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Protein Overview: eIF-1A-PA, eIF-1...

General Information:
Name(s) found: FBpp0310418 [FlyBase]
eIF-1A-PB / FBpp0089421 [FlyBase]
eIF-1A-PA / FBpp0082994 [FlyBase]
Description(s) found:
Found 39 descriptions.
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  • type=protein; loc=3R:join(14100660..14100863,14107416..14107658); ID=FBpp0310418; name=eIF-1A-PC; parent=FBgn0026250,FBtr0343927; dbxref=FlyBase:FBpp0310418,FlyBase_Annotation_IDs:CG8053-PC; MD5=1f1f22606b5bbf48d900d7a3071d2f4d; length=148; release=r5.56; species=Dmel; [FlyBase]
  • The gene Eukaryotic initiation factor 1A is referred to in FlyBase by the symbol Dmel\eIF-1A (CG8053, FBgn0026250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14100387..14108206. It has the cytological map location 91A1. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; mitotic spindle elongation; mitotic spindle organization; phagocytosis, engulfment. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Eukaryotic initiation factor 1A is referred to in FlyBase by the symbol Dmel\eIF-1A (CG8053, FBgn0026250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14100387..14108206. It has the cytological map location 91A1. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; mitotic spindle elongation; mitotic spindle organization; phagocytosis, engulfment. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic 43S preinitiation complex [ISS]
    cytosol [ISS][NAS]
    Biological Process: mitotic spindle elongation [IMP]
    phagocytosis, engulfment [IMP]
    mitotic spindle organization [IMP]
    smoothened signaling pathway [IGI]
    translational initiation [IEA][ISS][NAS]
    translation [ISS]
    Molecular Function: translation initiation factor activity [ISS]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKNKGKGGK NRRRGKNENE FEKRELIFKE DQQEYAQVTK MLGNGRLEAM CFDGVKRLCH  60
   61 IRGKLRKKVW INQGDIILVG LRDYQDSKAD VILKYTPDEA RNLKTYGEFP ESVRINETVT 120
  121 FVEDGFDEDI EFGDEISSED DADSVDNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 42.39794 Translation initiation factor-1a, eIF1a


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle