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View Structure Prediction Details

Protein: gi|24349275, gi|...
Organism: Shewanella oneidensis MR-1
Length: 542 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24349275, gi|....

Description E-value Query
Range
Subject
Range
gi|78687840, gi|... - gi|78687840|ref|ZP_00852575.1| Helix-turn-helix, AraC type:HhH-GPD [Shewanella sp. ANA-3], gi|785043...
307.0 [0..11] [542..11]
gi|82497826, gi|... - gi|82497826|ref|ZP_00883351.1| Helix-turn-helix, AraC type:HhH-GPD [Shewanella sp. MR-4], gi|8240414...
307.0 [0..1] [542..1]
gi|113888380, gi... - gi|78691979|ref|ZP_00856561.1| Helix-turn-helix, AraC type:HhH-GPD [Shewanella sp. MR-7], gi|7850862...
304.0 [0..1] [542..1]
gi|113907762, gi... - gi|160876050|ref|YP_001555366.1| AraC family transcriptional regulator [Shewanella baltica OS195], g...
287.0 [0..28] [541..29]
gi|68543396, gi|... - gi|68543396|ref|ZP_00583103.1| Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-termin...
282.0 [0..28] [541..29]
gi|120598329, gi... - gi|82742461|ref|ZP_00905153.1| Helix-turn-helix, AraC type:HhH-GPD [Shewanella sp. W3-18-1], gi|8272...
280.0 [0..28] [541..29]
gi|146293593, gi... - gi|77816265|ref|ZP_00815464.1| Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-termin...
279.0 [0..28] [541..29]
gi|28808183, gi|... - gi|28899900|ref|NP_799555.1| ada regulatory protein [Vibrio parahaemolyticus RIMD 2210633], gi|28808...
gi|28808183 - gi|28808183|dbj|BAC61388.1| ada regulatory protein [Vibrio parahaemolyticus RIMD 2210633]
263.0 [0..25] [542..6]
gi|90329297, gi|... - gi|90409944|ref|ZP_01217961.1| hypothetical ada regulatory protein [Photobacterium profundum 3TCK], ...
263.0 [0..26] [540..15]
gi|114335170, gi... - gi|69953722|ref|ZP_00640746.1| Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding [Shewanella fr...
262.0 [0..25] [539..7]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQISVSLNS AAKPPHEQVS AALEDCHLSA SVCREARTSR DPRFDGKFFV GVLTTGIYCR  60
   61 TVCPAVAPKE ENVRYFDSAI KAAQAGLRPC LRCRPDSAPG SNPWKGTGTT LDRAIGLIEA 120
  121 GALSGEHGLT VEALADKLGI SSRYLNKLFT SGFGTSPKQY ALYRQLLFAK QLLHQTQLPI 180
  181 TQIALAAGFN SIRRFNEAFQ QALQLTPTQL RKSSQKSAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1wpkA
Description: Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [220-542]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIDEGEGSDT ACPQAMPAHS LSLYQYYRPP LDWQAQLAFY RLRAVAGMEW FSNTDNDCLE  60
   61 KIAQDKQALE YGRTLQIDDI RAVVHIIHEA HLHRFKLTLT FTPDSPIAGL QKLITQVRRI 120
  121 LDLDADMQQI EHNLQRLTDL KLIPKSGLRI PGAGSLFEAG CRAILGQQVT VVQATKLLNL 180
  181 LVDAYGERFS LNGREYRLFP IPQAIRGASL DELKMPGARK LALNALAAFI CERPNASVDD 240
  241 WLEVKGIGPW TIAYAKLRGL GEPNIFLHTD LIVKKQLLVS VAEQNGLDAQ ALKQLDYLTL 300
  301 CQRISADIAP WGSYLTFQLW SNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.221849
Match: 1dizA
Description: 3-Methyladenine DNA glycosylase II (gene alkA or aidA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 4.08559331236111 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 3.73234184319832 bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity 3.12421941323765 bayes_pls_golite062009
transcription regulator activity 3.10433798291017 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.54759386266723 bayes_pls_golite062009
catalytic activity 2.50389926428623 bayes_pls_golite062009
DNA binding 2.2702471315134 bayes_pls_golite062009
nucleic acid binding 2.21292342418702 bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity 1.80199518353554 bayes_pls_golite062009
alkylbase DNA N-glycosylase activity 1.75218522602775 bayes_pls_golite062009
binding 1.38924406467484 bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity 1.14337995879633 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.10322636524937 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.04609043340607 bayes_pls_golite062009
transcription factor activity 0.85246847842951 bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity 0.473206156100251 bayes_pls_golite062009
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity 0.433793047073349 bayes_pls_golite062009
uracil DNA N-glycosylase activity 0.29478804124408 bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity 0.253198605718519 bayes_pls_golite062009
protein binding 0.19712675878092 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle