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Protein Overview: BPL1_YEAST

General Information:
Name(s) found: BPL1_YEAST [Swiss-Prot]
Description(s) found:
  • Biotin--protein ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BPL1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 690 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVLVYNGPG TTPGSVKHAV ESLRDFLEPY YAVSTVNVKV LQTEPWMSKT SAVVFPGGAD  60
   61 LPYVQACQPI ISRLKHFVSK QGGVFIGFCA GGYFGTSRVE FAQGDPTMEV SGSRDLRFFP 120
  121 GTSRGPAYNG FQYNSEAGAR AVKLNLPDGS QFSTYFNGGA VFVDADKFDN VEILATYAEH 180
  181 PDVPSSDSGK GQSENPAAVV LCTVGRGKVL LTGPHPEFNV RFMRKSTDKH FLETVVENLK 240
  241 AQEIMRLKFM RTVLTKTGLN CNNDFNYVRA PNLTPLFMAS APNKRNYLQE MENNLAHHGM 300
  301 HANNVELCSE LNAETDSFQF YRGYRASYDA ASSSLLHKEP DEVPKTVIFP GVDEDIPPFQ 360
  361 YTPNFDMKEY FKYLNVQNTI GSLLLYGEVV TSTSTILNNN KSLLSSIPES TLLHVGTIQV 420
  421 SGRGRGGNTW INPKGVCAST AVVTMPLQSP VTNRNISVVF VQYLSMLAYC KAILSYAPGF 480
  481 SDIPVRIKWP NDLYALSPTY YKRKNLKLVN TGFEHTKLPL GDIEPAYLKI SGLLVNTHFI 540
  541 NNKYCLLLGC GINLTSDGPT TSLQTWIDIL NEERQQLHLD LLPAIKAEKL QALYMNNLEV 600
  601 ILKQFINYGA AEILPSYYEL WLHSNQIVTL PDHGNTQAMI TGITEDYGLL IAKELVSGSS 660
  661 TQFTGNVYNL QPDGNTFDIF KSLIAKKVQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..263] MSA 4.010916 View MSA. No confident structure predictions are available.
    2 View Details [264..348] deduced N/A No confident structure predictions are available.
    3 View Details [349..622] PSI-BLAST 85.68867 Biotin repressor, N-terminal domain; Biotin repressor/biotin holoenzyme synthetase, C-terminal domain; Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain
    4 View Details [623..690] PSI-BLAST 85.68867 Biotin repressor, N-terminal domain; Biotin repressor/biotin holoenzyme synthetase, C-terminal domain; Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • aminoacyl-tRNA ligase activity
    		•  4.83057889638134 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  4.8294067084702 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  4.8294067084702 bayes_pls_golite062009
  • ligase activity
    		•  3.75598318664255 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  1.35137682451633 bayes_pls_golite062009
  • binding
    		•  0.904147650999471 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  0.793195358470619 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  0.788242088202643 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  0.681379128250628 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.63339258210663 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.609853081467937 bayes_pls_golite062009
  • DNA binding
    		•  0.48413861319521 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  0.435766663027965 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  0.334773354741163 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  0.333541891861949 bayes_pls_golite062009
  • ATP binding
    		•  0.18403217430648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.145955341735342 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.127823774098159 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle