| Protein: | nhr-129 |
| Organism: | Caenorhabditis elegans |
| Length: | 420 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-129.
| Description | E-value | Query Range |
Subject Range |
|
|
288.0 | [0..2] | [420..75] |
|
Region A: Residues: [1-144] |
1 11 21 31 41 51
| | | | | |
1 MDEPSCSNSP VDLPEIIPQL KVYAERPKDC FVCGGSASGY HYDVPACNGC KTFFRRYVIS 60
61 KRLFTCKLND DCFDLSTRDV PVKCRACRIN KCFAVGMNPH ALEVDKTNTD CLKEVTKRKN 120
121 MIGNDAVNEK QLVLNSLESM ENKI
|
| Detection Method: |  |
| Confidence: | 23.221849 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [145-420] |
1 11 21 31 41 51
| | | | | |
1 QKIADMLTYL ELKLDQFRAS SYNPHWAEVR GLEFVLNSTN RISLADKFGP MPGWPLLDNN 60
61 LSPSRPPPLS HEKLVIGGPP PYSPKKKHWL YFNMLATIEY AKTFMFFHEL LPRDQLILIR 120
121 YTTLACVNLL VSFSSVSKKY DTAVHPDGTL QMHRNQEYYS SNVMSIIPLI RYQVQQIEYV 180
181 LLKAICLCNP AVPDLSKHAQ LLLAEERQKY SEALLDHCIR NIGNGPSRFT DLIGIIDVLE 240
241 RQQRMQKDLH LLYIAPLVAK TPKDNIVQII EDVMDS
|
| Detection Method: | |
| Confidence: | 30.0 |
| Match: | 1xzxX |
| Description: | Thyroxine-Thyroid Hormone Receptor Interactions |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 4.66615836207965 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator activity | 3.20381581407476 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.01488410150634 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| promoter binding | 1.16363620574097 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| juvenile hormone binding | 0.814202236506491 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| estrogen response element binding | 4.73336420190096E-4 | bayes_pls_golite062009 |
