YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24373055, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	589 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24373055, gi|....

Description	E-value	Query Range	Subject Range
gi\|115511461, gi... - gi\|117622337\|ref\|YP_851250.1\| glutathione-regulated potassium-efflux system protein KefC [Escherichi...	312.0	[0..3]	[589..26]
KEFC_SHISS - Glutathione-regulated potassium-efflux system protein KefC OS=Shigella sonnei (strain Ss046) GN=kefC...	308.0	[0..3]	[589..2]
gi\|253976282, gi... - gi\|254286975\|ref\|YP_003052723.1\| glutathione-regulated potassium-efflux system protein [Escherichia ... gi\|251783613, gi... - gi\|251783613\|ref\|YP_002997917.1\| hypothetical protein B21_00050 [Escherichia coli BL21], gi\|24237588... gi\|253972073, gi... - gi\|254160172\|ref\|YP_003043280.1\| glutathione-regulated potassium-efflux system protein [Escherichia ... gi\|226840570, gi... - gi\|254037464\|ref\|ZP_04871541.1\| potassium:proton antiporter [Escherichia sp. 1_1_43], gi\|226840570\|g... KEFC_ECO8A - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli O8 (strain IAI1) GN=k... KEFC_ECOSE - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli (strain SE11) GN=kefC... KEFC_ECOHS - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli O9:H4 (strain HS) GN=... KEFC_SHIBS - Glutathione-regulated potassium-efflux system protein KefC OS=Shigella boydii serotype 4 (strain Sb2... gi\|83584908, gi\|... - gi\|83584908\|ref\|ZP_00923565.1\| COG0475: Kef-type K+ transport systems, membrane components [Escheric... KEFC_SHIB3 - Glutathione-regulated potassium-efflux system protein KefC OS=Shigella boydii serotype 18 (strain CD...	308.0	[0..3]	[589..2]
KEFC_ECO55 - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli (strain 55989 / EAEC)... KEFC_ECO24 - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli O139:H28 (strain E243...	307.0	[0..3]	[589..2]
EG10521 - potassium:proton antiporter / NEM-activatable K+ /H+ antiporter KEFC_ECOLC - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli (strain ATCC 8739 / D... KEFC_ECODH - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli (strain K12 / DH10B) ... KEFC_ECOLI - Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter) - Escherichia coli EG10521 - potassium:proton antiporter / NEM-activatable K+ /H+ antiporter gi\|89106931, gi\|... - gi\|89106931\|ref\|AP_000711.1\| potassium:proton antiporter [Escherichia coli str. K-12 substr. W3110],... gi\|124531319, gi... - gi\|124531319\|ref\|ZP_01701647.1\| potassium efflux system protein [Escherichia coli B], gi\|124498619\|g... KEFC_ECOBW - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli (strain K12 / MC4100 ...	307.0	[0..3]	[589..2]
KEFC_SHIFL - Glutathione-regulated potassium-efflux system protein KefC OS=Shigella flexneri GN=kefC PE=3 SV=1 gi\|30039856, gi\|... - gi\|30061614\|ref\|NP_835785.1\| glutathione-regulated potassium-efflux system protein KefC [Shigella fl... gi\|24050245, gi\|... - gi\|24111493\|ref\|NP_706003.1\| glutathione-regulated potassium-efflux system protein KefC [Shigella fl... gi\|209746940 - gi\|209746940\|gb\|ACI71777.1\| glutathione-regulated K+ efflux antiporter [Escherichia coli]	307.0	[0..3]	[589..2]
gi\|75255702, gi\|... - gi\|75255702\|ref\|ZP_00727468.1\| COG0475: Kef-type K+ transport systems, membrane components [Escheric...	307.0	[0..3]	[589..2]
gi\|194412085, gi... - gi\|75208903\|ref\|ZP_00709180.1\| COG0475: Kef-type K+ transport systems, membrane components [Escheric...	307.0	[0..3]	[589..2]
gi\|191174104, gi... - gi\|75237160\|ref\|ZP_00721208.1\| COG0475: Kef-type K+ transport systems, membrane components [Escheric... KEFC_ECOL5 - Glutathione-regulated potassium-efflux system protein KefC OS=Escherichia coli O6:K15:H31 (strain 53...	307.0	[0..3]	[589..2]
gi\|75227574, gi\|... - gi\|75227574\|ref\|ZP_00714329.1\| COG0475: Kef-type K+ transport systems, membrane components [Escheric...	307.0	[0..3]	[589..2]

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Predicted Domain #1

Region A:
Residues: [1-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEESSLLTSV LLFLLAAVIF VPLGKRFGAG PILSYLAAGV ILGPGGMALV SDPAAVLHFA  60
   61 ELGVVLMLFV LGLELNPSKL WELRSAIFGL GSGQLLLSWA AIGGLAWGFG LSIEAALVVG 120
  121 AALSLSSTAF AVQLMSEHRL LTTPLGRDAF GVLLMQDLAV IPMLLLTAYL APNSAQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [177-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEHHAVPWYW TCVALIGFVL VGKYLLPRVL KLVASSGVRE VLTAFALLLV MGSAQLMEWL  60
   61 GLSAGMGAFL AGIMLANSSY RHQLETDIEP FKGLLLGLFF MAVGMS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [283-589]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLKLFLTDP LLILAILLGM LLIKTLVLML LGRVRHHTWR PSIALGLILA EGGEFAFVLL  60
   61 SQAQLSSIVD DKIAQILVLA IGLSMAVTPM IFTLFRATKP KVVDTRLPDT INVTESEVVI 120
  121 AGFGRVGQIT GRILASSGIP FVALDKDASH VDVIRQYGGE VYFGDARRLD MLMSAGIARS 180
  181 RLLLLAVDSV EDSIEIAQQV KTHFPHINII ARARDRNHAY RLMSLGVTDV FRETFGSALS 240
  241 ASEKILQGLG LSQVQANERV KIFAEHDKKL VIASAAHQND LAKLIDLSNK GKAELESLMR 300
  301 GDRENVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.09691
Match:	1lnqA
Description:	Potassium channel-related protein MthK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.45561375804942	bayes_pls_golite062009
voltage-gated potassium channel activity	7.44058571110681	bayes_pls_golite062009
voltage-gated cation channel activity	7.3386698127529	bayes_pls_golite062009
voltage-gated ion channel activity	7.16469552587678	bayes_pls_golite062009
voltage-gated channel activity	7.14063840809955	bayes_pls_golite062009
metal ion transmembrane transporter activity	5.93188092092616	bayes_pls_golite062009
cation channel activity	5.49362429102263	bayes_pls_golite062009
cation transmembrane transporter activity	5.13805155650973	bayes_pls_golite062009
inward rectifier potassium channel activity	5.0997110076666	bayes_pls_golite062009
ion transmembrane transporter activity	5.04374327766634	bayes_pls_golite062009
ion channel activity	4.88752793243149	bayes_pls_golite062009
gated channel activity	4.87650815860853	bayes_pls_golite062009
substrate-specific channel activity	4.76774891791883	bayes_pls_golite062009
channel activity	4.7460548761362	bayes_pls_golite062009
passive transmembrane transporter activity	4.7460548761362	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.64120459994573	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	3.48222081117811	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.96809690970616	bayes_pls_golite062009
ligand-gated ion channel activity	2.94075163359893	bayes_pls_golite062009
ligand-gated channel activity	2.94075163359893	bayes_pls_golite062009
transporter activity	2.93091397928047	bayes_pls_golite062009
transmembrane transporter activity	2.82224868778929	bayes_pls_golite062009
substrate-specific transporter activity	2.79688978937497	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.13014428099026	bayes_pls_golite062009
potassium ion transmembrane transporter activity	1.34449386905866	bayes_pls_golite062009
catalytic activity	1.03099072397093	bayes_pls_golite062009
active transmembrane transporter activity	0.239024094835991	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: