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View Structure Prediction Details

Protein: TBA3_RAT
Organism: Rattus norvegicus
Length: 450 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TBA3_RAT.

Description E-value Query
Range		 Subject
Range
gi|73996516 - gi|73996516|ref|XP_850665.1| PREDICTED: similar to Tubulin alpha-2 chain (Alpha-tubulin 2) isoform 2...
 0.0 [1..450] [1..449]
gi|115960583, gi... - gi|72057626|ref|XP_780117.1| PREDICTED: similar to tubulin, alpha 2 isoform 1 [Strongylocentrotus pu...
 0.0 [1..450] [1..450]
TBA1C_MOUSE - Tubulin alpha-1C chain OS=Mus musculus GN=Tuba1c PE=1 SV=1
gi|124481732, gi... - gi|148225011|ref|NP_001091315.1| hypothetical protein LOC100037141 [Xenopus laevis], gi|124481732|gb...
TBA1C_CRIGR - Tubulin alpha-1C chain OS=Cricetulus griseus GN=TUBA1C PE=2 SV=1
 0.0 [1..450] [1..449]
gi|47229230 - gi|47229230|emb|CAG03982.1| unnamed protein product [Tetraodon nigroviridis]
 0.0 [2..450] [553..1029]
TBA_XENLA - (P08537) Tubulin alpha chain
 0.0 [1..450] [1..449]
gi|60653689 - gi|60653689|gb|AAX29538.1| tubulin alpha 6 [synthetic construct]
 0.0 [1..450] [1..449]
gi|91076358 - gi|91076358|ref|XP_966407.1| PREDICTED: similar to alpha-tubulin isoform 1 [Tribolium castaneum]
 0.0 [1..450] [1..450]
gi|114644941 - gi|114644941|ref|XP_001158840.1| PREDICTED: tubulin alpha 6 isoform 1 [Pan troglodytes]
gi|123990474, gi... - gi|123999316|gb|ABM87234.1| tubulin, alpha 6 [synthetic construct], gi|123990474|gb|ABM83912.1| tubu...
TUBA1C - tubulin, alpha 1c
 0.0 [1..450] [1..449]

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Predicted Domain #1
Region A:
Residues: [1-450] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK  60
   61 HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDLVLD 120
  121 RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YGKKSKLEFA IYPAPQVSTA 180
  181 VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA 240
  241 SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN 300
  301 QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP 360
  361 TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
  421 AREDLAALEK DYEEVGVDSV EAEAEEGEEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1z2bA
Description: Tubulin-colchicine-vinblastine: stathmin-like domain complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of cytoskeleton 4.04224160177678 bayes_pls_golite062009
structural molecule activity 3.32779015200848 bayes_pls_golite062009
tubulin binding 2.4432045213385 bayes_pls_golite062009
cytoskeletal protein binding 2.24606230377981 bayes_pls_golite062009
binding 2.00508289492248 bayes_pls_golite062009
GTPase activity 1.87512665946067 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.77500173070686 bayes_pls_golite062009
pyrophosphatase activity 1.7017047947554 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.68267378160702 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.68038087466376 bayes_pls_golite062009
protein binding 1.60795853516357 bayes_pls_golite062009
MHC class I protein binding 1.46574865275013 bayes_pls_golite062009
gamma-tubulin binding 1.02742779831447 bayes_pls_golite062009
hydrolase activity 0.502038132260603 bayes_pls_golite062009
receptor binding 0.00945891657658993 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle