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View Structure Prediction Details

Protein: SYK_SHEON
Organism: Shewanella oneidensis MR-1
Length: 500 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYK_SHEON.

Description E-value Query
Range		 Subject
Range
SYK_SHESR - Lysine--tRNA ligase OS=Shewanella sp. (strain MR-7) GN=lysS PE=3 SV=1
SYK_SHESA - Lysine--tRNA ligase OS=Shewanella sp. (strain ANA-3) GN=lysS PE=3 SV=1
SYK_SHESM - Lysine--tRNA ligase OS=Shewanella sp. (strain MR-4) GN=lysS PE=3 SV=1
 549.0 [0..1] [500..1]
SYK_SHESW - Lysine--tRNA ligase OS=Shewanella sp. (strain W3-18-1) GN=lysS PE=3 SV=1
SYK_SHEPC - Lysine--tRNA ligase OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=lysS PE=3 SV=1
gi|124546846, gi... - gi|124546846|ref|ZP_01705867.1| lysyl-tRNA synthetase [Shewanella putrefaciens 200], gi|124509716|gb...
 549.0 [0..1] [500..1]
SYK_SHEB8 - Lysine--tRNA ligase OS=Shewanella baltica (strain OS185) GN=lysS PE=3 SV=1
gi|217974575, gi... - gi|217974575|ref|YP_002359326.1| lysyl-tRNA synthetase [Shewanella baltica OS223], gi|217499710|gb|A...
SYK_SHEB9 - Lysine--tRNA ligase OS=Shewanella baltica (strain OS195) GN=lysS PE=3 SV=1
SYK_SHEB5 - Lysine--tRNA ligase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=lysS PE=3 SV=1
 548.0 [0..1] [500..1]
SYK_VIBVY - Lysine--tRNA ligase OS=Vibrio vulnificus (strain YJ016) GN=lysS PE=3 SV=1
 542.0 [0..5] [500..15]
SYK_VIBVU - Lysine--tRNA ligase OS=Vibrio vulnificus GN=lysS PE=3 SV=1
SYK_VIBVU - Lysine--tRNA ligase OS=Vibrio vulnificus (strain CMCP6) GN=lysS PE=3 SV=1
 542.0 [0..5] [500..15]
SYK_SHEDO - Lysine--tRNA ligase OS=Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) GN=lysS P...
 540.0 [0..1] [500..1]
gi|89051641, gi|... - gi|89072537|ref|ZP_01159109.1| lysyl-tRNA synthetase [Photobacterium sp. SKA34], gi|89051641|gb|EAR5...
 539.0 [0..1] [500..1]
gi|90438236, gi|... - gi|90580578|ref|ZP_01236383.1| lysyl-tRNA synthetase [Vibrio angustum S14], gi|90438236|gb|EAS63422....
 539.0 [0..1] [500..1]
SYK_SHELP - Lysine--tRNA ligase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=lysS PE=3 SV=1
 539.0 [0..1] [498..1]
SYK_VIBCH - Lysine--tRNA ligase OS=Vibrio cholerae GN=lysS PE=3 SV=2
SYK_VIBCH - Lysine--tRNA ligase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=lysS...
 538.0 [0..5] [498..15]

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Predicted Domain #1
Region A:
Residues: [1-500] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEQVQDENK LIAERRAKLD SIRPNCSANA HPNTFRRTHK AAELQEKYGQ NTKEELEALG  60
   61 FRTSIAGRIM AKRGPFLVIQ DVSGRIQAYA EKGVQADLKD RYQGLDIGDI IGVTGQLHLS 120
  121 GKGDLYVNME EYQLLTKALR PLPEKFHGLT DQETRYRQRY VDLIVNEESR QAFVMRSKVV 180
  181 AAIRNFMIKK EFMEVETPMM HVIPGGASAR PFITHHNALD MPMYLRIAPE LYLKRLVVGG 240
  241 FERVFEINRN FRNEGLSPRH NPEFTMMEFY MAYADYQDLM DLTEELLSSI AIELLGSAQM 300
  301 PYGEHTVDFG GPYARLSMLE AIQKYNPDNA TIQAMTYEQV KDLEFMRELA ISLGIKIEKF 360
  361 WTCGQLLEEI FGETAEWQLM QPTFITGYPA DISPLARRND DNHFITDRFE FFIGGREVAN 420
  421 GFSELNDAQD QDSRFKAQVD AKDAGDDEAM FYDADYITAL EHGLPPTAGQ GIGIDRLVML 480
  481 FTNTHTIRDV ILFPAMRPQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.0
Match: 1e1oA
Description: Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine-tRNA ligase activity 5.79033103181143 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.53864660125764 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.53864660125764 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 3.52777284894652 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
nucleic acid binding 2.69275272183315 bayes_pls_golite062009
ligase activity 2.56279938346489 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
structural constituent of ribosome 2.43759174701552 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
binding 2.20683882867211 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
structural molecule activity 2.08258913217268 bayes_pls_golite062009
DNA binding 1.97161900822354 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
translation initiation factor activity 0.96756670903925 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.921774798819338 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
structure-specific DNA binding 0.83085643154213 bayes_pls_golite062009
single-stranded DNA binding 0.56590887755068 bayes_pls_golite062009
transcription regulator activity 0.398606646713208 bayes_pls_golite062009
ribonuclease activity 0.305684604963838 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle