YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263342, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	317 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263342, gi|....

Description	E-value	Query Range	Subject Range
gi\|22776498, gi\|... - gi\|23098273\|ref\|NP_691739.1\| zinc-binding oxidoreductase [Oceanobacillus iheyensis HTE831], gi\|22776...	4.0E-79	[1..314]	[1..309]
gi\|51975627, gi\|... - gi\|52142158\|ref\|YP_084672.1\| bifunctional protein: zinc-containing alcohol dehydrogenase; quinone ox...	5.0E-78	[1..317]	[1..317]
gi\|30021481, gi\|... - gi\|30021481\|ref\|NP_833112.1\| quinone oxidoreductase [Bacillus cereus ATCC 14579], gi\|29897036\|gb\|AAP...	6.0E-78	[1..317]	[1..317]
gi\|47564631, gi\|... - gi\|47564631\|ref\|ZP_00235676.1\| oxidoreductase, zinc-binding [Bacillus cereus G9241], gi\|47558783\|gb\|...	8.0E-77	[1..315]	[1..331]
gi\|86134306, gi\|... - gi\|86134306\|ref\|ZP_01052888.1\| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi\|85821169\|gb\|...	1.0E-76	[1..315]	[12..335]
gi\|163862688, gi... - gi\|89209002\|ref\|ZP_01187473.1\| Zinc-containing alcohol dehydrogenase superfamily [Bacillus weihenste... gi\|229167436, gi... - gi\|229167436\|ref\|ZP_04295174.1\| Alcohol dehydrogenase zinc-binding domain protein [Bacillus cereus A...	2.0E-76	[1..315]	[1..307]
gi\|75812768, gi\|... - gi\|75812768\|ref\|YP_320385.1\| zinc-containing alcohol dehydrogenase superfamily protein [Anabaena var...	3.0E-76	[1..314]	[321..635]
gi\|133733408, gi... - gi\|254935619\|ref\|ZP_05267316.1\| hypothetical protein LmonF6_00750 [Listeria monocytogenes F6900], gi... gi\|224498692 - gi\|224498692\|ref\|ZP_03667041.1\| hypothetical protein LmonF1_02921 [Listeria monocytogenes Finland 19... gi\|224502087 - gi\|224502087\|ref\|ZP_03670394.1\| hypothetical protein LmonFR_06142 [Listeria monocytogenes FSL R2-561... gi\|255025535 - gi\|255025535\|ref\|ZP_05297521.1\| hypothetical protein LmonocytFSL_02908 [Listeria monocytogenes FSL J... gi\|16802655 - gi\|16802655\|ref\|NP_464140.1\| hypothetical protein lmo0613 [Listeria monocytogenes EGD-e] gi\|25282948, gi\|... - pir\|\|AE1151 oxidoreductase homolog lmo0613 [imported] - Listeria monocytogenes (strain EGD-e), gi\|16... gi\|47096276, gi\|... - gi\|47096276\|ref\|ZP_00233873.1\| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/... gi\|254900154, gi... - gi\|254900154\|ref\|ZP_05260078.1\| hypothetical protein LmonJ_10085 [Listeria monocytogenes J0161], gi\|... gi\|127766320, gi... - gi\|254911292\|ref\|ZP_05261304.1\| hypothetical protein LmonJ2_00750 [Listeria monocytogenes J2818], gi... gi\|153173488, gi... - gi\|254828320\|ref\|ZP_05233007.1\| hypothetical protein LmonocytogeFSL_07662 [Listeria monocytogenes FS...	4.0E-76	[1..313]	[1..309]
gi\|229601380, gi... - gi\|229601380\|ref\|YP_002867708.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthrac... gi\|254738549 - gi\|254738549\|ref\|ZP_05196252.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|254752867 - gi\|254752867\|ref\|ZP_05204903.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|254759139 - gi\|254759139\|ref\|ZP_05211165.1\| oxidoreductase, zinc-binding dehydrogenase family protein [Bacillus ... gi\|21401433, gi\|... - gi\|65320790\|ref\|ZP_00393749.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|49186311, gi\|... - gi\|49186311\|ref\|YP_029563.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Sterne]... gi\|47503998, gi\|... - gi\|47528850\|ref\|YP_020199.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. 'Ames A... gi\|30263461, gi\|... - gi\|30263461\|ref\|NP_845838.1\| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Ames], ... gi\|165872349, gi... - gi\|165872349\|ref\|ZP_02216985.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|170708548, gi... - gi\|170708548\|ref\|ZP_02898989.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|167514952, gi... - gi\|167637445\|ref\|ZP_02395725.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|190564341, gi... - gi\|190565024\|ref\|ZP_03017945.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|172080588, gi... - gi\|177654623\|ref\|ZP_02936447.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthraci... gi\|227813662, gi... - gi\|227813662\|ref\|YP_002813671.1\| oxidoreductase, zinc-binding dehydrogenase family [Bacillus anthrac...	5.0E-76	[1..315]	[1..331]
gi\|110622401, gi... - gi\|147919259\|ref\|YP_687005.1\| NADPH:quinone reductase [uncultured methanogenic archaeon RC-I], gi\|11...	1.0E-75	[1..314]	[1..307]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAIGLTQYG DKSVLQEIEM QTPLLGDNDV LIEVYAAGVN PVDWKIREGL LQDVISYDFP  60
   61 LVLGWDVAGV VAAIGKNVTV FKVGDEVYSR PDIERNGTYA EYVAVDEKYV AKKPRNLSFE 120
  121 EAASIPLVGL TSWQSLVKFA NVQKGNKVLI HAGSGGIGTF AIQLAKSFGA HVATTTSTKN 180
  181 MQFVKDLGAD TVVDYKTEDF SLLLHNYNIV FDVLGGDVLK DSYKVLAPNG KLASIYGPKG 240
  241 MEIPQTEISR EKNIESDHIF TEPNGYELSL ITELIEGGKI KPVVTHVLPL HVEGVKKAHH 300
  301 ISESERARGK IVLKKHW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.69897
Match:	1rjwA
Description:	CRYSTAL STRUCTURE OF NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS STRAIN LLD-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
L-iditol 2-dehydrogenase activity	5.34392733627563	bayes_pls_golite062009
binding	2.72453765142308	bayes_pls_golite062009
protein binding	2.40625250158019	bayes_pls_golite062009
oxidoreductase activity	2.38343643417648	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.12541893067778	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	1.9802813264034	bayes_pls_golite062009
DNA binding	1.61355789916908	bayes_pls_golite062009
transcription regulator activity	1.55390653047158	bayes_pls_golite062009
nucleic acid binding	1.48478425318425	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.44179293407232	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.34145234546943	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.22416351603098	bayes_pls_golite062009
chaperone binding	1.19079350615542	bayes_pls_golite062009
retinol dehydrogenase activity	1.04497968922284	bayes_pls_golite062009
receptor binding	0.9771005334092	bayes_pls_golite062009
transcription factor activity	0.91090893050278	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.905392379451071	bayes_pls_golite062009
hydrolase activity	0.887975662837757	bayes_pls_golite062009
RNA binding	0.843556706364142	bayes_pls_golite062009
transporter activity	0.793769336118517	bayes_pls_golite062009
structural molecule activity	0.75267483298133	bayes_pls_golite062009
ligase activity	0.742884668104576	bayes_pls_golite062009
transmembrane transporter activity	0.635891484075352	bayes_pls_golite062009
substrate-specific transporter activity	0.555188550031886	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.51503848775098	bayes_pls_golite062009
molecular transducer activity	0.435382281024944	bayes_pls_golite062009
signal transducer activity	0.435382281024944	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.410307505174239	bayes_pls_golite062009
L-arabinitol 2-dehydrogenase activity	0.382131941157781	bayes_pls_golite062009
coenzyme binding	0.35922330382799	bayes_pls_golite062009
ion transmembrane transporter activity	0.29802814097478	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.261132005311306	bayes_pls_golite062009
active transmembrane transporter activity	0.239024094835991	bayes_pls_golite062009
receptor activity	0.219998435023684	bayes_pls_golite062009
catalytic activity	0.217171374336363	bayes_pls_golite062009
cation transmembrane transporter activity	0.212092278332619	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.178823255212317	bayes_pls_golite062009
G-protein coupled receptor activity	0.135469305070471	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.113340150368917	bayes_pls_golite062009
pyrophosphatase activity	0.0696058100530442	bayes_pls_golite062009
NAD or NADH binding	0.0664389065992004	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0591634687578807	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0560606007580392	bayes_pls_golite062009
transmembrane receptor activity	0.0180992866169776	bayes_pls_golite062009
gated channel activity	0.015794644474568	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: