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View Structure Prediction Details

Protein: gi|58176764, gi|...
Organism: Homo sapiens
Length: 278 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|58176764, gi|....

Description E-value Query
Range
Subject
Range
gi|8117799 - gi|8117799|gb|AAF72776.1|AF168395_1 MHC class I antigen [Pan troglodytes]
337.0 [0..2] [278..21]
gi|15808083 - gi|15808083|gb|AAK67484.1| MHC class I antigen [Pongo pygmaeus]
335.0 [0..2] [278..21]

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Predicted Domain #1
Region A:
Residues: [1-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM  60
   61 EDWKQDSQLQ KAREDIFMET LKDIVEYYKD STGSHVLQGR FGCEIENNRS SGAFWKYYYD 120
  121 GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI 180
  181 LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG 240
  241 TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1t7vA
Description: Zn-alpha-2-glycoprotein; baculo-ZAG PEG 200
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptide antigen binding 11.0753660234769 bayes_pls_golite062009
olfactory receptor activity 10.396146040408 bayes_pls_golite062009
endogenous lipid antigen binding 5.5147652266332 bayes_pls_golite062009
antigen binding 4.70353060278319 bayes_pls_golite062009
lipid antigen binding 4.56479935637638 bayes_pls_golite062009
transmembrane receptor activity 4.47335611545936 bayes_pls_golite062009
receptor activity 4.41760011727341 bayes_pls_golite062009
exogenous lipid antigen binding 3.9281017962636 bayes_pls_golite062009
G-protein coupled receptor activity 3.81042605880111 bayes_pls_golite062009
molecular transducer activity 3.44808015198907 bayes_pls_golite062009
signal transducer activity 3.44808015198907 bayes_pls_golite062009
natural killer cell lectin-like receptor binding 2.87337850935774 bayes_pls_golite062009
MHC class I receptor activity 2.8317290648207 bayes_pls_golite062009
fibroblast growth factor 1 binding 2.64517375056633 bayes_pls_golite062009
IgG binding 2.59905791929203 bayes_pls_golite062009
peptide binding 2.55584703989799 bayes_pls_golite062009
protein binding 2.20481087437436 bayes_pls_golite062009
binding 2.11682283742138 bayes_pls_golite062009
receptor binding 2.03767222253534 bayes_pls_golite062009
immunoglobulin receptor activity 2.03064643363242 bayes_pls_golite062009
fibroblast growth factor binding 1.78492923920341 bayes_pls_golite062009
growth factor binding 1.60826091835429 bayes_pls_golite062009
IgG receptor activity 1.15013317153047 bayes_pls_golite062009
nucleic acid binding 1.04968338629714 bayes_pls_golite062009
transcription regulator activity 0.970538938724296 bayes_pls_golite062009
DNA binding 0.927264427044344 bayes_pls_golite062009
IgE binding 0.92099524949571 bayes_pls_golite062009
IgE receptor activity 0.92099524949571 bayes_pls_golite062009
hydrolase activity 0.82153990973861 bayes_pls_golite062009
coreceptor activity 0.661209696849389 bayes_pls_golite062009
cell adhesion molecule binding 0.63737386998612 bayes_pls_golite062009
cytokine binding 0.631436442105379 bayes_pls_golite062009
integrin binding 0.599569390248921 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.447829399094714 bayes_pls_golite062009
cytokine receptor activity 0.34165331857492 bayes_pls_golite062009
transcription activator activity 0.325578910694349 bayes_pls_golite062009
transcription factor activity 0.292011507820264 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.28309679787333 bayes_pls_golite062009
MHC class II receptor activity 0.251167772391909 bayes_pls_golite062009
catalytic activity 0.115804452291889 bayes_pls_golite062009

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