YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56553689, gi\|...
Organism:	Mus musculus
Length:	105 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56553689, gi|....

Description	E-value	Query Range	Subject Range
gi\|47221757 - gi\|47221757\|emb\|CAG08811.1\| unnamed protein product [Tetraodon nigroviridis]	151.0	[0..1]	[105..33]
PHS2_MOUSE - Pterin-4-alpha-carbinolamine dehydratase 2 OS=Mus musculus GN=Pcbd2 PE=1 SV=2	147.0	[0..1]	[105..32]
CE18240 - WBGene00020397 locus:pcbd-1 status:Partially_confirmed	147.0	[0..8]	[103..82]
gi\|157745959 - gi\|157745959\|ref\|XP_001668076.1\| Hypothetical protein CBG03930 [Caenorhabditis briggsae AF16] gi\|39595301, gi\|... - gi\|39595301\|emb\|CAE60338.1\| Hypothetical protein CBG03930 [Caenorhabditis briggsae], gi\|187036132\|em...	145.0	[0..8]	[103..49]
gi\|157132864, gi... - gi\|157132864\|ref\|XP_001662676.1\| hypothetical protein AaeL_AAEL002898 [Aedes aegypti], gi\|108881639\|...	144.0	[0..9]	[103..125]
gi\|73971304 - gi\|73971304\|ref\|XP_852425.1\| PREDICTED: similar to dimerization cofactor of hepatocyte nuclear facto...	143.0	[0..4]	[105..43]
gi\|52354802, gi\|... - gi\|52354802\|gb\|AAH82836.1\| LOC397951 protein [Xenopus laevis], gi\|147898540\|ref\|NP_001081611.1\| XDCo...	143.0	[0..3]	[105..1]
gi\|57033048, gi\|... - gi\|57033048\|gb\|AAH88970.1\| LOC496367 protein [Xenopus laevis], gi\|148237203\|ref\|NP_001088985.1\| hypo... gi\|52139103, gi\|... - gi\|89271979\|emb\|CAJ82265.1\| 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte...	142.0	[0..3]	[105..1]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSMSSDAQWL TAEERDQLIP GLKAAGWSEL SERDAIYKEF SFKNFNQAFG FMSRVALQAE  60
   61 KMNHHPEWFN VYNKVQITLT SHDCGGLTKR DVKLAQFIEK AAASL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1ru0A
Description:	Crystal structure of DCoH2, a paralog of DCoH, the Dimerization Cofactor of HNF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	6.27157822952381	bayes_pls_golite062009
transcription regulator activity	2.43253022834875	bayes_pls_golite062009
phenylalanine 4-monooxygenase activity	2.07153680701772	bayes_pls_golite062009
binding	1.91757396487631	bayes_pls_golite062009
transcription activator activity	1.76965686339133	bayes_pls_golite062009
protein binding	1.5922433129317	bayes_pls_golite062009
catalytic activity	1.39967796334655	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	1.1107181321593	bayes_pls_golite062009
carbon-oxygen lyase activity	0.738746392707103	bayes_pls_golite062009
hydro-lyase activity	0.699903508958642	bayes_pls_golite062009
lyase activity	0.685050647082958	bayes_pls_golite062009
transcription factor binding	0.303837517417996	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: