YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30257265, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	712 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257265, gi|....

Description	E-value	Query Range	Subject Range
gi\|49329368, gi\|... - gi\|49477812\|ref\|YP_036757.1\| penicillin-binding protein transpeptidase domain-containing protein [Ba...	0.0	[1..712]	[1..712]
gi\|47553726, gi\|... - gi\|47569611\|ref\|ZP_00240288.1\| penicillin-binding protein 1 [Bacillus cereus G9241], gi\|47553726\|gb\|...	0.0	[1..712]	[1..712]
gi\|30020787, gi\|... - gi\|30020787\|ref\|NP_832418.1\| division specific D,D-transpeptidase / cell division protein ftsI [Baci... gi\|229128002, gi... - gi\|229128002\|ref\|ZP_04256985.1\| Peptidoglycan glycosyltransferase [Bacillus cereus BDRD-Cer4], gi\|22...	0.0	[1..712]	[1..712]
gi\|52142849, gi\|... - gi\|52142849\|ref\|YP_083981.1\| penicillin-binding protein transpeptidase domain-containing protein [Ba...	0.0	[1..712]	[1..712]
gi\|42781738, gi\|... - gi\|42781738\|ref\|NP_978985.1\| penicillin-binding protein [Bacillus cereus ATCC 10987], gi\|42737661\|gb...	0.0	[1..712]	[1..712]
gi\|65319954, gi\|... - gi\|65319954\|ref\|ZP_00392913.1\| COG0768: Cell division protein FtsI/penicillin-binding protein 2 [Bac...	0.0	[1..712]	[1..712]
gi\|163940437, gi... - gi\|89209089\|ref\|ZP_01187552.1\| Peptidoglycan glycosyltransferase [Bacillus weihenstephanensis KBAB4]...	0.0	[1..712]	[1..712]

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Predicted Domain #1

Region A:
Residues: [1-712]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKLQTNKGA RYFMIAFIVL FLIMLLRFFY IQAVGVVHNV NVKDLATEQH NKNGILEANR  60
   61 GTIYDQAGKV LVQDSTTYRV VVNLKGNGKL KNKDETAAQL ADALEINKED VLKNFHEGRT 120
  121 QVEIGKVGRN LTREKKEQIR KLKIPGVSFM PEKARVYPNE DFASYILGFA RPDDKGNTEG 180
  181 KFGLEKSLDK YLRSTNGNIE YVGGRGGIPL TNDIGKIEPA KHGNNVYLTL DKQINSFLEE 240
  241 AMNKAQDHYD PSMLLGIIAD PKTGKVLAMS SKPSFNPNKG DIEYFLNDPI ANAYEPGSTM 300
  301 KVFTLAAAIN EGVYNGKEYF QSGKYAVGSS DIKDHNGGFG WGSITFDEGF ERSSNVAFSI 360
  361 LEDQLLKPNK FKQYMNKFGF NQKTGIDLPG ESKNTLLLNT QIQQVTTSFG QGSTVTPIQL 420
  421 IQAATAIAND GKMMQPYIVD KVVNPTNKQV IMENQPKEIG NPIKKETADK VRDLMERVIT 480
  481 SSKGTGTMYK VDGYPIGGKT GTAQIPNPEN GRYMEGKENY IFSFLGMAPI DDPELIVYLA 540
  541 IKQPKLKGDE YGAQPLAEIF KPVVKNSLEY LKVRPYTEKQ MADATEKSQL KVQNYVNQSM 600
  601 GTVENNVKKE KLQPITLGEG KIIKQYPQSG EVMSEGDRIF LLGKNATMPN LQGWSMRDVM 660
  661 YFSKLLKLDL KTSGTGYVTS QSIKKGQAIQ EGDVLELELE PPLQPLTEAN TN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	125.0
Match:	1rp5A
Description:	PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
drug binding	3.43867028493374	bayes_pls_golite062009
serine-type D-Ala-D-Ala carboxypeptidase activity	3.12650314537616	bayes_pls_golite062009
penicillin binding	2.89507018520983	bayes_pls_golite062009
serine-type carboxypeptidase activity	2.70174066798582	bayes_pls_golite062009
serine-type exopeptidase activity	2.69091897402517	bayes_pls_golite062009
carboxypeptidase activity	1.96547160092829	bayes_pls_golite062009
hydrolase activity	1.90776959475284	bayes_pls_golite062009
catalytic activity	1.85492008367309	bayes_pls_golite062009
peptidase activity	1.51270018803999	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.27480861613963	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.13698125224034	bayes_pls_golite062009
binding	1.11566650386305	bayes_pls_golite062009
serine hydrolase activity	0.402878339821269	bayes_pls_golite062009
serine-type peptidase activity	0.392678049813626	bayes_pls_golite062009
exopeptidase activity	0.150639262435765	bayes_pls_golite062009
protein binding	0.0666688846338231	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: