YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263917, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	638 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263917, gi|....

Description	E-value	Query Range	Subject Range
gi\|228625944, gi... - gi\|229157494\|ref\|ZP_04285571.1\| Stage V sporulation protein D [Bacillus cereus ATCC 4342], gi\|228625... gi\|47565787, gi\|... - gi\|47565787\|ref\|ZP_00236826.1\| penicillin-binding protein 1, putative [Bacillus cereus G9241], gi\|47... gi\|228987060, gi... - gi\|228987060\|ref\|ZP_04147185.1\| Stage V sporulation protein D [Bacillus thuringiensis serovar tochig...	0.0	[1..638]	[1..638]
gi\|49330446, gi\|... - gi\|49478890\|ref\|YP_037977.1\| sporulation specific penicillin-binding protein [Bacillus thuringiensis...	0.0	[1..638]	[1..638]
gi\|51975042, gi\|... - gi\|52141573\|ref\|YP_085256.1\| sporulation specific penicillin-binding protein [Bacillus cereus E33L],...	0.0	[1..638]	[1..638]
gi\|42738936, gi\|... - gi\|42783009\|ref\|NP_980256.1\| sporulation specific penicillin-binding protein [Bacillus cereus ATCC 1...	0.0	[1..638]	[1..638]
gi\|29897560, gi\|... - gi\|30022004\|ref\|NP_833635.1\| stage V sporulation protein D / sporulation specific D,D-transpeptidase... gi\|228631462, gi... - gi\|229152113\|ref\|ZP_04280308.1\| Stage V sporulation protein D [Bacillus cereus m1550], gi\|228631462\|... gi\|229146487, gi... - gi\|229146487\|ref\|ZP_04274858.1\| Stage V sporulation protein D [Bacillus cereus BDRD-ST24], gi\|228637... gi\|218159239, gi... - gi\|218231282\|ref\|YP_002368715.1\| sporulation specific penicillin-binding protein [Bacillus cereus B4... gi\|228922668, gi... - gi\|228922668\|ref\|ZP_04085968.1\| Stage V sporulation protein D [Bacillus thuringiensis serovar huazho... gi\|228654430, gi... - gi\|229129193\|ref\|ZP_04258166.1\| Stage V sporulation protein D [Bacillus cereus BDRD-Cer4], gi\|228654... gi\|229111385, gi... - gi\|229111385\|ref\|ZP_04240938.1\| Stage V sporulation protein D [Bacillus cereus Rock1-15], gi\|2286721... gi\|228723847, gi... - gi\|229047600\|ref\|ZP_04193190.1\| Stage V sporulation protein D [Bacillus cereus AH676], gi\|228723847\|... gi\|228799649, gi... - gi\|228960133\|ref\|ZP_04121797.1\| Stage V sporulation protein D [Bacillus thuringiensis serovar pakist...	0.0	[1..638]	[1..638]
gi\|229061521, gi... - gi\|229061521\|ref\|ZP_04198865.1\| Stage V sporulation protein D [Bacillus cereus AH603], gi\|228717755\|... gi\|228748354, gi... - gi\|229013100\|ref\|ZP_04170265.1\| Stage V sporulation protein D [Bacillus mycoides DSM 2048], gi\|22874... gi\|228614812, gi... - gi\|229168656\|ref\|ZP_04296378.1\| Stage V sporulation protein D [Bacillus cereus AH621], gi\|228614812\|... gi\|89152928, gi\|... - gi\|89209138\|ref\|ZP_01187595.1\| Stage V sporulation protein D [Bacillus weihenstephanensis KBAB4], gi...	0.0	[1..638]	[1..638]
gi\|25297735 - pir\|\|D83971 stage V sporulation protein (soprulation specific penicillin-binding protein) (spore cor... gi\|15615135, gi\|... - gi\|15615135\|ref\|NP_243438.1\| stage V sporulation protein (soprulation specific penicillin-binding pr...	0.0	[1..638]	[1..638]
gi\|89148868, gi\|... - gi\|89203111\|ref\|ZP_01181808.1\| Stage V sporulation protein D [Bacillus cereus subsp. cytotoxis NVH 3...	0.0	[1..638]	[1..638]
gi\|56379491, gi\|... - gi\|56419649\|ref\|YP_146967.1\| penicillin-binding protein (sporulation specific penicillin-binding pro...	0.0	[1..636]	[1..635]
gi\|52785493, gi\|... - gi\|52785493\|ref\|YP_091322.1\| SpoVD [Bacillus licheniformis ATCC 14580], gi\|52347995\|gb\|AAU40629.1\| S...	0.0	[1..638]	[1..638]

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Predicted Domain #1

Region A:
Residues: [1-638]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVSNVTVRK RLIFILISGI LIFTIIDIRL GYVQFFLGNM LTDRAKDSWS RNITFEPERG  60
   61 KILDRNGVEL ATNKSAPTVF VVPRQIEKPA ETAEKLAAVL GVEKDEIYKR ITKKESIVRL 120
  121 DKGGRKISHD KAKEVRGLSL KGVYIAEDSI RYYPFGNFLS HVLGFAGSDN QGLMGLEKYY 180
  181 DKELNGDEGH VRFFADAKGQ RMPNVGDDFK KPEAGLNLGL TIDARINRIM EREMNIAEST 240
  241 YNPDGMIAIA MNPKNGEILG MSSRPSFDPA DFQSVSPEVY NRNLPVWSTY EPGSTFKIIT 300
  301 LAAALNENLV DLEKDTFYDD GAAEVGGARL KCWKAGGHGS QTFLEVVQNS CNPGFIELGD 360
  361 RLGKERLFKY IRNFGFGQKT GIDLQGEGSG ILFNLDKVGP VEQATTSFGQ GVSVTPIQQV 420
  421 AAVAAAVNGG TLYQPYIAKE FIDPKNNQVV SKKTPVDKRK VISKETSEKV RYALENVVAK 480
  481 GSGKGAFIDG YRVGGKTGTA QKVKDGKYLE NNYIVSFIGF APADDPEIVV YVAVDNPKGV 540
  541 TQFGGVVAAP IVGNILRDAL PVMGVKPRKE QVEREYKWGD IPTVEVPNLI GMKKKDLQTQ 600
  601 LVDLKLDISG DGEKVIKQSP EAGAKVKEGS KIRIYFGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1rp5A
Description:	PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
drug binding	3.43867028493374	bayes_pls_golite062009
serine-type D-Ala-D-Ala carboxypeptidase activity	3.12650314537616	bayes_pls_golite062009
penicillin binding	2.89507018520983	bayes_pls_golite062009
serine-type carboxypeptidase activity	2.70174066798582	bayes_pls_golite062009
serine-type exopeptidase activity	2.69091897402517	bayes_pls_golite062009
carboxypeptidase activity	1.96547160092829	bayes_pls_golite062009
hydrolase activity	1.90776959475284	bayes_pls_golite062009
catalytic activity	1.85492008367309	bayes_pls_golite062009
peptidase activity	1.51270018803999	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.27480861613963	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.13698125224034	bayes_pls_golite062009
binding	1.11566650386305	bayes_pls_golite062009
serine hydrolase activity	0.402878339821269	bayes_pls_golite062009
serine-type peptidase activity	0.392678049813626	bayes_pls_golite062009
exopeptidase activity	0.150639262435765	bayes_pls_golite062009
protein binding	0.0666688846338231	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: