| Protein: | FBpp0305533 |
| Organism: | Drosophila melanogaster |
| Length: | 1518 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305533.
| Description | E-value | Query Range |
Subject Range |
|
|
391.0 | [0..1011] | [1508..38] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MTLSRGPYSE LDKMSLFQDL KLKRRKIDSR CSSDGESIAD TSTSSPDLLA PMSPKLCDSG 60
61 SAGASLGASL PLPLALPLPM ALPLPMSLPL PLTAASSAVT VSLAAVVAAV AETGGAGAGG 120
121 AGTAVTASGA GPCV
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [135-353] |
1 11 21 31 41 51
| | | | | |
1 STSSTTAAAA TSSTSSLSSS SSSSSSTSSS TSSASPTAGA SSTATCPASS SSSSGNGSGG 60
61 KSGSIKQEHT EIHSSSSAIS AAAASTVMSP PPAEATRSSP ATPEGGGPAG DGSGATGGGN 120
121 TSGGSTAGVA INEHQNNGNG SGGSSRASPD SLEEKPSTTT TTGRPTLTPT NGVLSSASAG 180
181 TGISTGSSAK LSEAGMSVIR SVKEERLLNV SSKMLVFHQ
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [354-648] |
1 11 21 31 41 51
| | | | | |
1 QREQETKAVA AAAAAAAAGH VTVLVTPSRI KSEPPPPASP SSTSSTQRER ERERDRERDR 60
61 ERERERDRDR EREREQSISS SQQHLSRVSA SPPTQLSHGS LGPNIVQTHH LHQQLTQPLT 120
121 LRKSSPPTEH LLSQSMQHLT QQQAIHLHHL LGQQQQQQQA SHPQQQQQQQ HSPHSLVRVK 180
181 KEPNVGQRHL SPHHQQQSPL LQHHQQQQQQ QQQQQQHLHQ QQQQQQHHQQ QPQALALMHP 240
241 ASLALRNSNR DAAILFRVKS EVHQQVAAGL PHLMQSAGGA AAAAAAAVAA QRMVC
|
| Detection Method: | |
| Confidence: | 2.06 |
| Match: | 2i1jA |
| Description: | No description for 2i1jA was found. |
|
Region A: Residues: [649-897] |
1 11 21 31 41 51
| | | | | |
1 FSNARINGVK PEVIGGPLGN LRPVGVGGGN GSGSVQCPSP HPSSSSSSSQ LSPQTPSQTP 60
61 PRGTPTVIMG ESCGVRTMVW GYEPPPPSAG QSHGQHPQQQ QQSPHHQPQQ QQQQQQQQSQ 120
121 QQQQQQQQQS LGQQQHCLSS PSAGSLTPSS SSGGGSVSGG GVGGPLTPSS VAPQNNEEAA 180
181 QLLLSLGQTR IQDMRSRPHP FRTPHALNME RLWAGDYSQL PPGQLQALNL SAQQQQWGSS 240
241 NSTGLGGVG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [898-1060] |
1 11 21 31 41 51
| | | | | |
1 GGMGGRNLEA PHEPTDEDEQ PLVCMICEDK ATGLHYGIIT CEGCKGFFKR TVQNRRVYTC 60
61 VADGTCEITK AQRNRCQYCR FKKCIEQGMV LQAVREDRMP GGRNSGAVYN LYKVKYKKHK 120
121 KTNQKQQQQA AQQQQQQAAA QQQHQQQQQH QQHQQHQQQQ LHS
|
| Detection Method: | |
| Confidence: | 29.0 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1061-1194] |
1 11 21 31 41 51
| | | | | |
1 PLHHHHHQGH QSHHAQQQHH PQLSPHHLLS PQQQQLAAAV AAAAQHQQQQ QQQQQQQQQA 60
61 KLMGGVVDMK PMFLGPALKP ELLQAPPMHS PAQQQQQQQQ QQQQQQASPH LSLSSPHQQQ 120
121 QQQQGQHQNH HQQQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1195-1518] |
1 11 21 31 41 51
| | | | | |
1 GGGGGGAGGG AQLPPHLVNG TILKTALTNP SEIVHLRHRL DSAVSSSKDR QISYEHALGM 60
61 IQTLIDCDAM EDIATLPHFS EFLEDKSEIS EKLCNIGDSI VHKLVSWTKK LPFYLEIPVE 120
121 IHTKLLTDKW HEILILTTAA YQALHGKRRG EGGGSRHGSP ASTPLSTPTG TPLSTPIPSP 180
181 AQPLHKDDPE FVSEVNSHLS TLQTCLTTLM GQPIAMEQLK LDVGHMVDKM TQITIMFRRI 240
241 KLKMEEYVCL KVYILLNKEV ELESIQERYV QVLRSYLQNS SPQNPQARLS ELLSHIPEIQ 300
301 AAASLLLESK MFYVPFVLNS ASIR
|
| Detection Method: | |
| Confidence: | 67.0 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription repressor activity | 2.20686235000733 | bayes_pls_golite062009 |
| receptor activity | 2.07573173722434 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.28118886948947 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| molecular transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| signal transducer activity | 1.19872119297817 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.99801784942981 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
