| Protein: | nhr-168 |
| Organism: | Caenorhabditis elegans |
| Length: | 448 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-168.
| Description | E-value | Query Range |
Subject Range |
|
|
261.0 | [0..2] | [447..20] |
|
Region A: Residues: [1-143] |
1 11 21 31 41 51
| | | | | |
1 MEPPGCSKVS SVDSIDFDFP ELPSIIQKEP NRTARSESPA RQRHQRPSEC SICGKTANGY 60
61 HYDVPSCNGC KTFFRRLCVS EKSFICKAGG DCFNLTKRKV PLKCRACRYE KCISEGMNPN 120
121 AMLLDEKEAT AENFKKLKKR VNQ
|
| Detection Method: |  |
| Confidence: | 23.522879 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [144-448] |
1 11 21 31 41 51
| | | | | |
1 SNPKDPDDDS GEDIEHQIEK KQVIKDVACI ENKMQKLVDM LNYLERKVTK FRMSAYNPHW 60
61 STLPGLEAFL LLENKISLAD RSGPMPGWPL KTQSSPPKIP EFGKKPTGPA YSPDQKCWIL 120
121 YDLMVSIEYA KTFMFFHQLD SRDRLVLMRY VALALMNLHI SYFTVAKKYD TIIHPDGKLA 180
181 PMKKGMVYAE TVMSIAPLIR CEIQETEFVL LKAICLCNPA VPDLSQHAQE ILGREREQYA 240
241 DALFDHCLRN RKDGPSQFAE LIGMVDLLER QQRMQKDLHL LHVAPFVSKI PQKDKMLLVD 300
301 DIMNF
|
| Detection Method: | |
| Confidence: | 25.522879 |
| Match: | 1ilgA |
| Description: | Pregnane x receptor, PXR |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone binding | 0.895172563790297 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| hormone receptor binding | 0.74373733735458 | bayes_pls_golite062009 |
| steroid binding | 0.687964316511791 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| bile acid binding | 0.209530484888186 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| lipid binding | 0.100602722157819 | bayes_pls_golite062009 |
