| Protein: | nhr-23 |
| Organism: | Caenorhabditis elegans |
| Length: | 437 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-23.
| Description | E-value | Query Range |
Subject Range |
|
|
275.0 | [0..5] | [434..57] |
|
Region A: Residues: [1-119] |
1 11 21 31 41 51
| | | | | |
1 MRVSAQIEVI PCKVCGDKSS GVHYGVITCE GCKGFFRRSQ SSIVNYQCPR QKNCVVDRVN 60
61 RNRCQYCRLK KCIELGMSRD AVKFGRMSKK QREKVEDEVR MHKELAANGL GYQAIYGDY
|
| Detection Method: |  |
| Confidence: | 21.39794 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [120-437] |
1 11 21 31 41 51
| | | | | |
1 SPPPSHPSYC FDQSMYGHYP SGTSTPVNGY SIAVAATPTT PMPQNMYGAT PSSTNGTQYV 60
61 AHQATGGSFP SPQVPEEDVA TRVIRAFNQQ HSSYTTQHGV CNVDPDCIPH LSRAGGWELF 120
121 ARELNPLIQA IIEFAKSIDG FMNLPQETQI QLLKGSVFEL SLVFAAMYYN VDAQAVCGER 180
181 YSVPFACLIA EDDAEMQLIV EVNNTLQEIV HLQPHQSELA LLAAGLILEQ VSSSHGIGIL 240
241 DTATIATAET LKNALYQSVM PRIGCMEDTI HRIQDVETRI RQTARLHQEA LQNFRMSDPT 300
301 SSEKLPALYK ELFTADRP
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 2.42118322312622 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
