YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|124804794, gi...
Organism:	Plasmodium falciparum 3D7
Length:	171 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124804794, gi....

Description	E-value	Query Range	Subject Range
gi\|70951400 - gi\|70951400\|ref\|XP_744943.1\| translation initiation factor eIF-1A [Plasmodium chabaudi chabaudi] gi\|56525100 - gi\|56525100\|emb\|CAH79051.1\| translation initiation factor eIF-1A, putative [Plasmodium chabaudi chab...	180.0	[0..6]	[156..1]
gi\|68062752 - gi\|68062752\|ref\|XP_673385.1\| translation initiation factor [Plasmodium berghei strain ANKA] gi\|56491199 - gi\|56491199\|emb\|CAH94512.1\| translation initiation factor eIF-1A, putative [Plasmodium berghei]	180.0	[0..6]	[157..1]
eIF-1A-PA, eIF-1... - The gene Eukaryotic initiation factor 1A is referred to in FlyBase by the symbol Dmel\eIF-1A (CG8053... gi\|195449988, gi... - gi\|195449988\|ref\|XP_002072314.1\| GK22392 [Drosophila willistoni], gi\|194168399\|gb\|EDW83300.1\| GK2239... gi\|195569935, gi... - gi\|195569935\|ref\|XP_002102964.1\| GD19223 [Drosophila simulans], gi\|194198891\|gb\|EDX12467.1\| GD19223 ... gi\|220948970, gi... - gi\|220957690\|gb\|ACL91388.1\| eIF-1A-PA [synthetic construct], gi\|220948970\|gb\|ACL87028.1\| eIF-1A-PA [... gi\|194764537, gi... - gi\|194764537\|ref\|XP_001964385.1\| GF23078 [Drosophila ananassae], gi\|190614657\|gb\|EDV30181.1\| GF23078... gi\|190651367, gi... - gi\|194900238\|ref\|XP_001979664.1\| GG22826 [Drosophila erecta], gi\|190651367\|gb\|EDV48622.1\| GG22826 [D... gi\|38047995, gi\|... - gi\|38047995\|gb\|AAR09900.1\| similar to Drosophila melanogaster eIF-1A [Drosophila yakuba], gi\|1954975... gi\|193899766, gi... - gi\|195062888\|ref\|XP_001996271.1\| GH22399 [Drosophila grimshawi], gi\|193899766\|gb\|EDV98632.1\| GH22399... gi\|54639054, gi\|... - gi\|54639054\|gb\|EAL28456.1\| GA20792 [Drosophila pseudoobscura pseudoobscura], gi\|125776545\|ref\|XP_001... gi\|195109642, gi... - gi\|195109642\|ref\|XP_001999392.1\| GI24484 [Drosophila mojavensis], gi\|193915986\|gb\|EDW14853.1\| GI2448... gi\|125776545\|ref... - GA20792-PA [Drosophila pseudoobscura], GA20792 [Drosophila pseudoobscura pseudoobscura] gi\|194112158, gi... - gi\|195152353\|ref\|XP_002017101.1\| GL21704 [Drosophila persimilis], gi\|194112158\|gb\|EDW34201.1\| GL2170... gi\|194122588, gi... - gi\|195348897\|ref\|XP_002040983.1\| GM15296 [Drosophila sechellia], gi\|194122588\|gb\|EDW44631.1\| GM15296... gi\|194152697, gi... - gi\|195391928\|ref\|XP_002054611.1\| GJ24550 [Drosophila virilis], gi\|194152697\|gb\|EDW68131.1\| GJ24550 [...	179.0	[0..1]	[146..1]
gi\|83320111, gi\|... - gi\|83320111\|ref\|NP_001020500.1\| eukaryotic translation initiation factor 1A, X-linked [Bos taurus], ...	179.0	[0..1]	[131..1]
gi\|51766992, gi\|... - gi\|94394220\|ref\|XP_977854.1\| PREDICTED: similar to X-linked eukaryotic translation initiation factor...	179.0	[0..1]	[131..1]
gi\|30584999, gi\|... - gi\|61371489\|gb\|AAX43676.1\| eukaryotic translation initiation factor 1A X-linked [synthetic construct...	179.0	[0..1]	[131..1]
gi\|91079674 - gi\|91079674\|ref\|XP_967161.1\| PREDICTED: similar to Eukaryotic initiation factor 1A CG8053-PA [Tribol...	178.0	[0..1]	[146..1]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKNKGKGGK NRRRGKNDNE GEKRELLYKE EDQEYAQVLR MLGNGRLEAH CFDGVKRLCH  60
   61 IRGKMRKRVW INSGDIILVS LRDYQDSKAD VIAKYTPDEA RSLKAHGELP ETAKINETDI 120
  121 FDDDGQNGVE FLDDESDEEA QEEMNNARRL DIEDVNIKQE NLYKKICVTY L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.154902
Match:	1d7qA
Description:	Translation initiation factor-1a, eIF1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	6.60650180781768	bayes_pls_golite062009
structural molecule activity	6.0174879876147	bayes_pls_golite062009
translation initiation factor activity	5.09596850944863	bayes_pls_golite062009
nucleic acid binding	3.27576062206528	bayes_pls_golite062009
binding	2.83465364476231	bayes_pls_golite062009
DNA binding	2.56243510083541	bayes_pls_golite062009
RNA binding	1.76502371106766	bayes_pls_golite062009
translation regulator activity	1.46320772716954	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.40718318783582	bayes_pls_golite062009
structure-specific DNA binding	1.0106133269798	bayes_pls_golite062009
transcription regulator activity	0.756094573447167	bayes_pls_golite062009
single-stranded DNA binding	0.72848534873424	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	0.474251377131502	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	0.47336621289748	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	0.47336621289748	bayes_pls_golite062009
sequence-specific DNA binding	0.21650406007586	bayes_pls_golite062009
protein binding	0.152645195799531	bayes_pls_golite062009
transcription factor activity	0.0591886273075271	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: