YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264526, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	881 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264526, gi|....

Description	E-value	Query Range	Subject Range
SYV_BACCR - Valine--tRNA ligase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9... gi\|228723162, gi... - gi\|229048175\|ref\|ZP_04193744.1\| Valyl-tRNA synthetase [Bacillus cereus AH676], gi\|228723162\|gb\|EEL74... gi\|229111929, gi... - gi\|229111929\|ref\|ZP_04241473.1\| Valyl-tRNA synthetase [Bacillus cereus Rock1-15], gi\|228671493\|gb\|EE...	0.0	[1..881]	[1..881]
SYV_BACHK - Valine--tRNA ligase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=valS PE=3 SV=1 SYV_BACHK - Valyl-tRNA synthetase OS=Bacillus thuringiensis subsp. konkukian GN=valS PE=3 SV=1	0.0	[1..881]	[1..881]
gi\|89200302, gi\|... - gi\|89200302\|ref\|ZP_01179056.1\| Valyl-tRNA synthetase, class Ia [Bacillus cereus subsp. cytotoxis NVH...	0.0	[1..881]	[1..881]
SYV_BACC1 - Valine--tRNA ligase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=valS PE=3 SV=1	0.0	[1..881]	[1..881]
SYV_BACCZ - Valine--tRNA ligase OS=Bacillus cereus (strain ZK / E33L) GN=valS PE=3 SV=1	0.0	[1..881]	[1..881]
gi\|75759956, gi\|... - gi\|75759956\|ref\|ZP_00740025.1\| Valyl-tRNA synthetase [Bacillus thuringiensis serovar israelensis ATC... gi\|218541207, gi... - gi\|218899626\|ref\|YP_002448037.1\| valyl-tRNA synthetase [Bacillus cereus G9842], gi\|218541207\|gb\|ACK9...	0.0	[1..881]	[1..881]
gi\|47566648, gi\|... - gi\|47566648\|ref\|ZP_00237470.1\| valyl-tRNA synthetase [Bacillus cereus G9241], gi\|47556678\|gb\|EAL1501... gi\|228625395, gi... - gi\|229158076\|ref\|ZP_04286146.1\| Valyl-tRNA synthetase [Bacillus cereus ATCC 4342], gi\|228625395\|gb\|E...	0.0	[1..881]	[1..881]
SYV_GEOKA - Valyl-tRNA synthetase OS=Geobacillus kaustophilus GN=valS PE=3 SV=1 SYV_GEOKA - Valine--tRNA ligase OS=Geobacillus kaustophilus (strain HTA426) GN=valS PE=3 SV=1	0.0	[1..881]	[1..880]
gi\|89156742, gi\|... - gi\|89205258\|ref\|ZP_01183829.1\| Valyl-tRNA synthetase, class Ia [Bacillus weihenstephanensis KBAB4], ...	0.0	[1..881]	[1..881]
SYV_GEOSE - Valine--tRNA ligase OS=Geobacillus stearothermophilus GN=valS PE=1 SV=1	0.0	[1..881]	[1..880]

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Predicted Domain #1

Region A:
Residues: [1-881]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTEKNLPT KYDHMSVEEG LYQWWLEGKY FEATGDEKKQ PYTIVIPPPN VTGKLHLGHA  60
   61 WDTTLQDILT RTKRMQGYDV LWLPGMDHAG IATQAKVEGK LREEGISRYD LGREKFLEKA 120
  121 WEWKEEYASH IRQQWGKVGL GLDYSRERFT LDKGLSDAVN KVFVQLYEKG LIYRGEYIIN 180
  181 WDPATRTALS DIEVIHKEVQ GAFYHMNYPL TDGSGHIRLA TTRPETMLGD TAVAVHPEDD 240
  241 RYKHLIGKTV TLPIVGREIP IIADEYVEKD FGTGVVKITP AHDPNDFEVG NRHDLPRILV 300
  301 MNEDGSMNEK AGKYNGMDRF ECRKALVKDL QEAGVLVEIE PHMHSVGHSE RSGAVVEPYL 360
  361 STQWFVKMAP LAEKAIELQQ KEEEKVTFVP DRFENTYLRW MENIHDWCIS RQLWWGHRIP 420
  421 AWYHKETGEV YVGTEAPADI ENWNQDNDVL DTWFSSALWP FSTLGWPNED AADFKRYYST 480
  481 DALVTGYDII FFWVSRMIFQ GLEFTGERPF KDVLIHGLVR DEQGRKMSKS LGNGIDPMDV 540
  541 IEKYGADAMR FFLSTGSAPG QDLRFSMEKV ESTWNFINKI WNASRFVLMN MDDMKYEEID 600
  601 LTGEKSVADK WILTRLNETI ESVTRNMDKY EFGEAGRSLY NFIWDDFCDW YIEMAKLPLY 660
  661 GEDEAAKKTT RSILAYVLDQ TMRLLHPFMP FVTEKIWQHL PHEGESITVA AWPTVREDLQ 720
  721 DTEAAAEMHL LVDIIRSVRN IRAEVNTPMS KKVQMQIKAK DEAVLAQLTK NSSYIERFCN 780
  781 PSELTIQTDL QAPEKAMTAI VTGAELFLPL ADLINLDEER ARLEKELEKF DKEVERVQKK 840
  841 LSNQGFVAKA PAAVIEGERA KEQDYLEKRE AVRQRLADLE K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1gaxA
Description:	Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
isoleucine-tRNA ligase activity	8.08916111251946	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.22739538544605	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.22739538544605	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.21678612388154	bayes_pls_golite062009
leucine-tRNA ligase activity	7.03538514482698	bayes_pls_golite062009
ligase activity	5.98606099120849	bayes_pls_golite062009
valine-tRNA ligase activity	3.82183938334805	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.51931993626103	bayes_pls_golite062009
catalytic activity	1.41356903593784	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
binding	1.13704377394657	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
protein binding	0.241603585422086	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009
mRNA binding	2.82524485163416E-5	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: