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View Structure Prediction Details

Protein: ULP2_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ULP2_SCHPO.

Description E-value Query
Range
Subject
Range
SENP7_MOUSE - Sentrin-specific protease 7 OS=Mus musculus GN=Senp7 PE=1 SV=1
317.0 [0..98] [622..494]
gi|109494222, gi... - gi|109494222|ref|XP_001057745.1| PREDICTED: similar to SUMO1/sentrin specific protease 7 isoform 2 [...
313.0 [0..97] [622..466]
gi|74002566 - gi|74002566|ref|XP_545077.2| PREDICTED: similar to Sentrin-specific protease 7 (Sentrin/SUMO-specifi...
296.0 [0..54] [622..458]
gi|12697959 - gi|12697959|dbj|BAB21798.1| KIAA1707 protein [Homo sapiens]
295.0 [0..97] [622..210]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPWMINQGHS LVFFPRLENK GLTLPRLLIH IPILIFLQSR GTSPNDAIPI KSPLERLANS  60
   61 VTSPEKPTVR TAIQKDSPRR KQIDDDQTPP KHLKRSFQNV TVVSPRKKKT IDVVELPFTK 120
  121 GGYGGFYDPR PGCLKFTTHE INVSYTDTSI PVIHIPVQLL KRCCWLQGWR DNLVESPVHA 180
  181 IHLTLKNRDM KRITIGDSAS LLFLYNPLHV ESARAGLDLL DQSDFSLTSP SSAKEFKQLL 240
  241 TLKQSTIIPR TPQKTVRSIV KQTSSPH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [268-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKMPKHSLP SSPTPFNSNS GDSLLSRIKN SNQSSSERPT ANNGAQEQNQ SSSSAGNTSN  60
   61 DFSTLCSQGS DKTLLSDASC TTILVYPFSG TNSIAITNTD LTRLNEGEFL NDTIVDFYLR 120
  121 YLYCKLQTQN PSLANDTHIF NTFFYNRLTS KDKDGKRLGH RGVRKWTQKV DLFHKKYIIV 180
  181 PINETFHWYL AIICNIDRLM PVDTKLEEQD EIVMSSVEQP SASKTRQAEL TSNSPAILIF 240
  241 DSLANLHKGA LNYLREYLLE EAFERKNVHL KSTDIRGFHA KVPQQSNFSD CGIYALHFVE 300
  301 LFLETPEQVI ANTLDKSLRR TDAKNFDQQW NLQKINTMRC DLKGLIRRLS TEWSSNNERQ 360
  361 SLSSGSNDEE DKENDDDLAI LPITN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.30103
Match: 1tgzA
Description: Structure of human Senp2 in complex with SUMO-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine-type peptidase activity 6.54685807643041 bayes_pls_golite062009
small conjugating protein-specific protease activity 6.39247995905454 bayes_pls_golite062009
ubiquitin-specific protease activity 5.52987342617304 bayes_pls_golite062009
SUMO-specific protease activity 4.63546214004196 bayes_pls_golite062009
ubiquitin thiolesterase activity 3.91170685383331 bayes_pls_golite062009
thiolester hydrolase activity 2.1617608442198 bayes_pls_golite062009
binding 1.77258741259391 bayes_pls_golite062009
peptidase activity 1.2363147273892 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.10408384086394 bayes_pls_golite062009
protein binding 1.08139200376412 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
hydrolase activity 0.785819892845781 bayes_pls_golite062009
NEDD8-specific protease activity 0.687958315289315 bayes_pls_golite062009
nucleic acid binding 0.439226369799415 bayes_pls_golite062009
endopeptidase activity 0.366512660710683 bayes_pls_golite062009
cysteine-type endopeptidase activity 0.352657819388643 bayes_pls_golite062009
DNA binding 0.168761518285256 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.144331158319621 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle