YRC Public Data Repository - Protein Structure Prediction

Protein:	GSHB_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	315 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSHB_SHEON.

Description	E-value	Query Range	Subject Range
gi\|114590613 - gi\|114590613\|ref\|XP_516898.2\| PREDICTED: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) [Pan trogl...	264.0	[0..1]	[311..180]
gi\|109043037 - gi\|109043037\|ref\|XP_001096717.1\| PREDICTED: similar to methylcrotonoyl-Coenzyme A carboxylase 1 (alp...	264.0	[0..1]	[311..121]
gi\|62089054 - gi\|62089054\|dbj\|BAD92974.1\| methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) variant [Homo sapiens]	261.0	[0..1]	[311..65]
gi\|49474255, gi\|... - gi\|49474255\|ref\|YP_032297.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Bartonella quintana ...	261.0	[0..1]	[311..2]
gi\|76670627 - gi\|76670627\|ref\|XP_591194.2\| PREDICTED: similar to methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) ...	261.0	[0..1]	[311..49]
gi\|17987346, gi\|... - gi\|17987346\|ref\|NP_539980.1\| acetyl-CoA carboxylase [Brucella melitensis 16M], gi\|17983030\|gb\|AAL522... gi\|25293959 - pir\|\|AI3384 biotin carboxylase (EC 6.3.4.14) [imported] - Brucella melitensis (strain 16M)	260.0	[0..3]	[311..11]
gi\|254730188 - gi\|254730188\|ref\|ZP_05188766.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella abortus ... gi\|254719009 - gi\|254719009\|ref\|ZP_05180820.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella sp. 83/1... gi\|148371387, gi... - gi\|148560130\|ref\|YP_001258883.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella ovis AT... gi\|82699775 - gi\|82699775\|ref\|YP_414349.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella melitensis ... gi\|62289849, gi\|... - gi\|62289849\|ref\|YP_221642.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella abortus bv.... gi\|82615876 - gi\|82615876\|emb\|CAJ10880.1\| Acetyl-CoA carboxylase, biotin carboxylase:Carbamoyl-phosphate synthase ... gi\|189024091, gi... - gi\|189024091\|ref\|YP_001934859.1\| acetyl-CoA carboxylase [Brucella abortus S19], gi\|189019663\|gb\|ACD7... gi\|161335675, gi... - gi\|161618864\|ref\|YP_001592751.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella canis A... gi\|254697290 - gi\|254697290\|ref\|ZP_05159118.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella abortus ... gi\|254693638 - gi\|254693638\|ref\|ZP_05155466.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella abortus ... gi\|23347723, gi\|... - gi\|23501792\|ref\|NP_697919.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella suis 1330],... gi\|254704213 - gi\|254704213\|ref\|ZP_05166041.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella suis bv.... gi\|254701670 - gi\|254701670\|ref\|ZP_05163498.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Brucella suis bv....	258.0	[0..3]	[311..4]

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Predicted Domain #1

Region A:
Residues: [1-315]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKLGIVMDP ISEINIKKDS SFAMLMAAQE RGYQLFYMEM ADLAIVNGVA MGNMRPLKVM  60
   61 NDANHWFELG EAKDTPLSEL NVVLMRKDPP FDTEYIYATY MLERAEEQGV LIVNKPQSLR 120
  121 DANEKLFTAW FSEFTPETIV TRDANRIRAF HQAKGDIILK PLDGMGGTSI FRVKQDDPNL 180
  181 GVIIETLTQY GNQYAMAQAF IPEITKGDKR ILVVDGEPVP YALARIPKKG ETRGNLAAGG 240
  241 SGVAQPLSDS DWKIARAIGP ELKKRGLIFV GLDVIGDKLT EINVTSPTCI REIQAAFDVD 300
  301 ITGMLFDAIE TRLGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.09691
Match:	1gsaA
Description:	STRUCTURE OF GLUTATHIONE SYNTHETASE COMPLEXED WITH ADP AND GLUTATHIONE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutathione synthase activity	3.18460876432532	bayes_pls_golite062009
catalytic activity	2.5009559386228	bayes_pls_golite062009
glutathione binding	2.38364045371863	bayes_pls_golite062009
ligase activity	2.15409885945916	bayes_pls_golite062009
succinate-CoA ligase activity	1.52785506428706	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	0.935432886482705	bayes_pls_golite062009
acid-amino acid ligase activity	0.599203164789408	bayes_pls_golite062009
CoA-ligase activity	0.51228075142462	bayes_pls_golite062009
acid-thiol ligase activity	0.448084116680826	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.351267830197198	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	0.324506681366243	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.239594107637156	bayes_pls_golite062009
CoA carboxylase activity	0.185924207432397	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: