGYFGSAVVD FRMPDSDLNV VGKRKLQFFP 120
  121 GTCAGPTFPG FTYDSEDGAR RASIIVDGMQ SSPVHTHIYF NGGGSFLETE NYSNVKVVAR 180
  181 YQETDFEKSA AIIYVKVGKG NVVLTGIHPE FSAEGSPILD KRDEKTRLEL LSYILKLLGL 240
  241 KVPKDTSKCG QPTLTDQYLF P

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.30103
Match:	1t3tA
Description:	Structure of Formylglycinamide synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
nucleic acid binding	0.86323855032533	bayes_pls_golite062009
binding	0.588714599255874	bayes_pls_golite062009
anthranilate synthase activity	0.243205818526006	bayes_pls_golite062009
O-acyltransferase activity	0.161871631961278	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.125344146311784	bayes_pls_golite062009
kinase activity	0.0876337684295744	bayes_pls_golite062009
protein binding	0.0152024556625711	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [262-631]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNVETKRFIE KALTNKVKNQ DEDTLYTFQF SDISSEIPEH QLANLDISAD LSDSDNEIVK  60
   61 IWYGDEEKIC KKAKPSFDLE LYAKLINGCR FGLPIIVAPV IRSTQTLLDK NYRFLDSTNT 120
  121 GFTVLGNYQT AGRGRGQNMW VSPYGTLAFS FIINVDAKNF STTPIALFQY LMALAVVRGI 180
  181 REYAPGYENI PAFIKWPNDV YVRVDKGGIN FQGKQYMKLS GIIVTSNYRK NVLHLVVGCG 240
  241 INVSNLGPTV SLNTLVDEWN KNSDNPRLEK FSFEKLLASV LNQFDRYHRL LLEEGFSLIL 300
  301 PEYYQYWLHS NQTVNLASGG KAIIQGITSD FGFLLAQLLN ENNEPTTKVV HLQPDGNSFD 360
  361 LMRNLITRKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.69897
Match:	1biaA
Description:	THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	4.83057889638134	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	4.8294067084702	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	4.8294067084702	bayes_pls_golite062009
ligase activity	3.51191116674556	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
sequence-specific DNA binding	1.49235608772623	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	1.35137682451633	bayes_pls_golite062009
transcription activator activity	1.33116476470017	bayes_pls_golite062009
binding	0.904147650999471	bayes_pls_golite062009
threonine-tRNA ligase activity	0.793195358470619	bayes_pls_golite062009
glycine-tRNA ligase activity	0.788242088202643	bayes_pls_golite062009
serine-tRNA ligase activity	0.681379128250628	bayes_pls_golite062009
transcription regulator activity	0.63339258210663	bayes_pls_golite062009
nucleic acid binding	0.609853081467937	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.49179487858702	bayes_pls_golite062009
DNA binding	0.48413861319521	bayes_pls_golite062009
alanine-tRNA ligase activity	0.435766663027965	bayes_pls_golite062009
histidine-tRNA ligase activity	0.334773354741163	bayes_pls_golite062009
lysine-tRNA ligase activity	0.333541891861949	bayes_pls_golite062009
ATP binding	0.18403217430648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.145955341735342	bayes_pls_golite062009
adenyl nucleotide binding	0.127823774098159	bayes_pls_golite062009
structural molecule activity	0.00764692706195469	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: