| Protein: | pan-PH |
| Organism: | Drosophila melanogaster |
| Length: | 747 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pan-PH.
| Description | E-value | Query Range |
Subject Range |
|
|
391.0 | [0..1] | [747..1] |
|
Region A: Residues: [1-192] |
1 11 21 31 41 51
| | | | | |
1 MPHTHSRHGS SGDDLCSTDE VKIFKDEGDR EDEKISSENL LVEEKSSLID LTESEEKGHK 60
61 ISRPDHSPVF NKLDTHAPSF NMGYLVSPYS YANGSPSGLP VTMANKIGLP PFFCHNADPL 120
121 STPPPAHCGI PPYQLDPKMG LTRPALYPFA GGQYPYPMLS SDMSQVASWH TPSVYSASSF 180
181 RTPYPSSLPI NT
|
| Detection Method: |  |
| Confidence: | 76.130768 |
| Match: | PF08347.2 |
| Description: | No description for PF08347.2 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [193-259] |
1 11 21 31 41 51
| | | | | |
1 TLASDFPFRF SPSLLPSVHA TSHHVINAHS AIVGVSSKQE CGVQDPTTNN RYPRNLEAKH 60
61 TSNAQSN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [260-372] |
1 11 21 31 41 51
| | | | | |
1 ESKETTNDKK KPHIKKPLNA FMLYMKEMRA KVVAECTLKE SAAINQILGR RWHALGREEQ 60
61 AKYYELARRE RQLHMQMYPD WSSRTNASRG KKRKRKQDTN DGGNNMKKCR ARF
|
| Detection Method: | |
| Confidence: | 13.522879 |
| Match: | 2lefA |
| Description: | Lymphoid enhancer-binding factor, LEF1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA binding | 5.15324651287773 | bayes_pls_golite062009 |
| nucleic acid binding | 5.01228762819617 | bayes_pls_golite062009 |
| transcription regulator activity | 4.9607192917135 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.06355503548774 | bayes_pls_golite062009 |
| transcription factor activity | 3.82658263870186 | bayes_pls_golite062009 |
| binding | 3.6211482127468 | bayes_pls_golite062009 |
| transcription repressor activity | 3.17018042329608 | bayes_pls_golite062009 |
| transcription activator activity | 2.95665802871704 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.75319687398598 | bayes_pls_golite062009 |
| protein binding | 2.18211240370246 | bayes_pls_golite062009 |
| beta-catenin binding | 2.16058631208641 | bayes_pls_golite062009 |
| chromatin binding | 1.64428658020027 | bayes_pls_golite062009 |
| transcription factor binding | 1.10315330167937 | bayes_pls_golite062009 |
| DNA bending activity | 0.87985209274756 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.4255419067266 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.261169200304829 | bayes_pls_golite062009 |
|
Region A: Residues: [373-540] |
1 11 21 31 41 51
| | | | | |
1 GLDQQSQWCK PCRRKKKCIR YMEALNGNGP AEDGSCFDEH GSQLSDDDED DYDDDKLGGS 60
61 CGSADETNKI EDEDSESLNQ SMPSPGCLSG LSSLQSPSTT MSLASPLNMN ANSATNVIFP 120
121 ASSNALLIVG ADQPTAQQRP TLVSTSGSSS GSTSSISTTP NTSSTVSP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [541-747] |
1 11 21 31 41 51
| | | | | |
1 VTCMTGPCLG SSQERAMMLG NRFSHLGMGL SPPVVSTSTS KSEPFFKPHP TVCNNPIFAL 60
61 PSIGNCSLNI SSMPNTSRNP IGANPRDINN PLSINQLTKR REYKNVELIE ASESKTIVAH 120
121 AATSIIQHVA VNGYHANHSL LNSNLGHLHH QLNNRTENPN RSEQTMLSVS NHSVNSSECH 180
181 KESDSQAIVS SNPPNAGSSD NGVISVS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
