YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24349580, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	365 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24349580, gi|....

Description	E-value	Query Range	Subject Range
gi\|113888199, gi... - gi\|114046757\|ref\|YP_737307.1\| A/G-specific DNA-adenine glycosylase [Shewanella sp. MR-7], gi\|1138881...	347.0	[0..1]	[365..1]
gi\|78504971, gi\|... - gi\|78687322\|ref\|ZP_00852074.1\| A/G-specific adenine glycosylase MutY [Shewanella sp. ANA-3], gi\|7850...	346.0	[0..1]	[365..1]
gi\|82404408, gi\|... - gi\|82497582\|ref\|ZP_00883114.1\| A/G-specific adenine glycosylase MutY [Shewanella sp. MR-4], gi\|82404...	343.0	[0..1]	[365..1]
gi\|112702912 - gi\|112702912\|emb\|CAL34131.1\| A/G-specific adenine glycosylase [Enterobacter sakazakii]	342.0	[0..1]	[355..1]
gi\|91073918, gi\|... - gi\|91212344\|ref\|YP_542330.1\| adenine DNA glycosylase [Escherichia coli UTI89], gi\|91073918\|gb\|ABE087... gi\|226899425, gi... - gi\|237706385\|ref\|ZP_04536866.1\| adenine DNA glycosylase [Escherichia sp. 3_2_53FAA], gi\|226899425\|gb...	341.0	[0..2]	[353..11]
gi\|22127215, gi\|... - gi\|22127215\|ref\|NP_670638.1\| adenine DNA glycosylase [Yersinia pestis KIM], gi\|21960283\|gb\|AAM86889.... gi\|45443228, gi\|... - gi\|45443228\|ref\|NP_994767.1\| adenine DNA glycosylase [Yersinia pestis biovar Microtus str. 91001], g...	341.0	[0..1]	[354..44]
gi\|115514312, gi... - gi\|117625188\|ref\|YP_854176.1\| adenine DNA glycosylase [Escherichia coli APEC O1], gi\|115514312\|gb\|AB... gi\|218366721, gi... - gi\|218559952\|ref\|YP_002392865.1\| adenine DNA glycosylase [Escherichia coli S88], gi\|218366721\|emb\|CA...	340.0	[0..2]	[353..1]
gi\|167421991, gi... - gi\|167421991\|ref\|ZP_02313744.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Orientalis ... gi\|167050802, gi... - gi\|167400094\|ref\|ZP_02305612.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Antiqua str... gi\|166206169, gi... - gi\|166212877\|ref\|ZP_02238912.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Antiqua str... gi\|165990761, gi... - gi\|166010275\|ref\|ZP_02231173.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Antiqua str... gi\|167426696, gi... - gi\|167426696\|ref\|ZP_02318449.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Mediaevalis... gi\|108813310, gi... - gi\|108813310\|ref\|YP_649077.1\| adenine DNA glycosylase [Yersinia pestis Nepal516], gi\|108776958\|gb\|AB... gi\|145597869, gi... - gi\|145597869\|ref\|YP_001161945.1\| adenine DNA glycosylase [Yersinia pestis Pestoides F], gi\|145209565... gi\|108806309, gi... - gi\|108806309\|ref\|YP_650225.1\| adenine DNA glycosylase [Yersinia pestis Antiqua], gi\|108778222\|gb\|ABG... gi\|165914809, gi... - gi\|89102125\|ref\|ZP_01174785.1\| COG1194: A/G-specific DNA glycosylase [Yersinia pestis biovar Orienta... gi\|165925102, gi... - gi\|165925102\|ref\|ZP_02220934.1\| A/G-specific adenine glycosylase [Yersinia pestis biovar Orientalis ...	338.0	[0..1]	[354..1]
gi\|77959941 - gi\|77959941\|ref\|ZP_00823854.1\| COG1194: A/G-specific DNA glycosylase [Yersinia mollaretii ATCC 43969...	338.0	[0..1]	[354..20]
gi\|75241243, gi\|... - gi\|75241243\|ref\|ZP_00725105.1\| COG1194: A/G-specific DNA glycosylase [Escherichia coli F11], gi\|1911... gi\|218691085, gi... - gi\|218691085\|ref\|YP_002399297.1\| adenine DNA glycosylase [Escherichia coli ED1a], gi\|218428649\|emb\|C... gi\|110643110, gi... - gi\|110643110\|ref\|YP_670840.1\| adenine DNA glycosylase [Escherichia coli 536], gi\|110344702\|gb\|ABG709...	338.0	[0..2]	[353..1]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSTASFATR IVNWYDNHGR KTLPWQQDKT PYRVWVSEIM LQQTQVATVI PYYQRFMQRF  60
   61 PNVLALANAP DDEVLHHWTG LGYYARARNL HKAAKMIRDE YQGQFPTDFE QVLALPGIGR 120
  121 STAGAVLSLS LGQHHPILDG NVKRVLARHG AIEGWPGQKP VEERLWQLTE QLTPQQDIQK 180
  181 YNQAMMDIGA SICTRSKPNC AACPVAVDCK AQLMGRQTDF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.69897
Match:	1kg2A
Description:	Catalytic domain of MutY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.8124964619976	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	4.26870112679392	bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity	3.71152530486175	bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity	2.49872706126491	bayes_pls_golite062009
hydrolase activity	2.39042189031819	bayes_pls_golite062009
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	2.21048599823382	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.18053745735048	bayes_pls_golite062009
catalytic activity	2.13345932727422	bayes_pls_golite062009
damaged DNA binding	2.00388798014411	bayes_pls_golite062009
nucleic acid binding	1.77735453133546	bayes_pls_golite062009
DNA binding	1.70910448624199	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.5832578018127	bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity	1.32985950765371	bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity	1.2016453685638	bayes_pls_golite062009
binding	1.15752946565805	bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity	1.06383943982125	bayes_pls_golite062009
transcription regulator activity	0.953912155797942	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.879508131574476	bayes_pls_golite062009
structure-specific DNA binding	0.85419760398899	bayes_pls_golite062009
purine-specific mismatch base pair DNA N-glycosylase activity	0.68578837518217	bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity	0.661651574677137	bayes_pls_golite062009
double-stranded DNA binding	0.57099109384393	bayes_pls_golite062009
transcription factor activity	0.181268475863531	bayes_pls_golite062009
protein binding	0.0921713980805489	bayes_pls_golite062009
carbon-oxygen lyase activity	0.0676784802238829	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [221-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGKKPKKTIP EKSAWMLVLF KDNQVFLAKR PPAGIWGGLW CFPEFSSEAA LNTELEAQGY  60
   61 QPTQLEPLIG FRHTFSHFHL DIQPMLLDLD KWASGKPSVG AIMEQNQSLW YNINQPSKVG 120
  121 LAAATERVLA NLGSLVAIAR NHCSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.0
Match:	1mutA
Description:	NMR STUDY OF MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
MutLbeta complex binding	3.54991362477413	bayes_pls_golite062009
MutSbeta complex binding	3.54991362477413	bayes_pls_golite062009
hydrolase activity	1.97832429767892	bayes_pls_golite062009
catalytic activity	1.49075808737475	bayes_pls_golite062009
nucleic acid binding	1.06392208444166	bayes_pls_golite062009
binding	0.804982034963737	bayes_pls_golite062009
pyrophosphatase activity	0.546676461152337	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.00783582682768413	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: