YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49178177, gi\|...
Organism:	Bacillus anthracis str. Sterne
Length:	449 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49178177, gi|....

Description	E-value	Query Range	Subject Range
gi\|228704673, gi... - gi\|229078603\|ref\|ZP_04211160.1\| H(+)-transporting two-sector ATPase [Bacillus cereus Rock4-2], gi\|22... gi\|229068969, gi... - gi\|229068969\|ref\|ZP_04202262.1\| H(+)-transporting two-sector ATPase [Bacillus cereus F65185], gi\|228... gi\|228951799, gi... - gi\|228951799\|ref\|ZP_04113897.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis serovar ... gi\|229177825, gi... - gi\|229177825\|ref\|ZP_04305198.1\| H(+)-transporting two-sector ATPase [Bacillus cereus 172560W], gi\|22... gi\|228656673, gi... - gi\|229126733\|ref\|ZP_04255745.1\| H(+)-transporting two-sector ATPase [Bacillus cereus BDRD-Cer4], gi\|... gi\|29895015, gi\|... - gi\|30019471\|ref\|NP_831102.1\| potassium uptake protein KtrB [Bacillus cereus ATCC 14579], gi\|29895015...	5.0E-98	[1..449]	[1..449]
gi\|89157516, gi\|... - gi\|89204455\|ref\|ZP_01183032.1\| Cation transporter [Bacillus weihenstephanensis KBAB4], gi\|89157516\|g...	1.0E-97	[1..449]	[1..449]
gi\|218896350, gi... - gi\|218896350\|ref\|YP_002444761.1\| sodium transporter family protein [Bacillus cereus G9842], gi\|21854... gi\|74490137, gi\|... - gi\|75762377\|ref\|ZP_00742251.1\| Potassium uptake protein ktrB [Bacillus thuringiensis serovar israele... gi\|228795317, gi... - gi\|228964377\|ref\|ZP_04125492.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis serovar ... gi\|228899999, gi... - gi\|228899999\|ref\|ZP_04064235.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis IBL 4222...	2.0E-96	[1..449]	[1..449]
gi\|89200907, gi\|... - gi\|89200907\|ref\|ZP_01179656.1\| Cation transporter [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|...	6.0E-96	[1..449]	[1..449]
gi\|42780506, gi\|... - gi\|42780506\|ref\|NP_977753.1\| sodium transporter family protein [Bacillus cereus ATCC 10987], gi\|4273...	2.0E-94	[1..449]	[1..449]
gi\|49236347, gi\|... - gi\|83590590\|ref\|YP_430599.1\| K+ transporter Trk [Moorella thermoacetica ATCC 39073], gi\|83573504\|gb\|...	3.0E-94	[4..449]	[1..443]
gi\|229154985, gi... - gi\|229154985\|ref\|ZP_04283099.1\| H(+)-transporting two-sector ATPase [Bacillus cereus ATCC 4342], gi\|... gi\|47566207, gi\|... - gi\|47566207\|ref\|ZP_00237235.1\| MW0904 [Bacillus cereus G9241], gi\|47556760\|gb\|EAL15091.1\| MW0904 [Ba...	3.0E-94	[1..449]	[1..449]
gi\|228926448, gi... - gi\|228926448\|ref\|ZP_04089520.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis serovar ... gi\|228913989, gi... - gi\|228913989\|ref\|ZP_04077611.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis serovar ... gi\|254682523 - gi\|254682523\|ref\|ZP_05146384.1\| sodium transporter family protein [Bacillus anthracis str. CNEVA-906... gi\|229183611, gi... - gi\|229183611\|ref\|ZP_04310834.1\| H(+)-transporting two-sector ATPase [Bacillus cereus BGSC 6E1], gi\|2... gi\|229120957, gi... - gi\|229120957\|ref\|ZP_04250199.1\| H(+)-transporting two-sector ATPase [Bacillus cereus 95/8201], gi\|22... gi\|49480070, gi\|... - gi\|49480070\|ref\|YP_035545.1\| cation transporter [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|228932699, gi... - gi\|228932699\|ref\|ZP_04095572.1\| H(+)-transporting two-sector ATPase [Bacillus thuringiensis serovar ... gi\|254740371 - gi\|254740371\|ref\|ZP_05198062.1\| sodium transporter family protein [Bacillus anthracis str. Kruger B] gi\|254726184 - gi\|254726184\|ref\|ZP_05187966.1\| sodium transporter family protein [Bacillus anthracis str. A1055] gi\|218902525, gi... - gi\|218902525\|ref\|YP_002450359.1\| sodium transporter family protein [Bacillus cereus AH820], gi\|21853... gi\|170669239, gi... - gi\|170686716\|ref\|ZP_02877936.1\| sodium transporter family protein [Bacillus anthracis str. A0465], g... gi\|167634393, gi... - gi\|167634393\|ref\|ZP_02392714.1\| sodium transporter family protein [Bacillus anthracis str. A0442], g...	4.0E-94	[1..449]	[1..449]
gi\|51977486, gi\|... - gi\|52144017\|ref\|YP_082811.1\| cation transporter [Bacillus cereus E33L], gi\|51977486\|gb\|AAU19036.1\| c...	4.0E-94	[1..449]	[1..449]
gi\|89099299, gi\|... - gi\|89099299\|ref\|ZP_01172176.1\| hypothetical protein B14911_22012 [Bacillus sp. NRRL B-14911], gi\|890...	6.0E-94	[4..449]	[5..451]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDIKKFLQK LRPVQLIVLF YLLAVVVSVI LLSLPFVTKS GVKWTFIDAL FTSVSVVSVT  60
   61 GLSVVTISDT FTTAGIIILA LILQLGGLGI MALGTFVWII TGKKIGLQRR RLIMADHNQG 120
  121 NLSGLVELMR SILIVIISIE LIGAILLGTR FLLYFPTWQE AYFHGFFAAV SATTNGGFDL 180
  181 TGQSLIPYKK DYIVQMIHML LIILGAIGFP VLMEVKQFLS KRGQQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [226-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFRFSLFTKL TTTTFFALVV VGTIMIFLLE RNHFLVGKSW HETVFYTLFQ SVTTRSGGLA  60
   61 TMDILELSQP TLLFMSILMF IGASPSSVGG GIRTTTFAVS ILSLYTFARG GRTVRVFKRQ 120
  121 IHEEDVLKAS VVMTMGILLC ATALFILSIT ENVPLMSLIV EVCSAFGTTG LSTGITPDLT 180
  181 TVGKLVLIVL MFIGRVGILT FILASGGREQ PPRYKYPKER IIIG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.969
Match:	1xl4A
Description:	Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	3.99407337282834	bayes_pls_golite062009
voltage-gated potassium channel activity	3.91073248991201	bayes_pls_golite062009
voltage-gated cation channel activity	3.77922383565762	bayes_pls_golite062009
voltage-gated ion channel activity	3.67556652361095	bayes_pls_golite062009
voltage-gated channel activity	3.66476584559855	bayes_pls_golite062009
metal ion transmembrane transporter activity	3.06020723789016	bayes_pls_golite062009
cation transmembrane transporter activity	2.8177667975893	bayes_pls_golite062009
ion transmembrane transporter activity	2.77861584057135	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.55687545340392	bayes_pls_golite062009
cation channel activity	2.00851920503891	bayes_pls_golite062009
inward rectifier potassium channel activity	1.84105357682135	bayes_pls_golite062009
ion channel activity	1.48267500978135	bayes_pls_golite062009
substrate-specific channel activity	1.38959552955997	bayes_pls_golite062009
passive transmembrane transporter activity	1.38552473022796	bayes_pls_golite062009
channel activity	1.38552473022796	bayes_pls_golite062009
gated channel activity	1.38417227760594	bayes_pls_golite062009
transporter activity	1.2272927234572	bayes_pls_golite062009
transmembrane transporter activity	1.08210454998006	bayes_pls_golite062009
binding	0.800792616749565	bayes_pls_golite062009
substrate-specific transporter activity	0.778889998230651	bayes_pls_golite062009
G-protein activated inward rectifier potassium channel activity	0.716251734128359	bayes_pls_golite062009
protein binding	0.363226530477833	bayes_pls_golite062009
ATP-activated inward rectifier potassium channel activity	0.212285519079815	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: