YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49184318, gi\|...
Organism:	Bacillus anthracis str. Sterne
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49184318, gi|....

Description	E-value	Query Range	Subject Range
gi\|52143954, gi\|... - gi\|52143954\|ref\|YP_082874.1\| potassium/sodium uptake protein [Bacillus cereus E33L], gi\|51977423\|gb\|... gi\|49477209, gi\|... - gi\|49477209\|ref\|YP_035608.1\| potassium/sodium uptake protein [Bacillus thuringiensis serovar konkuki... gi\|196047300, gi... - gi\|196047300\|ref\|ZP_03114514.1\| potassium uptake protein, TrkH family [Bacillus cereus 03BB108], gi\|... gi\|196040759, gi... - gi\|196040759\|ref\|ZP_03108058.1\| potassium uptake protein, TrkH family [Bacillus cereus NVH0597-99], ...	0.0	[1..447]	[1..447]
gi\|47566279, gi\|... - gi\|47566279\|ref\|ZP_00237307.1\| potassium uptake protein KtrB [Bacillus cereus G9241], gi\|47556832\|gb...	0.0	[1..447]	[1..447]
gi\|42736503, gi\|... - gi\|42780583\|ref\|NP_977830.1\| TrkH family potassium uptake protein [Bacillus cereus ATCC 10987], gi\|4...	0.0	[1..447]	[1..447]
gi\|218233954, gi... - gi\|218233954\|ref\|YP_002366171.1\| potassium uptake protein, TrkH family [Bacillus cereus B4264], gi\|2... gi\|228633721, gi... - gi\|229149690\|ref\|ZP_04277920.1\| Potassium/sodium uptake protein [Bacillus cereus m1550], gi\|22863372... gi\|206967613, gi... - gi\|206967613\|ref\|ZP_03228569.1\| potassium uptake protein, TrkH family [Bacillus cereus AH1134], gi\|2... gi\|228656744, gi... - gi\|229126804\|ref\|ZP_04255816.1\| Potassium/sodium uptake protein [Bacillus cereus BDRD-Cer4], gi\|2286... gi\|228674416, gi... - gi\|229108947\|ref\|ZP_04238548.1\| Potassium/sodium uptake protein [Bacillus cereus Rock1-15], gi\|22867... gi\|228704547, gi... - gi\|229078674\|ref\|ZP_04211228.1\| Potassium/sodium uptake protein [Bacillus cereus Rock4-2], gi\|228704... gi\|30019540, gi\|... - gi\|30019540\|ref\|NP_831171.1\| potassium uptake protein KtrB [Bacillus cereus ATCC 14579], gi\|29895084... gi\|228713987, gi... - gi\|229069042\|ref\|ZP_04202334.1\| Potassium/sodium uptake protein [Bacillus cereus F65185], gi\|2287139...	0.0	[1..447]	[1..447]
gi\|152974919, gi... - gi\|89202100\|ref\|ZP_01180830.1\| K+ transporter Trk [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|...	0.0	[1..447]	[1..447]
gi\|91192126, gi\|... - gi\|91223313\|ref\|ZP_01258579.1\| putative Na+-transporting ATP synthase [Vibrio alginolyticus 12G01], ...	1.0E-98	[1..447]	[9..454]
gi\|82721725, gi\|... - gi\|82740958\|ref\|ZP_00903690.1\| K+ transporter Trk [Shewanella sp. W3-18-1], gi\|82721725\|gb\|EAP56559....	2.0E-98	[18..447]	[55..484]
gi\|116185726, gi... - gi\|75856600\|ref\|ZP_00764225.1\| COG0168: Trk-type K+ transport systems, membrane components [Vibrio s...	2.0E-98	[1..447]	[9..454]
gi\|28901285, gi\|... - gi\|28901285\|ref\|NP_800940.1\| putative Na+-transporting ATP synthase [Vibrio parahaemolyticus RIMD 22... gi\|28809798 - gi\|28809798\|dbj\|BAC62773.1\| putative Na+-transporting ATP synthase [Vibrio parahaemolyticus RIMD 221...	3.0E-98	[1..447]	[9..454]
gi\|52787678, gi\|... - gi\|52787678\|ref\|YP_093507.1\| YubG [Bacillus licheniformis ATCC 14580], gi\|52350180\|gb\|AAU42814.1\| Yu...	5.0E-98	[10..447]	[11..448]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVTKRQRLY NRFIRLNPPQ ILALGFFCLI VVGGLLLKLP FATKVHISWV DAFFTATSAA  60
   61 TVTGLGVVDT ASTFTMFGEI VIMFLIQTGG LGLMTIAILI VWVLGKKIGL RHRLLIGEAF 120
  121 NQTNIGGLVK LVKRVFIFSI CIEFIGVIFL SFRFIPEFGF GKGIHYSIFH VIASYNNAGF 180
  181 ALWPDNLTRY VGDPIINIGI CSLIVIGGLG FTVLIDIWYS RSFRKL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [227-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLHSKIMIVG TVALNVIAMI VIFILEYNNV KTLGNLPLNE KLWASFFQGI TPRTAGFNTV  60
   61 DYGGMEESSI LFTMVLMFIG AGSVSTGGGI KLTTFVILVT SVLSFFRKKE EIVLFQRTIK 120
  121 MSTVTRALAI AVASQILIFA AVFVLMLTEN FSFIQLLFET ISAFGTVGLT MGITAKLSAF 180
  181 GKCIIMFVMF CGLIGPLTLV FSLARPAKQK IKYPSEDVFT G

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.0
Match:	2a0lA
Description:	Crystal structure of KvAP-33H1 Fv complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	6.97421456325005	bayes_pls_golite062009
voltage-gated potassium channel activity	6.93926669126255	bayes_pls_golite062009
voltage-gated cation channel activity	6.85197806762042	bayes_pls_golite062009
voltage-gated ion channel activity	6.68953517879833	bayes_pls_golite062009
voltage-gated channel activity	6.66667969342152	bayes_pls_golite062009
metal ion transmembrane transporter activity	5.60647618241473	bayes_pls_golite062009
cation channel activity	5.09551684793166	bayes_pls_golite062009
cation transmembrane transporter activity	4.88789838906314	bayes_pls_golite062009
ion transmembrane transporter activity	4.80939024913503	bayes_pls_golite062009
inward rectifier potassium channel activity	4.64079808042939	bayes_pls_golite062009
ion channel activity	4.50553553033114	bayes_pls_golite062009
gated channel activity	4.47618233399604	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.43208330555032	bayes_pls_golite062009
substrate-specific channel activity	4.39833449623615	bayes_pls_golite062009
passive transmembrane transporter activity	4.38139555510307	bayes_pls_golite062009
channel activity	4.38139555510307	bayes_pls_golite062009
transporter activity	2.77619896060397	bayes_pls_golite062009
transmembrane transporter activity	2.65613366364107	bayes_pls_golite062009
ligand-gated ion channel activity	2.63030973607925	bayes_pls_golite062009
ligand-gated channel activity	2.63030973607925	bayes_pls_golite062009
substrate-specific transporter activity	2.60593795082679	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: