YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258541, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	921 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258541, gi|....

Description	E-value	Query Range	Subject Range
gi\|196038708, gi... - gi\|196038708\|ref\|ZP_03106016.1\| isoleucyl-tRNA synthetase [Bacillus cereus NVH0597-99], gi\|196030431... SYI1_BACHK - Isoleucine--tRNA ligase 1 OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=ileS1 PE=3 SV... SYI1_BACHK - Isoleucyl-tRNA synthetase 1 OS=Bacillus thuringiensis subsp. konkukian GN=ileS1 PE=3 SV=1	0.0	[1..921]	[1..921]
SYI1_BACC1 - Isoleucine--tRNA ligase 1 OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=ileS1 PE=3 SV=1	0.0	[1..921]	[1..921]
SYI1_BACCR - Isoleucine--tRNA ligase 1 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / N... gi\|228779324, gi... - gi\|228980504\|ref\|ZP_04140814.1\| Isoleucyl-tRNA synthetase [Bacillus thuringiensis Bt407], gi\|2287793... gi\|228723827, gi... - gi\|229047580\|ref\|ZP_04193170.1\| Isoleucyl-tRNA synthetase [Bacillus cereus AH676], gi\|228723827\|gb\|E... gi\|228940984, gi... - gi\|228940984\|ref\|ZP_04103542.1\| Isoleucyl-tRNA synthetase [Bacillus thuringiensis serovar berliner A... gi\|228973915, gi... - gi\|228973915\|ref\|ZP_04134490.1\| Isoleucyl-tRNA synthetase [Bacillus thuringiensis serovar thuringien... gi\|228637100, gi... - gi\|229146467\|ref\|ZP_04274838.1\| Isoleucyl-tRNA synthetase [Bacillus cereus BDRD-ST24], gi\|228637100\|... gi\|228631442, gi... - gi\|229152093\|ref\|ZP_04280288.1\| Isoleucyl-tRNA synthetase [Bacillus cereus m1550], gi\|228631442\|gb\|E... gi\|228672141, gi... - gi\|229111365\|ref\|ZP_04240918.1\| Isoleucyl-tRNA synthetase [Bacillus cereus Rock1-15], gi\|228672141\|g... gi\|228654410, gi... - gi\|229129173\|ref\|ZP_04258146.1\| Isoleucyl-tRNA synthetase [Bacillus cereus BDRD-Cer4], gi\|228654410\|... gi\|206971359, gi... - gi\|206971359\|ref\|ZP_03232310.1\| isoleucyl-tRNA synthetase [Bacillus cereus AH1134], gi\|206734131\|gb\|... SYI_BACC4 - Isoleucine--tRNA ligase OS=Bacillus cereus (strain B4264) GN=ileS PE=3 SV=1	0.0	[1..921]	[1..921]
SYI_GEOKA - Isoleucine--tRNA ligase OS=Geobacillus kaustophilus (strain HTA426) GN=ileS PE=3 SV=1 SYI_GEOKA - Isoleucyl-tRNA synthetase OS=Geobacillus kaustophilus GN=ileS PE=3 SV=1	0.0	[1..919]	[1..922]
SYI1_BACCZ - Isoleucine--tRNA ligase 1 OS=Bacillus cereus (strain ZK / E33L) GN=ileS1 PE=3 SV=1	0.0	[1..921]	[1..921]
gi\|47553019, gi\|... - gi\|47570310\|ref\|ZP_00240957.1\| isoleucyl-tRNA synthetase [Bacillus cereus G9241], gi\|47553019\|gb\|EAL...	0.0	[1..921]	[1..921]
SYI_BACCN - Isoleucine--tRNA ligase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98...	0.0	[1..921]	[1..921]
gi\|89208465, gi\|... - gi\|89208465\|ref\|ZP_01186970.1\| Isoleucyl-tRNA synthetase, class Ia [Bacillus weihenstephanensis KBAB...	0.0	[7..921]	[1..915]
SYI_MOOTA - Isoleucine--tRNA ligase OS=Moorella thermoacetica (strain ATCC 39073) GN=ileS PE=3 SV=1	0.0	[1..920]	[1..928]
gi\|89098730, gi\|... - gi\|89098730\|ref\|ZP_01171612.1\| isoleucyl-tRNA synthetase [Bacillus sp. NRRL B-14911], gi\|89086692\|gb...	0.0	[1..919]	[1..919]

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Predicted Domain #1

Region A:
Residues: [1-921]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYKNTLLMP KTEFPMRGNL PKREPAMQEK WAEMNIYETV QEHTKGRPLF VLHDGPPYAN  60
   61 GDIHMGHALN KVLKDFIVRY KSMTGFCAPY VPGWDTHGLP IEQALTNKGV KRKEMTVAEF 120
  121 RKLCAEYAYE QVERQREQFK RLGVRADWDN PYITLEPAYE AQQIKVFGDM AKKGYIYKGQ 180
  181 KPVYWSPTSE SALAEAEIEY QDKKSASIYV AFSVKDGKNV LEGDEKYIIW TTTPWTLPAN 240
  241 LGISVHPELE YAIVKVNDEK YIIASELFET VAKTLEWENA EVVKTVKGSE LEYTVAKHPF 300
  301 YDRDSLVMLG DHVTTDAGTG CVHTAPGHGE DDFIVGKKYG LEVLCPVDDK GVLTEEAPGF 360
  361 EGLFYDKANK PITEKLEEVG ALLKLTFITH SYPHDWRTKK PIIFRATAQW FASIEAFRKE 420
  421 LLEAVAETKW VPAWGETRLH NMVRDRGDWC ISRQRAWGVP IPVFYAENGD PIITDETINH 480
  481 VADLFREHGS NVWFEREAKD LLPEGFTHPG SPNGEFRKET DIMDVWFDSG SSHQAVLEER 540
  541 DDLQRPADLY LEGSDQYRGW FNSSLSTAVA VTGKAPYKGV LSHGFVLDGE GRKMSKSIGN 600
  601 IVVPKKIMDQ LGGDILRLWV SSVDYQSDVR ISDDILKQVA EVYRKIRNTF RFLLGNLDDF 660
  661 KPSENTVAVA ELREVDRYML VKLNDLITKV KEAYETYDFA AVYHAIHNFC TIDLSSFYLD 720
  721 FAKDILYIEG ANHEDRRAIQ TVLYDVLVAL TKLVTPILPH TADEVWPYIP GVTEESVQLT 780
  781 DMPEAVQLDD AEALKTKWDA FMTLRDDVLK ALEVARNEKV IGKSLNASIT LYPTAEMKAM 840
  841 LESINEDLKQ LFIVSEYKLG GMMEEAPADA PKYEHTAVVV AQATGETCER CWVVSETIGK 900
  901 DAEHETLCER CATVVKENYV K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ffyA
Description:	Isoleucyl-tRNA synthetase (IleRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
valine-tRNA ligase activity	7.13767629265822	bayes_pls_golite062009
leucine-tRNA ligase activity	7.03538514482698	bayes_pls_golite062009
isoleucine-tRNA ligase activity	6.38633897147986	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
binding	0.485102284225571	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: