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View Structure Prediction Details

Protein: gi|123993257, gi...
Organism: synthetic construct
Length: 207 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123993257, gi....

Description E-value Query
Range
Subject
Range
gi|60653441 - gi|60653441|gb|AAX29415.1| nuclear transcription factor Y beta [synthetic construct]
3.0E-69 [1..207] [1..207]
gi|73977777 - gi|73977777|ref|XP_532675.2| PREDICTED: similar to nuclear transcription factor-Y beta isoform 1 [Ca...
2.0E-68 [1..207] [1..207]
NFYB_BOVIN - Nuclear transcription factor Y subunit beta OS=Bos taurus GN=NFYB PE=2 SV=1
3.0E-68 [1..207] [1..207]
gi|13937859 - gi|13937859|gb|AAH07035.1| Nuclear transcription factor Y, beta [Homo sapiens]
4.0E-68 [1..207] [1..207]
gi|579588|emb|CA... - unnamed protein product [Homo sapiens]
NFYB_RAT - Nuclear transcription factor Y subunit beta OS=Rattus norvegicus GN=Nfyb PE=1 SV=1
NFYB_MOUSE - Nuclear transcription factor Y subunit beta OS=Mus musculus GN=Nfyb PE=1 SV=1
4.0E-68 [1..207] [1..207]
NFYB_HORSE - Nuclear transcription factor Y subunit beta OS=Equus caballus GN=NFYB PE=2 SV=1
6.0E-68 [1..207] [1..207]
NFYB_CHICK - Nuclear transcription factor Y subunit beta OS=Gallus gallus GN=NFYB PE=2 SV=2
7.0E-68 [3..207] [1..205]
gi|105492, gi|35050 - gi|35050|emb|CAA42230.1| CAAT-box DNA binding protein subunit B (NF-YB) [Homo sapiens], gi|105492|pi...
gi|109098520, gi... - gi|109098520|ref|XP_001097495.1| PREDICTED: similar to Nuclear transcription factor Y subunit beta (...
8.0E-68 [3..207] [1..205]
gi|38156576, gi|... - gi|38156576|gb|AAR12910.1| nuclear transcription factor-Y B subunit 3 [Bufo gargarizans], gi|3815657...
6.0E-67 [3..207] [1..206]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLP  60
   61 IANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILF 120
  121 AMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVTATDG LSEELTEEAF TNQLPAGLIT 180
  181 TDGQQQNVMV YTTSYQQISG VQQIQFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1n1jA
Description: Nuclear transcription factor Y subunit beta (Nf-Yb3)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 4.04353148658823 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
transcription activator activity 2.58408368884371 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
protein binding 2.1291876005999 bayes_pls_golite062009
sequence-specific DNA binding 1.18653213156155 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription repressor activity 0.72554769377984 bayes_pls_golite062009
transcription initiation factor activity 0.0945459819298291 bayes_pls_golite062009
transcription corepressor activity 0.0736756545988504 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle