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View Structure Prediction Details

Protein: gi|30257254, gi|...
Organism: Bacillus anthracis str. Ames
Length: 708 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257254, gi|....

Description E-value Query
Range
Subject
Range
gi|228652624, gi... - gi|229130819|ref|ZP_04259768.1| Penicillin-binding protein transpeptidase [Bacillus cereus BDRD-Cer4...
gi|30020747, gi|... - gi|30020747|ref|NP_832378.1| penicillin-binding protein transpeptidase [Bacillus cereus ATCC 14579],...
0.0 [1..707] [1..707]
gi|42737645, gi|... - gi|42781722|ref|NP_978969.1| penicillin-binding protein [Bacillus cereus ATCC 10987], gi|42737645|gb...
0.0 [1..707] [1..707]
gi|49333229, gi|... - gi|49481673|ref|YP_036746.1| penicillin-binding protein transpeptidase domain-containing protein [Ba...
0.0 [1..708] [1..708]
gi|52142859, gi|... - gi|52142859|ref|YP_083970.1| penicillin-binding protein transpeptidase domain-containing protein [Ba...
0.0 [1..708] [1..708]
gi|65319943, gi|... - gi|65319943|ref|ZP_00392902.1| COG0768: Cell division protein FtsI/penicillin-binding protein 2 [Bac...
0.0 [1..708] [1..708]
gi|47558368, gi|... - gi|47564216|ref|ZP_00235261.1| penicillin-binding protein 3 [Bacillus cereus G9241], gi|47558368|gb|...
0.0 [11..708] [17..716]

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Predicted Domain #1
Region A:
Residues: [1-708]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKQEKKSGR AVTMRLNILF FCVFILFSAM IIQLGKVQII DGETYKNEVE KRENATVSLS  60
   61 VPRGKIFDRE GNPVVDNKSL RTITYTKMKG VKSEEILKTA RQLADIIEIP QEDIDKLTET 120
  121 DKKDFWMQLN PTLTEKLVSK KEINKFRDKD ITGKNLDKKI EELKRKRVTD KNLQDLTDKD 180
  181 IKVLAIKSKM TSGYQMAPQI IKKDVSEKEF TIISEGLANL PGVDVSVDWE RVYVNDGLFR 240
  241 SVLGNVSNSD EGLPSERLDY YLVRDYSRND RVGKSYIEQQ YEDVLHGTKK EVRSVADKQG 300
  301 TTIRTETISE GKSGKNLTLT IDMELQKKVE ESIEKILKAY KGSESMLDRA FVVMMNPKNG 360
  361 QVLSMAGKRL VEKDGKTEIE DYALGTMTSS YELGSTVKGA TVLTGFETKA ITPGTYFYDA 420
  421 PMKFKGTREK KSWKEFGNID DLRALQVSSN VYMFHTALKI AGVDYVRNSS LNIKQEYFDK 480
  481 MRYYFRQFGL GVPTGIDLPN ETAGQIGKKD NQPGFLLDYS IGQYDTYTPL QLVQYISTIA 540
  541 NGGYRMKPQI VQEVREQTSQ KDEIGKVVHA VEPIVLNKVD MKEEYIKQVK EGFRKVFQDG 600
  601 DGTGVRAFQK ASYKPAGKTG TAQTVYGGES DIGRNEKGER RECYNLTLAG YAPYDNPEVA 660
  661 FSVVVPWVMN DKSGINSDIG KEVLDAYFEL KNKRLTGETL QKDSSQEG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.09691
Match: 1qmeA
Description: Penicillin-binding protein 2x (pbp-2x), c-terminal domain; Penicillin-binding protein 2x (pbp-2x), N-terminal domain; Penicillin-binding protein 2x (pbp-2x), transpeptidase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
serine-type D-Ala-D-Ala carboxypeptidase activity 3.12650314537616 bayes_pls_golite062009
penicillin binding 2.89507018520983 bayes_pls_golite062009
drug binding 2.8584507881707 bayes_pls_golite062009
serine-type carboxypeptidase activity 2.70174066798582 bayes_pls_golite062009
serine-type exopeptidase activity 2.69091897402517 bayes_pls_golite062009
carboxypeptidase activity 1.96547160092829 bayes_pls_golite062009
hydrolase activity 1.90776959475284 bayes_pls_golite062009
catalytic activity 1.85492008367309 bayes_pls_golite062009
peptidase activity 1.51270018803999 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.27480861613963 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1.13698125224034 bayes_pls_golite062009
binding 1.11566650386305 bayes_pls_golite062009
serine hydrolase activity 0.402878339821269 bayes_pls_golite062009
serine-type peptidase activity 0.392678049813626 bayes_pls_golite062009
exopeptidase activity 0.150639262435765 bayes_pls_golite062009
protein binding 0.0666688846338231 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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